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Definition
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| Binding of hormone to a receptor tyrosine kinase causes all of the following except |
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Definition
| hydrolysis of GTP bound to Ras. |
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Definition
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Term
| In which of the following double-mutant flies will R7 photoreceptors develop normally? |
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Definition
| constitutively active MAPK and inactive Ras |
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Term
| Serum response factor (SRF) is phosphorylated by |
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Definition
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Term
| By what mechanism does PI-3 phosphate promote activation of protein kinase B (PKB)? |
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Definition
| Recruiting PKA to the plasma membrane, inhibting the PH domain, recruiting PI-3 to the plasma membrane |
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Term
| Which of the following are enzyme pairs that catalyze opposite reactions? |
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Definition
| PI-3 kinase and PTEN phosphatase |
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Term
| Which of the following signaling pathways can be activated by cytokines? |
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Definition
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Term
| Latent TGF beta is converted to mature TGF beta by |
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Definition
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Term
| A loss-of-function mutation in which of the following would inhibit TGF? signaling? |
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Definition
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Term
| A gain-of-function mutation in which of the following would promote malignancy in cells whose proliferation is inhibited by TGF?? |
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Definition
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Term
| Which of the following receptors binds TGF?? |
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Definition
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Term
| Which of the following contain(s) an SH2 domain? |
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Definition
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Term
| Which of the following is a protein kinase? |
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Definition
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Term
| Binding of erythropoietin to its extracellular receptor engages which of the following signaling pathways? |
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Definition
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Term
| All genes regulated by PKA contain a cis-acting DNA sequence that binds to the phosphorylated form of a transcription factor called |
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Definition
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Term
| In the NF-KappaB signaling pathway, which of the following molecules is downstream of I-?B kinase? |
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Definition
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Term
| Which of the following is cleaved by regulated intramembrane proteolysis (RIP)? |
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Definition
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| NF-kappa-B signaling is important in |
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Definition
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