boswellic acid (looks like a steriod)

(+)asthma, antiinflamm. inhibit LTB4

caps-300mg/day tid for bronchospasms

(-)gi upset

forskolin

10-18% or 10mg in powder inhaled

iv:prophylactic b4 tracheal intubation

(+)asthma, relive constriction

inhib hiastamine release from mast, inhibit LTB4, increase cAMP

(-)tachy,additive w bronchodilator drugs

seed oil oral(+)acute resp. distress syndrome

flowers/leaves (+)fever, cough, lung inflamm.

GLA metabolized to DGLA converted to PGE1

asthma: 2g of GLA for 12 mo.

suppresses LTB4

(-)gi upset

Khella

Ammi visnaga

khellin (furanocoumarin);starting deriv. for nifedipine

(+)asthma, allergic rhinitis

inhaler or eyedrop(what?)

(+)angine; 300mg/day

Butterbur

Petasites hybridus

(+)asthma, allergic rhinitis

eremophinolides: sesquiterpene lactones (major)

pyrrolizidine alkaloid (minor),

petastin: anti inflamm., 8mg 3-4x/day, allergic rhinitis

(-)not for internal use bc of alkaloids, must be less than 1ug daily

Echinacea

(+) URI, UTI, slow healing wounds (topical)

echinacoside & caffeic acid derivs

6.78mg , 95%herb, 5% root

20 drops q2 hrs, tincture, teas

(+)cold, URI, anti viral

triterpenoids saponins isoflavones

increase IgA & IgG & IL2

(-)28g/day cause immune supproession

oral, powder, soup

Spirulina

blue algae

Athrospira platensis

(+)PMS, anxiety, stimulate immune system

C. phycocyanin (anti inflam.); increase iL1 and macrophages

(-)contamination w/ Microcytis aeruginosa causes: jaundice, thirst, death,

(-)D-D w/ immunosuppressive drugs, little data

Angelica sinensis

Dong Quai

(+)menopause, PMS, antitumor

(-)coumarins: sunburn, D-D interactions w/ anticoags

American Mistletoe

Phoradendrom leucarpum

(+)increase BP, uterine & GI contractions

(-)phoratoxins: HTN or hypoTN, brady, delerium

similar to cobra venom: vasoconstriction, cardiac arrest

kelp

Fucus vesiculous

(+)blood cleansing, anti-HIV, antiox

(+)fucoidan: antiviral

(-)D-D w/ thyroid meds & iodine

acetyl-11-keto-beta-boswellic acid

From: Boswellia, Boswellia serrata

Inhibits the release of LTB4

Forskolin

From: Coleus, Coleus forskohlii

Gamma-linolenic acid (GLA)

From: Borage, Borago officinalis

Khellin

From: Khella, Ammi visnaga (L.) Lam.

echinacoside

From: Echinacea, E. pallida Nutt./E. purpurea Moench.

Angelica root (DONG QUAI), Angelica sinensis