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LATG 14: Common Health Problems of Laboratory Animals
AALAS
185
Medical
Professional
06/24/2018

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Cards

Term
Which species are carriers of B. bronchiseptica and so should not be housed in the same areas as guinea pigs?
Definition
Rabbits
Term
A goat that is staggering and kicking their belly most likely has which condition?
Definition
bloat
Term
Guinea pigs housed on wire floors may have inflamed, swollen, and painful feet due to infection with which organism?
Definition
Staphylococcus aureus
Term
To prevent ruminants from suffering positional bloat during a surgical procedure, which measure is typically taken during the procedure?
Definition
Placement of a rumen tube
Term
Which term is used for the stones that can be found in the bladders of some cats?
Definition
Cystuli
Term
Which agent has been identified as the cause of scaly skin disease in athymic nude mice?
Definition
Corynebacterium bovis
Term
Wild-caught animals are likely to carry which ectoparasites?
Definition
Fleas
Ticks
Mites
Term
Which of the following is an indication an animal has malocclusion?
Definition
Weight loss
Wetness of the chin and forepaws
Excess salivation
Term
How is rabies most often transmitted?
Definition
bite
Term
An early sign of infestation with mites, fleas, and ticks is:
Definition
Excessive scratching
Term
An early sign of infestation with mites, fleas, and ticks is:
Definition
Excessive scratching
Term
Once clinical signs are observed, rabies is almost always fatal.
Definition
True
Term
Treatment for diarrhea often includes anticholinergic and antisecretory drugs.
Definition
True
Term
What is the common name for a gastric trichobezoar?
Definition
Hairball
Term
The use of antibiotics that are mainly effective against gram positive organisms should be avoided in guinea pigs.
Definition
true
Term
Fleas do not infest reptiles.
Definition
true
Term
Among all animals used in research, which are at the greatest risk for contracting rabies?
Definition
Wild-caught animals
Term
Helicobacter spp. are most commonly diagnosed with which technique?
Definition
Polymerase chain reaction
Term
What clinical sign would suggest that young mice may have epizootic diarrhea of infant mice (EDIM)?
Definition
Yellow stains around the base of the tail
Term
Which system is primarily affected by Mycoplasma pulmonis?
Definition
Respiratory
Term
Mycoplasma pulmonis is rarely seen among laboratory rats.
Definition
True
Term
An immunodeficient mouse that has contracted mouse norovirus may have
Definition
pneumonia, hepatitis, and meningitis.
Term
Infection with Mycoplasma pulmonis can result in a severe head tilt.
Definition
true
Term
Helicobacter bilus or Helicobacter hepaticus causes inflammatory bowel disease in SCID mice.
Definition
Helicobacter bilus
Term
Which statement about Corynebacterium bovis is FALSE?
It is highly virulent and persistent in the environment.
Chlorine dioxide is effective for decontamination of C. bovis.
It causes a hyperkeratotic dermatitis.
Transmission can be reduced by using microisolation-type caging.
Definition
Transmission can be reduced by using microisolation-type caging.
Term
Syphacia spp. can be detected by finding eggs on the perineum of the affected animal.
Definition
True
Term
The female Aspiculuris tetraptera pinworm lays its eggs on the perineum; the Syphacia lays its eggs in the animal's colon.
Definition
false
Term
Which of the following is NOT a characteristic of epizootic diarrhea of infant mice (EDIM) that could affect research results?
Behavior abnormalities
Increased mortality
Reduced weight gain
Greater susceptibility to other infections
Definition
Behavior abnormalities
Term
Sialodacryoadenitis is which type of virus?
Definition
Coronavirus
Term
The most common method used to detect the presence of mouse hepatitis virus (MHV) in a colony is serology testing of sentinels and colony animals.
Definition
true
Term
Mouse parvovirus causes severe diarrhea.
Definition
false, almost always subclinical
Term
Idiopathic ulcerative dermatitis is caused by protozoan infestation.
Definition
false, origin is unknown
Term
Adult mice infected with epizootic diarrhea of infant mice (EDIM) have watery, yellow stools.
Definition
false, Adult mice infected with EDIM show no clinical signs.
