Term
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Definition
| The "coded" mRNA-dependent synthesis of proteins |
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Term
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Definition
-base triplets in mRNA
- 5'-->3'
some stop codons:
UGA; UAA; UAG
Trp codon:
UGG
Met codon:AUG |
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Term
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Definition
(CODON)
- 3 base sequence that specify a specific AA |
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Term
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Definition
| - multiple codons can specify the same AA |
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Term
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Definition
| - a single codon specifies only one AA |
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Term
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Definition
| - once a codon starts, there is only one correct "reading frame" of triplets |
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Term
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Definition
| - once initiated, bases are "read" until a stop codon is reached |
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Term
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Definition
- the theory that the third position (3'-->5') on the anti codon "wobbles"
- this results in flexibility in codon:anticodon recognition
- allows for translation with tRNA less than 64 |
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Term
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Definition
Formation of Aminoacyrl-tRNA
Aminoacyrl tRNA syntheases - no mistakes
- one or more per amino acid
- tRNA/anticodon recognition elements
- some with proofreading ability |
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Term
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Definition
IF-1: blocks acceptor site until first aa-tRNA comes along
IF-3: prevents premature binding of 30S subunit to 50S subunit |
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Term
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Definition
| A sequence of bases upstream from the AUG codon that binds to the 30S subunit to indicate the presence of the first AUG codon |
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Term
| CONSENSUS SEQUENCE FOR SHRINE-DALGARNO |
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Definition
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Term
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Definition
-IF-2 binds to 30S and IF-1 is displaced
- promotes fmet-tRNA binding to P site
GTP is hydrolyzed...
- IF-1 & IF-3 fall away and 50S binds to 30S |
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Term
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Definition
major component of large ribosomal subunit
- catalyzes peptide bond formation |
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