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Definition
| ○ Any chemical that can affect living processes |
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Term
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Definition
A drug cannot give cells new functions
A drug can enhance/mimic or block an action of the body’s molecules |
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Definition
Prescription
Non-prescription (OTC)
Herbals |
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Definition
| The study of drugs and their interaction with living systems |
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Term
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Definition
Physical and chemical properties of a drug
Biochemical and physiologic effects |
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| Pharmacology gives us jnowledge of how drugs are: |
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Definition
Absorption
Distribution
Metabolism
Excretion |
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Term
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Definition
| the study of drugs in humans |
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Term
| Clinical Pharmacology includes: |
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Definition
ncludes the study of drugs in patients as well as healthy volunteers
Major portion of drug research and development |
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| • Therapeutics (Pharmacotherapeutics) |
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Definition
the use of drugs to:
Diagnose disease
Treat disease
Prevent disease
Prevent pregnancy |
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| Properties of an Ideal Drug |
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Definition
Safe
Effective
Selective
Effectiveness
Elicits the response for which it is given
(The drug does what it is supposed to do!) |
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Term
| This is the most important property a drug can have |
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Definition
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Term
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Definition
| cannot produce harmful side effects even in very high doses over an extended period of time. |
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Term
| Is there suich thing as safe drugs, t or f |
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Definition
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Definition
Using lowest therapeutic dosage
Avoidance of drug interactions |
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Definition
| • Elicits only the response for which it is given |
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Term
| An entirely selective drug would produce |
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Definition
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| there is no such thing as a selective drug, true or false? |
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Definition
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Term
| All medications cause side effects, true or false? |
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Definition
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Term
| • Additional Properties of an “Ideal Drug” |
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Definition
• Reversible action
• Predictability
• Ease of administration
• No drug interactions
• Low cost
• Chemically stable
• Possession of a simple generic name |
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Term
| • Why a simple generic name? |
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Definition
• Generic names are usually complex and difficult to remember or pronounce
• Acetaminophen: Tylenol
• Ranitidine: Zantac
• Atorvastatin Lipitor
• Ezetimibe Zetia |
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Term
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Definition
| • Maximum benefit/Minimum harm |
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Term
| • Intensity of Drug Responses are Dependent upon: |
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Definition
Administration
Pharmacokinetics
Pharmacodynamics |
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| What needs to be verified before Administration? |
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Definition
• Dose size
• Route
• Timing
• Medication errors and poor patient adherence can decrease the safety and efficacy of any drug. |
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Term
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Definition
| Movement of a drug across body membranes to reach its target organ |
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Term
| 4 major pharmacokinetic processes |
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Definition
Drug absorption
Drug distribution
Drug metabolism
Drug excretion |
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Term
| • These 4 processes can be thought of as the impact of the body on drugs |
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Definition
Drug absorption
Drug distribution
Drug metabolism
Drug excretion |
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