Term
Pododermatitis is also known by what name?
Definition
Bumblefoot
Term
Pasteurellosis is spread by which route(s) of transmission?
Definition
Direct contact
Aerosol
Term
Which of the following causes coccidiosis?
Protozoa
Parvoviruses
A bacterial toxin
Pinworms
Definition
Protozoa
Term
Tyzzer's disease is effectively treated with sulfa drugs.
Definition
false There is no effective treatment for Tyzzer's disease.
Term
5. Multiple Choice/Single Answer - select one answer
Which is the best method of preventing bumblefoot?
Definition
Use of clean, dry substrate
Term
Increased porphyrin secretion from the Harderian glands or high humidity causes which of the following problems in gerbils?
Definition
Nasal dermatitis
Term
Sore nose in gerbils is caused by which kind of pathogen?
Definition
Bacteria
Term
What is the best method of controlling pasturellosis in rabbits?
Definition
Purchase Pasturella-free rabbits.
Term
9. Multiple Choice/Single Answer - select one answer
Which of the following statements regarding bacterial pneumonia in guinea pigs is true?
Definition
It is often associated with Bordetella bronchiseptica and Streptococcus pneumoniae.
Term
Lymphocytic choriomeningitis virus (LCMV) is a zoonotic organism found in mice and hamsters.
Definition
true
Term
In which organ of the body are insulinomas found in ferrets?
Definition
pancreas
Term
Which of the following clinical signs in NOT associated with Aleutian disease in ferrets?
Lethargy
Ocular discharge
Weight loss
Tremors
Definition
Ocular discharge
Term
Which of the following is the BEST way to prevent canine distemper in ferrets
Definition
Vaccination
Term
Which statement is a correct summary of how aplastic anemia develops in female ferrets?
If females are bred to much younger males, estrogen levels increase rapidly and lymphocytes destroy the red blood cells.

If intact females are not allowed to breed, estrogen levels remain high and the imbalance affects the bone marrow.

If females are bred after the age of 5 years, estrogen levels are too low and breeding dangerously reduces hemoglobin levels.

Sterilized females have very low estrogen levels and, if housed with males, platelet levels rapidly decrease.
Definition
If intact females are not allowed to breed, estrogen levels remain high and the imbalance affects the bone marrow.
Term
Which of the following is a sign of canine distemper in ferrets?
Diarrhea
Anemia
Dyspnea
Ataxia
Definition
Ataxia
Term
An ELISA test can be used to diagnose heartworm infection in dogs.
Definition
true
Term
Where are Dirofilaria immitis (heartworms) found in a dog's body?
Definition
Right atrium and pulmonary artery
Term
Cleaning and drying the ear canal should always be done for dogs with externa otitis.
Definition
true
Term
Dogs suffering with parvovirus typically have a temperature of at least 40 degrees Celsius.
Definition
false,Puppies usually have a high body temperature, but older dogs do not.
Term
Medication that raises the pH of the urine is used to treat feline lower urinary tract disease.
Definition
false,Medication that lowers the pH of the urine is used to treat feline lower urinary tract disease.
Term
What is the condition in cats characterized by frequent, painful, or difficult urination; hematuria; and straining?
Definition
Feline lower urinary tract disease
Term
Excessive grooming in cats can lead to which of the following?
Definition
Gastric trichobezoars
Term
Radiographs are generally not useful in diagnosing tuberculosis in nonhuman primates.
Definition
true
Term
Which human virus is a retrovirus that is said to have its origin in nonhuman primates?
Definition
Human immunodeficiency virus (HIV)
Term
An employee who works with nonhuman primates and has been exposed to measles outside of the facility should notify the animal facility supervisor as soon as possible.
Definition
true
Term
n most cases, nonhuman primates contract tuberculosis through contact with which of the following?
Definition
Infected humans
Term
All personnel having contact with nonhuman primates should be vaccinated against which zoonotic contagious disease?
Definition
Measles
Term
Which zoonotic viral disease often remains asymptomatic in infected macaques and can be fatal in humans?
Definition
B virus
Term
Nonhuman primates are highly susceptible to which zoonotic respiratory disease?
