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Lecture 5
Patho Exam 1
40
Nursing
Graduate
09/20/2015

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Term
Colonization
Definition
Microogranisms existing in reservoirs, animals, or another human. Microorganisms adhere to tissue through specific surgace receptors.
Term
Invasion period
Definition
Invade surrounding tissues by evading the host's defense mechanisms
Term
Endogenous pyrogens
Definition
Fever causing agent produced by leukocytes in the body
Term
Exogenous pyrogens
Definition
Fever causing agent of external origin (e.g bacterial endotoxin)
Term
Infectivity
Definition
Ability of the infectious agent to enter host and replicate
Term
Virulence
Definition
Capacity of infection to cause a sever disease (potency)
Term
Commensalism
Definition
Benefits only the microorganism, no harm to the human
Term
Biofilm
Definition
Complex mutlicellular masses where microogranisms frequently exist in humans
Term
Mold
Definition
Multicellular branching (Canida albicans, dimorphic both mold and yeast)
Term
Antigenic shift
Definition
Influenza undergoes antigenic shift. Shifts occur in animals coinfected by a human and an avian strain of influenza. Segments of the genome undergo recombination during which the human virus obtains a new HA or NA antigen. Can result in a major pandemic.
Term
AIDS
Definition
(Acquired Immunodeficiency Syndrome). Most notable form of acquired immune deficiency caused by an infectious agent. AIDS is a viral disease caused by HIV.HIV deplets immune system (helper T cells).
Term
Integrase
Definition
An enzyme produced during HIV life cycle. Integrase integrates viral HIV DNA in to host DNA.
Term
MRSA
Definition
(Methicillin-resistant Staphylococcus aureus) S. aureus can cause numerous diverse diseases. Each strain has a mixture of toxins. MRSA is a type of S. aureus that has developed resistance to antibiotics.
Term
Toxoid
Definition
A chemically modified toxin from a pathogenic microorganism, which is no longer toxic but is still antigenic and can be used as a vaccine
Term
Incubation Period
Definition
Period of initial exposure to onset of first symptoms
Term
Convalescence
Definition
Recovery occurs and symptoms decline, the disease is fatal and the patient dies, the infection is over, or the disease has a period of latency.
Term
Communicability
Definition
Ability of infection to spread
Term
Pathogenicity
Definition
Ability of infection to produce disease
Term
Symbiosis
Definition
Interaction between two different organisms living in close physical association, typically to the advantage of both
Term
Opportunism
Definition
A microorganism that does not ordinarily cause disease but under certain circumstances (for example impaired immune responses resulting from other disease or drug treatment), becomes pathogenic). --> Kaposi Sarcoma/Herpes simplex virus during HIV latency period
Term
Exotoxin
Definition
A toxin released by a living bacterial cell into its surroundings
Term
Yeast
Definition
Single cell, reproduce by budding. (Canida albicans, dimorphic because it is both mold and yeast)
Term
Recombination
Definition
Rearrangement of genetic material, especially by crossing over in chromosomes or by the artificial joining of segments of DNA from different organisms. Occurs in HIV life cycle.
Term
Retrovirus
Definition
A group of RNA viruses that insert a DNA copy of their genome into the host cell in order to replicate, e.g., HIV
Term
Bacteriostatic drug
Definition
A drug that inhibits the growth of the microorganism until it destroyed by the body's own protective mechanisms.
Term
Vaccine
Definition
A substance used to stimulate the production of antibodies and provide immunity against one or several diseases, prepared from the causative agent of a disease, treated to act as an antigen without inducing the disease.
Term
Attenuated virus
Definition
A weakened, less vigorous virus. An attenuated virus may be used to make a vaccine that is capable of stimulating an immune response and creating immunity, but not of causing illness
Term
Prodormal stage
Definition
Initial stage, characterized by first symptoms
Term
Fever
Definition
Increased temperature due to body's innate immune response.
Term
Immunogenecity
Definition
Ability to produce an immune response
Term
Toxigenicity
Definition
Ability to produce toxins
Term
Mutualism
Definition
Beneficial to both host and bacteria
Term
Pili
Definition
Typically on gram negative bacteria. Pili determines where a bacterium can go and attach
Term
Endotoxin
Definition
A toxin that is present inside a bacterial cell and is released when the cell disintegrates
Term
Dimorphic fungus
Definition
Is both yeast or mold. E.g Canida albicans
Term
HIV
Definition
Human Immunodeficiency virus. A retrovirus that causes AIDS by infecting helper T cells of the immune system.
Term
Reverse transcriptase
Definition
Enzyme used to generate complementary DNA from an RNA template. Common in retroviruses.
Term
Bacteriocidal drug
Definition
Drug that kills the bacteria.
Term
Passive immunotherapy
Definition
Primary defense system that evolved first, at birth. Involves antibodies, cytokines, T cells and macrophages. The objective of passive immunotherapy is to provide immediate protection.
Term
Dermatophyte
Definition
Fungi that can cause infections of the skin, hair, and nails due to their ability to utilize keratin.
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