Shared Flashcard Set

Details

LAI dosing
Long acting injections for Schizophrenia
5
Pharmacology
Professional
11/13/2010

Additional Pharmacology Flashcards

 


 

Cards

Term

Fluphenazine Decanoate

Definition

  • Tmax: 8-24hrs
  • Vehicle: Sesame oil
  • EPS/TD risk: Higher
  •  Starting Dose: 12.5-25mg
  • Target dose: 12.5-50mg
  • Max dose: 100mg/dose
  • PO overlap: Recommended

Term

Haloperidol Decanoate

Definition

  • Tmax: 3-9 days
  • Vehicle: Sesame oil
  • EPD/TD risk: Higher
  • Starting dose: 10-20x PO dose
  • Target dose: 10-15x daily PO dose
  • Max dose: 100mg 1st dose; 400mg/mo
  • PO overlap: Recommended

Term

Risperidone LAI

Definition

 

  • Risperdal Consta
  • Tmax: >3 weeks
  • Vehicle: Microspheres in aqueous sol.
  • EPD/TD: Lower
  • Starting dose: 25mg + PO dose x 3 wks
  • Target dose: 25-50mg
  • Max dose: 50mg
  • PO overlap: required

 

Term

Paliperidone palmitate

Definition

 

  • Invega Sustenna
  • Tmax: 13 days
  • Vehicle: Aqueous sol.
  • EPD/TD risk: Lower
  • Starting dose: 234mg then 156mg 8 days later
  • Target dose: 117mg (39-234mg)
  • Max dose: 234mg
  • PO overlap: not required

 

Term

Olanzapine Pamoate

Definition

  • Zyprexa Relprevv
  • Tmax: ~1 wk
  • Vehicle: aqueous sol.
  • EPD/TD risk: Lower
  • Starting/Target dose: 150-300mg Q2w or 405mg Q4w
  • Max dose: 300mg Q2w or 405mg Q4w
  • PO overlap: Not required

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