Definition
Tuberculosis
Term
A bite kit in a facility housing primates should contain which of the following components?
Definition
Viral culture swabs
Sample collection tubes
Disinfectant
Wound cleaning instructions
emergency room information card for Doctor
Term
Intradermal tuberculin testing is used to test nonhuman primates for tuberculosis.
Definition
True
Term
To test nonhuman primates for tuberculosis, the tuberculin is injected intradermally in which part of the body?
Definition
Upper eyelid
Term
Laminitis is a condition affecting the:
Definition
Hooves
Term
To reduce the chance of contracting orf, which precaution should always be taken by personnel handling sheep?
Definition
Wear gloves.
Term
To reduce the chance of contracting orf, which precaution should always be taken by personnel handling sheep?
Definition
Wear gloves.
Term
Coxiella burnetii can easily be eliminated from an animal facility by regular disinfection of the area where ruminants are kept.
Definition
false
Term
Which of the following is a common cause of rumen stasis?
Definition
Sudden change in the diet
Term
Which ruminants present the greatest risk for transmitting Q-fever to humans?
Definition
Pregnant or postpartum females
Term
Orf usually affects humans on their:
Definition
hands
Term
How is rumen stasis generally treated?
Definition
Administration of warmed saline and electrolytes
Term
Orf is also known as contagious erythremia.
Definition
False,
Orf is also known as contagious ecthyma.
Term
Contagious ecthyma is a zoonotic disease that can be life threatening to humans.
Definition
false, usually causes a painful blister at point of infection that usually resolves in 7-10 weeks
Term
Coxiella burnetii is the causative agent for which disease?
Definition
Q fever
Term
Q fever is found only in sheep.
Definition
false
Term
Which of the following symptoms may be due to infection with Pasteurella multocida?
Septicemia
Respiratory disease
Mastitis
Definition
all the above
Term
Humans with Q fever usually have conjunctivitis and blisters around their nose and mouth.
Definition
false,Q fever in humans may be asymptomatic or there may be mild symptoms resembling influenza.
Term
Pasteurellosis may cause septicemia, an infection of the bloodstream.
Definition
true
Term
Q fever spreads mainly by inhalation of aerosol.
Definition
true
Term
In rumen stasis, a change in the pH of the rumen results in what of feed.
Definition
putrefaction
Term
1. True/False - select one answer
Porcine circovirus may be transmitted by the aerosol, fecal-oral, and contact routes.
Definition
true
Term
What is the cause of malignant hypothermia in swine?
Definition
Gene mutation
Term
Which health problem would cause a pig to appear oblivious to its surroundings and to have seizures?
Definition
Salt toxicity
Term
Which of the following pathogens causes velvet disease?
Definition
Piscinoodinium pillulare
Term
Ich is caused by which pathogen?
Definition
Ichthyopthirius multifilis
Term
Which disease causes lethargy and excessive mucus and white spots on the skin of fish?
Definition
ich
Term
Which agent is associated with red leg in amphibians?
Definition
Aeromonas hydrophila
Term
A bacterial septicemia that occurs frequently in frogs and that can cause erosion of the toes, feet, and jaws is called:
Definition
red leg
Term
Atabrine and sea salt baths are used in the treatment of velvet disease in fish.
Definition
ture
Term
Chytridiomycosis can lead to a loss of the righting reflex in affected amphibians.
Definition
true
Term
Which of the following diseases of aquatic species is caused by a fungus?
Definition
Chytridiomycosis
Term
An infection with Pseudocapillaroides xenopi is called:
Definition
cutaneous capillariasis.
Term
Cutaneous capillariasis can be treated successfully with bactericidal antibiotics.
Definition
false,Cutaneous capillariasis can be treated successfully with anthelmintics.
Term
Which fish disease is also known as fin rot?
Definition
Bacterial gill disease
Term
Xenopus with hard bloat can be successfully treated with Epsom salt baths.
Definition
false, Xenopus with soft bloat can be successfully treated with Epsom salt baths.
Term
The difference between hard and soft bloat in amphibians is where the excess fluid is held in the body.
