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Lesson 1: The Endocrine System
Vocabulary
71
Nursing
Undergraduate 2
03/04/2015

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Term
Addison's syndrome
Definition
a condition in which the supply of adrenal steroids is inadequate, either due to damage to the adrenals themselves or to failure of ACTH secretion
Term
adenohypophysis
Definition
the anterior lobe of the pituitary gland that secretes six glycoprotein hormones
Term
adenyl cyclase
Definition
converts a small fraction of the cells suuppl of ATP into cAMP
Term
adrenal medulla
Definition
a branch of the sympathetic nervous system that secretes catecholamines, epinephrine, and norepinephrine
Term
adrenalin
Definition
the catecholamine epinephrine
Term
aldesterone
Definition
an adrenal cortical steriod that plays an important role in regulating both Na+ content, and with ADH, extracellular fluid volume
Term
alkalosis
Definition
excesssive plasma alkalinity
Term
angiotensin I
Definition
converts to angiotensin II by angiotensin-converting enzyme ACE
Term
angiotensinogen
Definition
a plasma protein that splits off angiotensin I when acted on by renin
Term
anterior lobe
Definition
the adenohypophysis or pars distalis
Term
antidiuretic
Definition
also known as vasopressin, ADH increases the rate of recovery of water from collecting ducts in the kidney; thus, it promotes water conservation and the production of scanty, concentrated urine.
Term
arachidonic acid
Definition
a fatty acid present in plasma membranes
Term
atrial natriuretic factor (ANF)
Definition
a peptide hormones released by the muscle fibers of the atria that, along with ADH and aldosterone, regulates kidney functions
Term
basal metabolic rate
Definition
the rate of energy use that is unrelated to specific body activities such as eathing, exercise, or,keeping warm
Term
calcitonin
Definition
a hormone secreted by the throid that stimulates bone calcification
Term
Calcium ion (Ca++)
Definition
An important second messenger involved in activating secretion in exocrine and endocrine glands
Term
Calmodulin
Definition
The major calcium binding protein for smooth muscle and none muscle cells
Term
Carrier proteins
Definition
specific proteins that carry steroid hormones in the blood as complexes
Term
Cell surface receptors
Definition
Hormones are recognized by these membrane-spanning receptors that then generate an intracellular second messenger
Term
Cholecystokinin (CCK)
Definition
Inhibits gastric emptying and stimulates gallbladder contractions to increase delivery of digestive enzymes to the duodenum
Term
Colloid
Definition
A protein matrix that acts as a reservoir for iodine accumulated in the thyroid from the blood
Term
Cushing's syndrome
Definition
A condition in which excessive adrenal activity is generally the result of excessive secretion of ACTH
Term
Cyclic adenosine monophosphate (cAMP)
Definition
The cyclic nucleotide that acts as a second messenger
Term
Diabetes mellitus
Definition
failure of the pancreas to secrete adequate insulin
Term
Diacylglycerol
Definition
A signaling substance that is a hydrophobic molecules that diffuses freely with in the plasma membrane and acts on a specific family of protein kinases (C kinases) distinct from that affected by cyclic nucleotides
Term
Dihydrotestosterone
Definition
A gonadal male hormone
Term
Endocrine gland
Definition
A structure specialized for production and secretion of hormones
Term
Endorphins
Definition
Peptide hormones involved in the process by which the body modulate his own pain sensitivity
Term
Enkephalins
Definition
Peptide hormones involved in the process by which the body modulate its own pain sensitivity
Term
Epinephrine
Definition
Secreted by the adrenal medulla a catecholamine that is an important hormone along with cortisol and glucagon of the post absorptive state
Term
Erythropoietin
Definition
A hormone that acts on the hematopoietic tissue of flat bones to stimulate the production of red blood cells
Term
Estrogens
Definition
The gonadal female sex hormone
Term
Exopthalmos
Definition
A protrusion of the eyes due to hyper thyroidism
Term
Gastrin
Definition
A mediator secreted by the stomach that stimulates secretion of effort and pepsin by the gastric mucosa
Term
Glucagon
Definition
Secreted by the pancreas a hormone along with cortisol and epinephrine that is important in the postabsorptive state
Term
Glucose tolerance test
