Term
|
Definition
| Shows lots of protein variation. Heterozygous if there are two bands |
|
|
Term
|
Definition
| comparisons of hemoglobin across numerous taxa indicated rate of substitution was pretty constant across different lineages |
|
|
Term
|
Definition
| most polymorphism and most substitutions are neutral |
|
|
Term
| Probability that a newly arising neutral allele goes to fixation |
|
Definition
|
|
Term
| Synonymous (silent) substitutions |
|
Definition
| A change in the DNA sequence that does not alter the amino acid encoded (due to degeneracy of code) |
|
|
Term
| Non-synonymous (replacement) substitutions: |
|
Definition
| A change in the DNA sequence that does alter the amino acid encoded |
|
|
Term
|
Definition
| more polymorphisms in small populations |
|
|
Term
| The neutral theory problems |
|
Definition
Polymorphism levels are too low
Molecular clock ticks on a per year, not a per generation time scale
Variation across lineages in substitution rate is greater than predicted |
|
|
Term
| Symmetric overdominant selection |
|
Definition
Fitness is as follows:
B0B0 1 - s
B0B1 1
B1B1 1 - s |
|
|
Term
|
Definition
| Tremendous amount of protein variation |
|
|