Definition
Yes, In hard bloat, the fluid is in the body cavity; in soft bloat, the fluid is within body tissues.
Term
What makes rabbits prone to blockages caused by hairballs?
Definition
Small pyloric lumen
Term
At necropsy, which finding is most likely in an animal infected by Mycoplasma pulmonis
Definition
Scarred lungs
Term
Which disease in fish is caused by a protozoan species?
Definition
Ich
Term
What is another name for infectious tracheobronchitis in dogs?
Definition
kennel cough
Term
Which type of medication may help eliminate signs of coccidiosis?
Definition
Sulfa drugs
Term
Which of the following is NOT an effective treatment for insulinoma in ferrets?
Definition
Insulin
Term
Which type of virus is human immunodeficiency virus (HIV)?
Definition
Retrovirus
Term
Which zoonotic agent can be harbored by hamsters for an extended period of time, often without clinical signs?
Definition
Lymphocytic choriomeningitis virus
Term
What treatment is recommended for dogs diagnosed with canine parvovirus?
Definition
Intravenous fluids, antibiotics, and analgesics
Term
What is the causative agent of Tyzzer's disease?
Definition
Clostridium piliforme
Term
Helicobacter spp. are most commonly diagnosed with which technique?
Definition
pcr
Term
Which disease is characterized by fish rubbing their sides and flipping around in the corners of the tank?
Definition
Velvet disease
Term
Which disease causes lethargy and excessive mucus and white spots on the skin of fish?
Definition
Ich
Term
Which disease is often fatal in ferrets?
Definition
Canine distemper
Term
Among all animals used in research, which are at the greatest risk for contracting rabies?
Definition
Wild-caught animals
Term
The mouse norovirus is spread by which route of transmission?
Definition
fecal-oral
Term
Which is a clinical sign of coccidiosis?
Definition
Altered liver function
Term
What causes most of the illness of pasteurellosis in ruminants?
Definition
A bacterial spore
Term
Which disease may result in the sudden death of large numbers of fish in the aquaria?
Definition
Gas bubble disease
Term
What is the typical treatment for a ruminant with a severely distended, bloated abdomen?
Definition
Surgical incision of the rumen
Term
Which of the following is a major agent involved in feline respiratory disease?
Definition
Viral rhinotracheitis
Term
Which tissue type is used to test for mouse parvovirus?
Definition
Lymph node
Term
Aplastic anemia can be caused by which of the following in female ferrets?
Definition
Bone marrow suppression from high estrogen levels
Term
What is the most common sign of infection with B virus?
Definition
Oral lesions or ulcers
Term
Which of the following is the BEST way to prevent canine distemper in ferrets?
Definition
Vaccination
Term
Orf mainly affects which animals?
Definition
Sheep and goats
Term
Where are Dirofilaria immitis (heartworms) found in a dog's body?
Definition
Right atrium and pulmonary artery
Term
Peridontal disease is a bacterial infection of the _______ and the accumulation of _______.
Definition
gums, tartar
Term
What is the most common disease of freshwater fish maintained in aquaria in institutional settings?
Definition
Bacterial gill disease
Term
What should be used to clear Clostridium pilliforme from equipment?
Definition
An antisporicidal sterilant
Term
Pseudocapillaroides xenopi is what type of organism?
Definition
Nematode
Term
Which term is used for the stones that can be found in the bladders of some cats?
Definition
Uroliths
Term
Insufficient dietary fiber in rabbits can cause which of the following?
Definition
Trichobezoars
Term
Which of the following does NOT predispose a cat to be more likely to develop feline lower urinary tract disease?
A diet of mainly dry food
Little exercise
A diet containing taurine
Restricted access to water
Definition
A diet containing taurine
Term
Which mouse viral infection is considered the most widespread in facilities in the United States and Canada?
Definition
Mouse norovirus
Term
Which fish disease is also known as fin rot?
Definition
Bacterial gill disease
Term
Which swine disease can be prevented by vaccination?
Definition
Porcine reproductive and respiratory syndrome virus
Term
Which disease of rodents affects the salivary glands and the Harderian glands?
