-lymphocytes that survive

-bind weakly to self-antigens

-lymphocytes that are eliminated

-bind strongly with self-antigen

-don't recieve any receptor/ligand interaction

-hematopoietic stem cell

-becomes B cell

-B cell precursor experiences somatic recombination

-expresses membrane bound Ig

-membrane bound receptors are tested

-cell becomes mature naive

-becomes activated by interaction with antigen

-activated B cell becomes plasma cell

-early pro-B cell

-late pro-B cell

-large Pre-B cell

-smalle pre-B cell

-immature B cell

-mature naive B cell

-H chain gene rearrangement

-DJ rearrangments on both chromosomes

-H chain gene rearrangement

-VDJ rearrangment on first chromosome (productive)

-VDJ rearrangement on second chromosome (cell loss)

-L chain gene rearrangement

-rearrange K gene on first chromosome