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LaRose Test 2 THYROID FUNCTION TESTS
Clincal Lab diagnosis
30
Health Care
Professional
10/10/2012

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Cards

Term
Increase: Primary hypothyroidism
o Hashimoto’s thyroiditis
o Subacute thyroiditis
o Iodine deficiency Secondary hyperthyroidism
o TSH-secreting pituitary adenoma
Definition
Thyroid Stimulating Hormone (TSH) (2.0-11.0 μU/mL)
Term
Decrease: Primary hyperthyroidism
o Graves’ disease [diffuse toxic goiter]
o Plummer’s disease [multinodular toxic goiter] Secondary hypothyroidism
o Pituitary gland destruction
Definition
Thyroid Stimulating Hormone (TSH) (2.0-11.0 μU/mL)
Term
Increase: Primary hyperthyroidism Secondary hyperthyroidism
Definition
Thyroxine (T4 Total) (0.8-2.8 ng/dL)
Term
Decrease: Primary hypothyroidism Secondary Hypothyroidism due to pituitary insufficiency
Definition
Thyroxine (T4 Total) (0.8-2.8 ng/dL)
Term
Positive: Hashimoto’s thyroiditis Subacute thyroiditis
Definition
Thyroglobulin antibodies (negative)
Term
Increase: Hyperthyroidism Pregnancy Estrogen therapy
Definition
Triiodothyronine (T3) (75-220 ng/dL)
Term
Decrease: Hypothyroidism Iodine insufficiency
Definition
Triiodothyronine (T3) (75-220 ng/dL)
Term
Increased: Cushing’s disease Stress
Addison’s disease
Definition
ACTH [20-100 pg/mL)
Term
Decreased: Cushing’s syndrome Steroid administration
Definition
ACTH [20-100 pg/mL)
Term
Increase: Acute pancreatic disease Cholecystitis Perforated peptic ulcer disease Ectopic pregnancy Alcohol ingestion
Definition
Amylase (0-130 U/L)
Term
Positive in: Multiple Myeloma [found in 75% of patients with multiple myeloma] Waldenström’s macroglobulinemia [malignant plasma cell with excess IgM] Chronic Lymphocytic Leukemia
Definition
Bence Jones protein
Term
Increased: Pregnancy Ectopic pregnancy Hydatidiform mole Choriocarcinoma Some germ cell tumors
Definition
βHCG [<0.8 IU/mL)
Term
Decreased: Threatened abortion Incomplete abortion
Definition
βHCG [<0.8 IU/mL)
Term
Increased: Rheumatoid arthritis Systemic Lupus Erythematosus without renal disease
Definition
CD4 cell count (359-1725 cells/mm3)
Term
Decreased: HIV/AIDS [less than 200 plus a positive Western Blot test] Systemic Lupus Erythematosus with renal disease Herpes infections
Definition
CD4 cell count (359-1725 cells/mm3)
Term
Increased:
Cushing’s disease Cushing’s syndrome Chronic renal failure Starvation Trauma
Definition
Cortisol (4-20 ug/dL)
Term
Decreased: Addison’s disease
Definition
Cortisol (4-20 ug/dL)
Term
Increase: Rheumatoid Arthritis Reiter’s syndrome Crohn’s disease Myocardial infarction Tuberculosis Systemic Lupus Erythematosus
Definition
C-Reactive Protein (6.8-820 μg/dL)
Term
Very high increase: Temporal arteritis Polymyalgia rheumatica
Increase also in the following: Chronic renal failure Malignant disease Severe iron and Vitamin B12 deficiency Autoimmune disorders
Definition
Erythrocyte Sedimentation Rate (Males 1-15; Females 0-20 mm/hr)
Term
Positive: Bleeding peptic ulcer Erosive gastritis Crohn’s disease Ulcerative colitis Diverticulitis Bleeding hemorrhoids GI cancer
Definition
Fecal Occult Blood (negative)
Term
Increase: Hemochromatosis Hemosiderosis Megaloblastic anemia Alcoholic liver disease
Definition
Ferritin (18-300 ng/ml)
Term
Decrease:
Severe protein deficiency Iron deficiency anemia
Definition
Ferritin (18-300 ng/ml)
Term
Positive: Peptic ulcer disease Acute or chronic gastritis Gastric cancer B cell gastric lymphoma
Definition
H. pylori Breath Test (negative)
Term
Increase: Diabetes mellitus Splenectomy
Definition
Hemoglobin A1C (4-6.0%)
Term
Decrease: Hemolytic Anemias Sickle Cell Disease Acute or chronic blood loss
Definition
Hemoglobin A1C (4-6.0%)
Term
Increase: Hemochromatosis Hemosiderosis Hemolysis
Definition
Iron (40-155 ug/dL)
Term
Decrease: Insufficient dietary iron Chronic blood loss from the GI or GU tract
o bleeding peptic ulcer disease
o carcinoma of the colon
o heavy menstruation Late pregnancy
Definition
Iron (40-155 ug/dL)
Term
Increase: Acute pancreatitis Chronic pancreatitis Pancreatic duct obstruction Acute cholecystitis Bowel obstruction
Definition
Lipase (0-160 U/dL)
Term
Positive: Infectious mononucleosis Burkitt’s lymphoma Chronic hepatitis
Definition
Monospot test (negative)
Term
This is a metabolite of norepinephrine and is present in the urine in patients with the following: Pheochromocytoma Neuroblastoma Thyroid medullary carcinoma
Definition
Vanillylmandelic acid (<6.7 mg/day)
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