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Lab Practical #3
Anatomy and Physiology II Lab
201
Physiology
Undergraduate 3
10/21/2015

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Term
Endocrine System
Definition

 

Collection of glands that produce hormonest hat are secreted to distant target organs in order to maintain the body’s homeostasis 

Term
Hormones
Definition

 

the body’s chemical messengers that transfer information and instructions from one set of cells to another 

Term
Homeostasis
Definition

 

system in which variables are regulated so that internal conditions remain stable and relatively constant 

Term
What do Hormones bind to, to maintain homeostasis and regulate their activity?
Definition
Cell Receptors
Term
Differences in Endocrine Vs. Nervous System
Definition

Endocrine: Slow, long Lasting, Hormone Signaling

Nervous System: Immediate effects, short lasting, electrical signaling 

Term
Thyroid Glands Stimulate:
Definition
  • Thyroxine (T4) or tetraiodothyronine 
  • Triiodothyronine (T3)
  • Calcitonin 
Term
Parathyroid Glands Stimulate:
Definition
Parathyroid hormone (PTH)
Term
Pancrease Stimulates?
Definition

Insulin 

Glycogin 

Term
Pineal Gland stimulate
Definition
Melatonin
Term
Thymus Stimulates?
Definition
Thymosin
Term
The Adrenal Cortex Stimulates?
Definition

Aldosterone 

Cortisol 

Androgens 

Term
Adrenal medulla stimulates?
Definition

Epinephrine 

Norepinephrine (NE)

Term
Ovaries Stimulate?
Definition

Estrogen 

progestrone 

Term
Testes Stimulate?
Definition
Testosterone
Term
Type 1 Diabetes
Definition

 

  • geneticmutation–doesn’t produce functional insulin or insulin receptor 

Term
Type 2 Diabetes
Definition

 

  • obesity induced insulin resistance 

Term
Where is insulin produced?
Definition
  • produced by Beta cells in the pancreas 

Term
what is the overall effect of Insulin?
Definition
to decrease blood glucose
Term
Causes of Type II Diabetes
Definition
  • Insuficiant amount of insulin produced 
  • Insulin resistance (defect in signaling cascade)
Term
Risks of Type II diabetes
Definition
  • weight 
  • lack of exercise 
  • age, race, genetics 
Term
Function of the digestive system
Definition
  • Moves food through alimentary canal where organs can break down food into nutrients that can be absorbed by blood 
  • Ingestion, secretion, mixing/propulsion, digestion,absorption, defecation 
Term
Components of the digestive system
Definition

GI tract

accessory organs 

Term
Mechanical digestion
Definition
  • Mechanical breaking down of food into smaller pieces 
  • small pieces to move through system and also increases surface area 
  • teeth, tounge, esophagus, stomach 
Term
Chemical Digestion
Definition
  • The enzymatic breakdown of large molecules into smaller ones 
  • stomach, small intestine, large intestine, saliva, liver, gallbladder, pancreas 
Term
Peristalsis
Definition

 

  • The wave like muscular contractions of the alimentary canal or other tubular structures by which contents are forced onward. 

Term
Segmentation
Definition

 

  • While peristalsis involves one-way motion in the caudal direction, segmentation contractions move chyme in both directions, which allows greater mixing with the secretions of the intestines. 

Term
What are the layers of the GI tract from the esophagus to large intestine?
Definition

Mucosa

submucosa 

muscularis 

serosa

Term
Mucosa (moist)
Definition

Epithelium, lamina propia, muscularis mucosa (smooth muscle)

Term
Submucosa
Definition

 

Provides nutrients, O2, carries away wastes 

Term
Muscularis
Definition

 

Usually 2 layers, inner circular, outer longitudinal 

Term
Serosa
Definition

Visceral Layer 

Replaced by adventitia in the esophagus 

Term
The teeth serve what purpose?
Definition

 

  •  to break down food into smaller pieces by a mechanical process called mastication

Term
The tongue serves what purpose?
Definition

 

  • mixes food with saliva thus initiating chemical digestion 

Term
Tongue and soft palate both serve what purpose?
Definition

 

  • propel food into the fauces of the oropharynx during swallowing 

Term
Oroparynx recieves food from where?
Definition
the mouth
Term
where does gravity/swallowing move food?
Definition

 

  • from oropharynx into laryngopharynx 

Term
Is the epiglottis closed or open during swallowing so that food can be moved from laryngopharynx into the esophagus?
Definition
Closed
Term
Upper esophageal sphincter
Definition

 

  • controls passage of food from laryngopharynx into esophagus 

Term
Lower esophageal sphincter
Definition

 

  • controls passage of food from esophagus into stomach. 

