Shared Flashcard Set

Details

Lecture 14
Lecture 14 material
8
Immunology
Undergraduate 4
05/06/2013

Additional Immunology Flashcards

 


 

Cards

Term
IgM function
Definition

-blood

-first responder

-first to be expressed because don't need class switching

-have relatively low affinity

Term
IgD function
Definition

-membrane bound

-unknown function

Term
IgG function
Definition

-blood, intercellular

-4 subclasses

-high affinity/avidity antigen binding site

-good viral/toxin/bacterial neutralizer

-good opsonizer

-activates complement system

Term
IgE function
Definition

-bound to mast cells

-lowest level in blood

-if encounter complementary antigen, mast cell gets triggered to release histamines

-control parasites

Term
IgA function
Definition

-epithelial and mucosal surfaces, blood

-principle Ig in secretions

-dimer on mucosal surfaces

-monomer in tissue, lymph nodes and blood

-less effective at opsonization than IgG

-good neutralizer

Term
measuring humoral immunity
Definition
-hemagglutinin assay
Term
hemagglutinin assay method
Definition

-make serial dilution of test serum

-add constant amount of virus to each well

-add constant amount of red blood cells to each well

-incubate

-read results

-endpoint titer is reciprocal of last serum dilution which prevents agglutination

Supporting users have an ad free experience!