Term
| what increases degrad of PRE-formed PTH in parathyroid cell |
|
Definition
| leukotrienes via lipoxygenase activity |
|
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Term
| rate lim step of glc on insulin secr |
|
Definition
| phosphorylation of glc by glucokinase |
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Term
Is GH diabetogenic?
GH receptor is? |
|
Definition
YEs
Class 1 cytokine receptor that stims tyrosine kinases (JAKS) |
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Term
PTH effects on phosphate resrbtion
PTH eff on vit D and kidney |
|
Definition
decrease po4 res.
Inc 1 alpha hydroxylase and Vit D form |
|
|
Term
|
Definition
| Cytochrome p450 Side chain cleavage enz (SCC)..chol transported to SCC by STAR |
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Term
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Definition
|
|
Term
|
Definition
|
|
Term
3 B HSD
3 Beta Hydroxysteroid DH |
|
Definition
| Pregnenolone to PROGESTERONE |
|
|
Term
ACTH processed for prehormone peptide __
what mediates effects of ACTH? |
|
Definition
|
|
Term
| cAMP activates what step in chol syn |
|
Definition
| STAR and SCC (rate lim steps) |
|
|
Term
Theca cells prod?
Granulosa cells prod? |
|
Definition
Theca-Testost
Gran- Estradiol (has aromatase) |
|
|
Term
| cortisol effects on glycogen |
|
Definition
| facilitates gly syn and storage for emergencies..glc is available via gluconeo and glycogenolysis |
|
|
Term
| major stimulus for aldosterone secr |
|
Definition
|
|
Term
| Androgens conv to estrogens in periph tisues via? |
|
Definition
|
|
Term
| Addison's disease symptoms |
|
Definition
| fatigue weight loss, hypoglycemic..due to adr dysfunct..==PRIMARY HYPOALDOST |
|
|
Term
| disease due to primary HYPERaldost |
|
Definition
|
|
Term
| aldost normal, excessive gluco-dep stimulation of mineralcortico receptor==== |
|
Definition
|
|
Term
rate limiting enzyme of catech biosyn?
major stim of catech release? |
|
Definition
tyrosine hydroxylase TH
hypoglycemia |
|
|
Term
| hsp90 effects on glucocorti |
|
Definition
|
|
Term
| Estradiol effect on LH & GnRH |
|
Definition
|
|
Term
Estradiol on stromal cells?
what suppreses myom contractility |
|
Definition
Es stromal cell prolif
PROGESTERONE suppresses myom contr |
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