Definition
Sialodacryoadenitis
Term
What is the most common disease of freshwater fish maintained in aquaria in institutional settings?
Definition
Microsporidiosis
Term
Flavobacterium columnare
Definition
Bacterial gill disease (fin rot) is caused by
Term
Fin rot may be treated chemically with bathing affected animals in
Definition
chloramine T at 6-15 parts per million (ppm).
Term
the bacterium Aeromonas hydrophila
Definition
Red leg
Term
preventing red leg
Definition
Maintaining proper water quality and minimizing stress are the most important factors
Term
Pseudocapillaroides xenopia
Definition
common nematode found in the skin of Xenopus laevis
Term
Diagnosis red leg
Definition
Diagnosis should be confirmed by culture of Aeromonas, and the most common treatment is administration of bactericidal antibiotics
Term
Depending on the severity of the infection, clinical signs may not be apparent
Definition
Pseudocapillaroides xenopia
Term
Diagnosis is confirmed by taking skin scrapings or by euthanizing a frog and placing it under a dissecting microscope to look for small white nematodes or tunnels in the epidermis
Definition
Various anthelmintics, such as levamisole, may be used to treat frogs.
Term
Various anthelmintics, such as levamisole, may be used to treat frogs.
Definition
Various anthelmintics, such as levamisole, may be used to treat frogs.
Term
Various anthelmintics, such as levamisole, may be used to treat frogs.
Definition
Various anthelmintics, such as levamisole, may be used to treat frogs.
Term
is caused by the fungus Batrachochytrium dendrobatis
Definition
Chytridiomycosis
Term
Infection with ??? causes thickening and ulceration of the amphibian’s skin affecting hydration, respiration, thermoregulation, and osmotic balance. This results in loss of righting and flight reflexes in affected animals, convulsions, and death
Definition
chytrid or Chytridiomycosis
Term
can be diagnosed via PCR of skin swabs and treated in the aquaria with bathing in Iitraconazole antifungal medication
Definition
chytrid or Chytridiomycosis
Term
Due to the highly infectious nature frogs suspected of carrying this disease should be quarantined.
Definition
chytrid or Chytridiomycosis
Term
Bloating in Xenopus may be caused by two types of bloat
Definition
hard bloat
soft bloat
Term
If the body seems “hard” and floats at the top of the tank, it may have an
Definition
internal bacterial infection with Aeromonas hydrophila
Term
hard bloat . The “hardness” is caused by a distention of the body cavity by fluid, a condition known as
Definition
dropsy.The infection may be treated with an antibiotic, but is usually fatal.
Term
bloat, where the frog swollen with fluids within body tissues (known as edema) due to a metabolic disorder of the liver and kidneys affecting water balance
Definition
“soft” bloat
Term
To cure ----bloat, frogs may be bathed in Epsom salts (magnesium sulfate) to reduce their fluid levels as Xenopus are salt tolerant. This form of bloat may be due to overstocking in the aquaria, improper diet, or poor water quality.
Definition
“soft”
Term
an opportunistic pathogen that attacks fish when poor water quality or overfeeding conditions exist or when fish are stressed.
Definition
Bacterial gill disease (fin rot)
Term
This disease causes skin discoloration and erosive lesions, and is diagnosed by microscopic exam or culturing the lesions.
Definition
Bacterial gill disease (fin rot)
Term
disease can be prevented by maintaining good water quality, avoiding overcrowding and not feeding fish before transport
Definition
Bacterial gill disease (fin rot)
Term
how many different species of Mycobacterium are found in aquaria
Definition
4
Term
There is no effective antibiotic treatment for fish infected with
Definition
Mycobacterium
Term
This pathogen is resistant to many commonly used bactericidal agents at standard dosage rates, including chlorine bleach and quaternary ammonium compounds, so disinfection of housing systems is difficult.
Definition
Mycobacteriosis
Term
This chronic disease can be subclinical or cause symptoms such as lethargy and some deaths, especially in immunocompromised fish
Definition
Mycobacteriosis
Term
Prevention is aided by removing sick and dying fish from the tank, as it is thought to be spread through cannibalism of dead tank mates.