Term
Pyloric sphincter
Definition

 

  1. controls passage of food from stomach to small intestine 

Term
Functions of the stomach
Definition
  • secreation of gastric juices, mixing and propulsion 
  • Gatric juices begin digestion of protien and lipids 
Term
Parietal Cell
Definition
Secretes hydrochloric acid and intrinsic factor
Term
Chief cell
Definition
secretes pepsinogin and gastric lipase
Term
G Cell
Definition
secretes the hormone gastrin
Term
Pancreatic and Intestial enzymes digest what?
Definition

 

larger food molecules of CHOs, proteins, and lipids into smaller absorbable molecules 

Term
Illeocecal sphincter
Definition

 

controls movement of food from ileum into large intestine 

Term
Large Intestine
Definition
  • also called the colon 
  • main job is to absorb water, thus concentrating feces, and secrete waste 
  • bacteria complete the digestion 
Term
Parietal peritoneum
Definition

 

  • Lines the inner surface of the

    abdominopelvic wall 

Term
Visceral peritoneum
Definition

 

  1. Covers organs within the abdominopelvic cavity 

Term
what key part to the peritoneum is found in other serous membranes and secure organs together and to the abdominal walls?
Definition
Large Folds
Term
Retroperitoneal Organs
Definition
Kidneys and pancreas
Term
Salvary glands
Definition

located in mouth and tongue. 

 

  • Secrete saliva that begins chemical digestion 

 
Term
Tongue
Definition

 

  • maneuvers food in mouth 

Term
Teeth
Definition
mechanically break down food
Term
Pancreas
Definition

 

  •  secretes digestive enzymes into duodenum via pancreatic duct 

Term
Liver
Definition

 

  • produces bile (emulsifies fats) 

Term
Gallbladder
Definition

 

  • stores and concentrates bile. Dumps bile into duodenum via common bile duct 

Term
Emulsify
Definition

 

The process of breaking fats into smaller pieces 

Term
Hepatic Triad
Definition
  • Artery
  • Vein 
  • Bile Duct 
Term
What gland influences metabolism, growth and development, and body temperature?
Definition
Thyroid
Term
What gland is primarily involved in brain development in children?
Definition
Thyroid
Term
What are the main thyroid hormones?
Definition

T3 (Stronger)

T(more common)

Term
What controls the Thymus?
Definition

 

  • Controlled by the pituitary gland and hypothalamus 

Term
What is released when thyroid levels decrease?
Definition

 

  • hypothalamus releases TSH Releasing Hormone (TRH) 

Term
TRH alerts what?
Definition

 

  •  the pituitary gland to produce thyroid stimulating hormone (TSH) 

Term
What is the main function of enzyme?
Definition
to speed up chemical reactions
Term
Anabolize
Definition
Build
Term
Catabolize
Definition
Breaks down
Term
Enzymes require what to optimally function?
Definition
a certain pH and temperature
Term
What pH does the mouth have?
Definition
neutral
Term
What pH does the small intestine have?
Definition
Neutral
Term
What pH does the stomach have?
Definition
Very acidic
Term
Sites of secreation
Definition

