Often gram positive cocci such as streptococci and staphylococci associated with infective endocarditis

Caused by Borrelia burgdorferi, same insect vector as with Babesia microti agent of Babesiosis, deer tick Ixodes dammini/I. scapularis, erythema migrans chronicum ring like rash around tick bite, fever, arthalgias, later neuroborreliosis or destructive migratory arthritis

Giant cell myocarditis, Chagas’ disease, South American trypanosomiasis

Bite on face of child with unilateral periorbital edema called Romana’s sign, Venezuela, Brazil, amastigote forms of Trypanosoma cruzi in cardiac myofibers with mixed inflammatory infiltrate, trypomastigotes in peripheral blood smear, cause of dilated cardiomyopathy with congestive heart failure

Sarcoidosis with noncaseating granulomas