Definition
mycobacteriosis
Term
is a zoonotic agent which can cause nonhealing granuloma ulcers on the skin in humans. For this reason, it is recommended that staff always wear disposable gloves when working with fish; gloves should be non-powdered, and the exterior surface of the gloves should be wet before touching the fish. Always wash your hands when your procedures are done.
Definition
Mycobacteriosis
Term
is caused by the flagellate Piscinoodinium pillulare which affects the skin and the gills
Definition
Velvet Disease
Term
It is often present in aquaria, but only becomes a problem when the fish are stressed. Affected fish develop a velvety film on the skin that resembles gold- or rust-colored dust, particularly on the fins and gills. This film is easiest to see when the beam of a flashlight is directed on the fish in a darkened room
Definition
Velvet Disease
Term
Fish may remain near the water surface and have labored breathing. Treatments are atabrine (an antimalarial drug) plus sea salts.
Definition
Velvet Disease
Term
This nematode Pseudocapillaria tomentosa is an endoparasitic worm that enters the gut and causes wasting disease in fish. It may also cause intestinal cancer
Definition
Intestinal Capillariasis
Term
Diagnosis is usually by histological examination for severe chronic inflammation and the presence of the nematode
Definition
Intestinal Capillariasis
Term
Anthelmintics are effective in removing this parasite from fish and tank water. The best method of preventing this is to ensure fish are obtained from SPF suppliers and that new animals are quarantined.
Definition
Intestinal Capillariasis
Term
is the most common disease of freshwater fish maintained in aquaria in institutional settings. It is caused by the intracellular fungal parasite Pseudoloma neurophilia, which is a microsporidium
Definition
Microsporidiosis
Term
Affected animals may show emaciation and spinal curvature. Diagnosis of this is performed by histological analysis, particularly for spores.
Definition
Pseudoloma neurophilia
Term
may be treated with fumagillin (an antifungal) and by ensuring all water systems are exposed to ultraviolet light sterilization before recirculation. Bleaching embryos and removal of any sick or emaciated fish from the system can help control this parasite.
Definition
Pseudoloma
Term
is also known as white spot disease for the skin nodules it causes
Definition
Ich
Term
is also known as white spot disease for the skin nodules it causes
Definition
Ich
Term
It is caused by the ciliate protozoa Ichthyophthirius multifilis. It has a similar life cycle to Piscinoodinium; but rather than parasitizing the skin, it infests the epithelium and the gills
Definition
Ich
Term
Fish infected have excessive mucus and white spots on the skin, and they are lethargic
Definition
ich
Term
Diagnosis should be confirmed with microscopic examination of the skin or gills in which the protozoa are visible and should be treated using repeated dilute (1: 5,000) formalin baths until fish are clear of parasites.
Definition
Ich
Term
If the water in the fish tank is supersaturated with excess gas, the fish absorb these dissolved gases through their gills. Supersaturation of air dissolved in the system water can cause
Definition
Gas Bubble Disease
Term
Severe damage is caused as the gases come out of solution, creating bubbles in the bloodstream and throughout the body
Definition
Gas Bubble Disease
Term
Sudden death of large numbers of fish may be the only sign. Fish may show gill hemorrhages; open mouth respiration (gaping); protruding eyes; or small gas bubbles in the cornea of the eyes, surface of the scales, fins, or gills.
Definition
Gas Bubble Disease
Term
Treatment is limited to eliminating the source of supersaturation, which may be caused by air injection at a leaky pipe.
Definition
Gas Bubble Disease
Term
The bacterial populations necessary to detoxify the ammonia waste normally take 4 to 8 weeks to grow large enough to be effective. If a large number of fish are placed into a new system before the bacterial population is established, the ammonia level will quickly rise to toxic amounts, killing large numbers of fish. A similar situation occurs if a low-stocked system suddenly receives an overwhelming number of new fish
Definition
New Tank Syndrome
Term
Prevention involves seeding a new system with a small number of fish before fully stocking the tank, which supplies the necessary bacteria and the ammonia waste to feed the bacteria. The fish population should be gradually increased to the full stocking level over several weeks
Definition
New Tank Syndrome
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