Salivary glands

stomach 

pancreas

small intestine 

Term
Sites of action
Definition

mouth 

stomach 

small intestine 

Term
What is the Substrate for Salivary amylase
Definition
Starches
Term
What is the substrate for Pancreatic amylase?
Definition
Starches
Term
what is the substrate alpha-dextrinase?
Definition
alpha-dextrins
Term
what is the substrate for sucrase?
Definition
Sucrose
Term
what is the substrate for lactase?
Definition
Lactose
Term
what is the substrate Maltase?
Definition
Maltose
Term
What is the substrate for Pepsin
Definition
Protein
Term
what is the substrate for Trypsin/Chymotrypsin?
Definition
Protein
Term
what is the substrate for aminopeptidase?
Definition
Protien
Term
What is the substrate for dipeptidase?
Definition
Dipeptides
Term
What is the substrate for Lingual Lipase
Definition
Triglycerides
Term
What is the substrate for Gastric Lipase?
Definition
Triglycerides
Term
What is the substrate for Pancreatic Lipase
Definition
Triglycerides
Term
What is the product of Salivary amylase?
Definition
Smaller polysaccharides
Term
What is the product of pancreatic amylase?
Definition
disaccharides
Term
what is the product of alpha-dextrinase?
Definition
monosaccharides
Term
What is the product of sucrase?
Definition
monocaccharides
Term
what is the product of lactase?
Definition
monosacchairdes
Term
what is the product of maltase?
Definition
monosacchairdes
Term
Where is the location of reaction of salivary amylase?
Definition
Mouth
Term
where is the location of reaction of pancreatic amylase?
Definition
Small Intestine
Term
what is the location of reaction for alpha-dextrinase?
Definition
Small instestine
Term
what is the location of reaction for sucrase?
Definition
Small intestine
Term
What is the location of reaction for Lactase?
Definition
Small instestine
Term
where is the location of reaction for Maltase?
Definition
Small Intestines
Term
Location of reaction for pepsin
Definition
Stomach
Term
location of reaction for Trypsin/chymotrypsin
Definition
small intestine
Term
location of reaction for Aminopeptidase
Definition
small intestine
Term
Location of reaction for dipeptidase
Definition
small intestine
Term
Site of secreation for salivary amylase?
Definition
Salvary glands
Term
Site of secreation for pancreatic amylase
Definition
Pancreas
Term
site of secreation for alpha-dextrinase
Definition
Brush Border (SI)
Term
site of secreation for sucrase
Definition
Brush Border (SI)
Term
site of secreation for lactase
Definition
Brush Border (SI)
Term
site of secreation for maltase
Definition
Brush Border (SI)
Term
Product of lingual lipase
Definition
free fatty acids and glycerol
Term
product of gastric lipase
Definition
free fatty acids and glycerol
Term
product of pancreatic lipase
Definition
free fatty acids and glycerol
Term
location of reaction for lingual lipase
Definition
Stomach
Term
location of reaction for gastric lipase
Definition
stomach
Term
location of reaction for pancreatic lipase
Definition
small intestine
Term
Site of secreation for pepsin
Definition
chief cells
Term
site of secreation for trypsin/chymotrypsin
Definition
pancreas
Term
List 5 major endocrine glands
Definition

 

  •   Pineal Gland

  • Hypothalamus

  • Pituitary gland

  • Thyroid Gland

  • Parathyroid Gland

  • Thymus

  • Adrenal Glands

  • Ovaries

  •  Testes 

Term
List two differences between the endocrine and nervous systems
Definition

Endocrine: Slow, long lasting, hormone signaling 

Nervous: Immediate effects, short lasting, electrical signaling 

Term
what structure connects the hypothalamus to the pituitary gland?
Definition
Infundibulum
Term
What 3 things does the Adrenal cortex stimulte?
Definition

Aldosterone

Cortisol

Androgens 

Term
What is the function of calcitonin from the thyroid gland?
Definition
Calcitonin lowers serum calcium levels by inhibition of bone reabsorbing osteoclasts
Term
Where is the function of oxytocin and where is it secreated from?
Definition

Posterior Pituitarty gland 

Stimulates uterine contraction and breast contraction for milk release 

Term
What horomone is responsible for basal metabolic rate and where is it secreated?
Definition

Throxin 

Secreated from thyroid gland 

Term
If you were to eat four sugar doughnuts and a large pepsi, which hormone would you expect to be secreated at higher levels?
Definition
Insulin
Term
This controls how quickly the doby uses energy, makes proteins, and controls how sensitive the body should be to other hormomes
Definition
Thyroid
Term
What would be the result of a thyroidectomy?
Definition
Increased TSH secreation
Term
The __________ are chisel-like cutting teeth used to bite off a piece of food
Definition
Incisors
Term

 

What is the name of the membrane that extends from the stomach to the liver, covers the small intestine like an apron, and is an excellent storage site for fat? 

