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Limbic system
Neurology, SOM 20104
24
Medical
Professional
02/28/2011

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Term
The limbic system consists of what structures?
Definition
Amygdala
Hypothalamus
Hippocampus
Association Cortices
Term
Where is the amygdala located?
Definition
Medial temporal lobe
Term
what is the function of the amygdala?
Definition
Conditioned emotional responses
(destruction associated with impaired threat assesment)
Term
describe the pathway of information to the amygdala?
Definition
Sensory info from cortex -> basolateral nucleus amygdala-> central nucleus -> hypothalamus -> LC -> NE/E
Term
what are the functions of the hypothalamus?
Definition
Hunger/thirst, sex, rage, pleasure, Temperature, carotid blood chemistry, CSF (3rd), circadian rhythm, endocrine
Term
how does the hypothalamus exert control on emotions and internal homeostasis?
Definition
ANS (directly stimulates Locus coeruleus) and Endocrine system (via HPA Axis)
Term
function of orbitofrontal cortex?
Definition
decision making, mood, restraint, impulsivity
Term
the dorsomedial nucleus of the hypothalamus controls what?
Definition
GI tract
(location of binge eating problems)
Term
function of cingulate?
Definition
motivation, proper emotional response (affection, concern), attachment
Term
The paraventricular nucleus of the hypothalamus controls what?
Definition
Water balance/stress
Term
the hypothalmus connects directly to which lobe of the pituitary?
Definition
Posterior pituitary
Term
The hypothalamic-pituitary-adrenal axis
Definition
hypo -> CRH -> ant pit -> ACTH -> adrenal cortex -> cortisol -> adrenal medulla -> NE/E
Term
Function of the hippocampus?
Definition
store cortex memory into long term memory. Associated with declarative memory (facts) and spatial memory. Damage leads to inability to store short term memory
Term
dentate gyrus function?
Definition
cortex surrounding hippocampus that serves to help store memory
Term
function of the parahippocampal gyrus?
Definition
associated with memory retrieval and recognition of scenes
Term
function of the entorhinal cortex?
Definition
pathway in and out of hippocampal formation, associated with spatial memory. Part of the parahippocampal gyrus
Term
function of association cortex?
Definition
complex analysis
planning
restraint
Term
function of Dorsolateral Prefrontal Cortex?
Definition
working memory, executive function, integrates many areas
Term
function of anterior/inferior temporal cortex?
Definition
verbral memory (L), spatial memory (R)
Term
reticular activation system consists of?
Definition
Locus coeruleus (NE)
Raphe nuclei(5HT)
Ventral Tegmenatal nuclei (DA)
Term
function of periacqueductal gray?
Definition
modifies emotional output, involved in pain, sex, rage and fear
Term
stimulation of DL periacqueductal gray provokes?
Definition
defensive response (freezing immobility, running, jumping, tachycardia, and increases in blood pressure and muscle tone)
Term
stimulation of caudal VL periacqueductal gray provokes?
Definition
immobile, relaxed posturing
Term
function of accumbens?
Definition
associated with dopamine projections and reward system

leads to increased likelihood of conditioned motor reponse and repeating rewarded behaviors
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