Definition
A test for the clinical diagnosis of diabetes mellitus in which the patient fast until the post absorptive state is reached then ingests a glucose meal
Term
Glucose dependent insulinotropic hormone
Definition
A hormone released in response to the appearance of a carbohydrate meal in the duodenum and stimulates an early release of insulin in advance of the appearance of the glucose in the blood
Term
Hematocrit
Definition
The fraction of blood volume that is red blood cells
Term
Human growth hormone HGH
Definition
a hormone that plays a central role in the control of growth throughout the body
Term
Hypertension
Definition
Elevated blood pressure
Term
Hypocalcemia
Definition
A drop in plasma calcium
Term
hypokalemia
Definition
Depressed plasma potassium
Term
Hypothalamopituitary portal system
Definition
A special variety of blood circulation that involves two sets of capillaries connected by one or more portal veins
Term
Hypothyroid cretinism
Definition
A form of intellectual disability caused by early thyroid deficiency
Term
Hypovolemia
Definition
A decrease in the volume of the circulating blood
Term
Islets of Langerhans
Definition
Endocrin sales in bed in the exocrine tissue that secrete three major protein hormones: glucagon, insulin and somatostatin
Term
leptin
Definition
A protein hormone released by adipose cells in proportion to their stored fat content that acts on the central nervous system to suppress appetite
Term
Melanocyte stimulating hormones
Definition
A family of hormones included in the POMC sequences that are important in animals that change color but apparently have no normal function in humans
Term
Melatonin
Definition
A hormone secreted by the pineal gland that plays an important role in synchronizing the 24 hour cycle of the body in promoting rest during darkness
Term
Motilin
Definition
A hormone that stimulates periodic wave of contraction in the post absorptive gut which we identify as stomach growling
Term
Myxedema
Definition
A disorder of the body fluids distribution caused by excessive production of mucopolysaccharides in tissue
Term
Neurohypophysis
Definition
An extension of the hypothalamus that contains the axon terminals of neurosecretory hypothalamic neurons
Term
Neurosecretory cells
Definition
Neurons who synapses release substances that passed into the blood and act as hormones
Term
Noradrenaline
Definition
The catecholamine norepinephrine
Term
Nuclear receptor
Definition
Structure within the cell that interacts with mainly steroid hormones
Term
Oxytocin
Definition
The octapeptide hormone primarily associated with labor and breastfeeding
Term
Parathormone PTH
Definition
A hormone of the parathyroid that regulate bone growth and plasma calcium levels
Term
Paraventricular nucleus
Definition
Releases the octapeptide hormone oxytocin
Term
Peptides
Definition
A small protein that may range from a few as 3 amino acids to about 30 amino acids
Term
Phosphodiesterase
Definition
An enzyme that converts cAMP to an inactive form
Term
Phospholipase C
Definition
A membrane-bound enzyme that splits a small fraction of the plasma membrane phospholipid (phosphoinositol) into two signaling substances: inositol triphosphate (ITP or IP3) and diacylglycerol
Term
Placental lactogen
Definition
A hormone that prepares breasts for lactation and mobilizes maternal nutrient uptake by fetus
Term
Posterior lobe
Definition
The neurohypophysis or pars nervous of the pituitary gland
Term
Posttranslational processing
Definition
A process that snips the prohormone's with sequences at various points to yield the shorter sequences of the various hormones
Term
Thyroxine
Definition
One of the two main hormones secreted by the thyroid
Term
Triiodothyronine (T3)
Definition
A thyroid hormone that has 3 (T3) atoms of iodine bound to the 2 benzene rings of each hormone molecule
Term
Tropic hormones
Definition
Hormones that control the function of other endocrine glands
Term
Troponin
Definition
The calcium binding protein in skeletal and cardiac muscle
Term
Tyrosine
Definition
An aromatic amino acid from which the catecholamines epinephrine and norepinephrine and the thyroid hormones triiodothyronine (T3) and tetraiodothyronine (T4) are derived
Term
Vasopressin
Definition
an antidiuretic hormone
Term
Norepinephrine
Definition
The major transmitter chemical released by sympathetic postganglionic fibers
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