Term
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Definition
Endothelium: E-selectin & P-selectin
Leukocyte: Sialyl Lewis x
E-selectin on endothelium, P-selectin on platelets & endothelium |
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Term
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Definition
Endothelium: ICAM-1
Leukocytes: LFA-1 ("integrin", CD11/CD18, MAC-1) |
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Term
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Definition
| Endothelium (inbetween cells): PECAM-1 |
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Term
| Migration through extracellular matrix (for stroma, give chemotactic factors) |
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Definition
Stroma (chemotactic factors): Bacterial products (N-formyl...) & CILK (C5a, IL-8, Leukotriene B4, Kallikrein)
Leukocytes: various; integrins & CD44 bind matrix proteins |
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Term
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Definition
| Rolling (expressed on endothelium) |
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Term
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Definition
| Rolling (expressed on endothelium) |
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Term
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Definition
| tight binding (expressed on endothelium) |
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Term
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Definition
| Diapedesis (expressed on endothelium, inbetween cells) |
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Term
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Definition
Bacterial products &:
C5a
IL-8
Leukotreine B4
Kallikrein |
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Term
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Definition
| Rolling (expressed on leukocyte) |
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Term
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Definition
Tight binding (expressed on leukocyte)
AKA CD11/CD18, beta-2 integrin, MAC-1 |
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Term
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Definition
| Migration through stroma (expressed on leukocyte), binds extracellular matrix |
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