Very sedating antihistamine

Included in many over the counter sleep aides

Very sedating antihistamine

Used as a sedative

Sedating antihistamine

Included in over the counter sleep aides

Used to treat some forms of parkinsonism

Used to decrease respiratory secretions

Sedating antihistamine

Used to treat motion sickness and vertigo

Sedating antihistamine

Used in cough medicines

Sedating antihistamine

Used to treat motion sickness and vertigo

H2 antagonist

Reduce gastric acid sectretion

All sorts of side effects: antiandrogen efffect = gynecomastia, decreased libido, sexual problems

Used to treat masculinization (hirsutism) in females

Used to treat Zollinger Ellison Syndrome (gastrin secreting tumor)

Inhibits hepatic drug metabolizing enzymes resulting in all sorts of other drug metabolism issues

H2 Antagonist

Reduces gastric acid secretion

Used to treat Zollinger Ellison Syndrome (gastrin secreting tumor)

H2 Histamine antagonist

Reduces gastric acid secretion

Used to treat Zollinger Ellison Syndrome (gastrin secreting tumor)

H2 histamine antagonist

Reduces gastric  acid secretion

Used to treat Zollinger Ellison Syndrome (gastrin secreting tumor)

NOT ON OUR LIST - LONG DISCUSSION IN NOTES

Terfenadine/Astemizole + Erythromycine/Ketoconazole/Itraconazole = life threatening arrhythmias (torsades de pointers)

Terfenadine is normally metabolized in liver from toxic prodrug to active form, however when other drugs present (e.g. erythromycin) the prodrug form stays in the circulation and can cause arrthmias