Definition
Greater omentum
Term

 

The wavelike muscular contractions of the alimentary canal or other tubular structures by which contents are forced onward is called _______. 

Definition
Peristalis
Term
List the tissue layers in the esophagus
Definition

mucosa

submucosa 

muscularis 

adventitia (serosa when not in the esophagus)

Term
What is the function of rugae in the stomach?
Definition

 

The function of the rugae is to allow the stomach and other %ssue to expand as needed to assist in the digestion of food. 

Term
List the principle sites of enzyme secreation and enzyme action
Definition
  • Sites of Secreation

Salivary Glands

Stomach

Pancreas

Small Intestine

  • Sites of Action 

Mouth

Stomach

Small intestine  

Term
Where are Bile salts made?
Definition
Liver
Term
Where do Bile Salts work?
Definition
Small Intestine
Term
What is the substrate for Bile salts?
Definition
Fat
Term
What are the products of Bile salts?
Definition
Fat droplets
Term
Wher is amylase made?
Definition
Salivary Glands
Term
Where does amylase work?
Definition
Mouth
Term
What is the substrate for Amylase?
Definition
Starch
Term
What are the products of Amylase?
Definition
Maltose
Term
Where is protease made?
Definition
Stomach Cells
Term
Where does proetease work?
Definition
Stomach
Term
What is the substrate for protease?
Definition
Protein
Term
What are the products of protease
Definition
Amino Acids
Term

 

Pretend you just ate a cookie, make a flow chart of all the structures the cookie passes through. Include sphincters and regions of each organ 

Definition

 

Mouth àOropharynx àLaryngopharynx àUpper Esophageal SphincteràEsophagusàLower Esophageal SphincteràStomach (CardiaàFundus àBodyàPyloris)àPyloric SphincteràSmall Intestine (DuodenumJejumumàIleum)àIleocecal SphincteràLarge Intestine (CecumàAscending ColonàTransverse ColonàDescending ColonàSigmoid Colon)àRectumàAnal CanalàInternal and External Anal SphincteràAnus 

Term

What type of tissue is found in the esophagus?

 
Definition
Stratified squamous epithelium
Term

 

The small intestine is the only structure to have TWO distinguishing characteristics (versus the stomach and large intestine). What are they? 

Definition

 

Only the small intestine has both villi and crypts. Stomach and large intestine only have crypts. 

Term
What hormones are secreteded by the Anterior pituitary gland?
Definition
  1. HGH -Human gorwth hormone 
  2. TSH- thyroid-stimulating hormone 
  3. FSH- follicle-stimulating hormone 
  4. LH- Luteinizing hormone 
  5. Prolactin
  6. ACH - adrenocorticotropic hormone 
  7. MSH- melanocyte stimulting horomne 
Term
what hormones are secreated by the posterior pituitary gland?
Definition
  1. ADH -Anti-diuretic hormonne 
  2. oxytocin 
Term
What hormones are secreated by the thyroid gland?
Definition
  1. Thyroxine 
  2. Triiodothyronine 
  3. calcitonin 
Term
What hormone is secreated by the parathyroid glands?
Definition
Parathyroid hormone
Term
What hormones are secreated by the adrenal cortex?
Definition
  1. Aldosterone 
  2. cortisol
  3. androgens 
Term
what hormones are secreated by the adrenal medulla?
Definition
  1. epinephrine
  2. noepinephrine 
Term
What hormones are secreated by the pancreas?
Definition
  1. Insulin
  2. Glucagon 
Term
what hormones are secreated by the ovaries?
Definition
  1. estrogen 
  2. progesterone 
Term
what hormones are secreated by the testes?
Definition
testosterone
Term
What hormones are secreated by the pineal gland?
Definition
meletonin
Term
what hormones are secreated by the thymus?
Definition
thymosin
Term
location of the Target cells for the human growth hormone?
Definition
Cartiage, bone, skeletal muscle, liver, and other body tissues
Term
location of the Target cells for Thyroid stimulating hormone
Definition
Thyroid gland
Term
location of target cells for the follicle stimulating hormone
Definition
Testes and ovaries
Term
location of target cells for the luteinizing hormone
Definition
testes and ovaries
Term
location of target cells for prolactin
Definition
mammary gland
Term
location of target cells for the adrenocorticotropic hormone
Definition
Adrenal Cortex
Term
location of target cells for the melanocyte stimulating hormone
Definition
Skin
Term
location of target cells for the Anti-diuretic hormone
Definition
Kidneys
Term
Location of target cells for the oxytocin hormone
Definition
Uterus and mammary glands
Term
Location of target cells for Thyroxine and Triiodothyronine?
Definition
Most body cells
Term
location of target cells for calcitonin?
Definition
osteoclast cells in bones
Term
location of target cells for the parathyroid hormone?
Definition
osteoclast cells in bones
Term
location of target cells for aldosterone
Definition
Kidneys
Term
Location of target cells for cortisol
Definition
Liver, muscle, and cells involved in body defense
Term
Location of target cells for androgens
Definition
uterus, mammary glands, and other body cells involved in secondary sex characteristic?
Term
Location of target cells for epinephrine and norepinephrine?
Definition
Body cells involved in fight-or-flight response
Term
loaction of target cells for insulin
Definition
Most body cells
Term
Location of target cells for estrogen and progestrone
Definition
Uterus, mammary glands, and other body cells involved in female sexual characterisitcs
Term
location of target cells for meletonin
Definition
Brain
Term
location of target cells for thymosin
Definition
T cells (type of white blood cell involved in immunse response)
Term
Function of Epinephrine and Norepinephrine
Definition
Promotes fight or flight response
Term
Function of Insulin
Definition
Decreases blood glucose levels by transporting glucose into body cells
Term
Function of glucogen
Definition
increases blood glucose levels by stimulating liver to break down glycogen into glucose
Term
What do estrogen and progestrone stimulate?
Definition
stimulates developemnt of female sex characteristics; helps regulate mestrual cycle
Term
what does testosterone stimulate?
Definition
Stimulates development of male sex characteristics; stimulates male sex drive; regulates sperm production
Term
Function of meletonin
Definition
Helps to set biological clock
Term
Function of Thymosin
Definition
Promotes maturation of t cells for the immune response
Term
What does HGH stimulate?
Definition
Stimulates secreation of hormones that stimulate body growth and metabolism
Term
What does TSH stimulate?
Definition
Stimulates growth of thyroid gland and secreation of its hormones
Term
what does FSH stimulate?
Definition
Stimulaties sperm production. Stimulates oocyte production and estrogen secreation
Term
What does LH stimulate?
Definition
Stimulates secreation of testosterone. triggers ovulation and stimulates secreation of estrogen and progestrone
Term
What does prolactin stimulate?
Definition
Stimulates production and secreation of milk
Term
What does the adrenocorticotropic hormone stimulate?
Definition
Stimulates secreation of hormones by adrenal cortex
Term
The melanocyte-stimulating hormone stimulates
Definition
Darkining of the skin pigmnents
Term
Function of ADH
Definition
Decreases water lost in urine by returning water to the blood
Term
Function of oxytocin
Definition
Stimulates uterine contractions and milk ejection during suckling
Term
Function of thyroxine and triiodothyonine
Definition
Increases BMR
Term
Function of calcitonin
Definition
Decreaes blood calcium levels by inhibitting osteoclasts
Term
function of parathyroid hormone
Definition
increase blood calcium levels by stimuating osteoclasts to break down bone matrix
Term
Function of aldosterone
Definition
decreases sodium and water loss in urine by returning sodium and water to the blood
Term
function of cortisol
Definition
increases resistance to stress, increases blood glucose levels and decreaes inflamation
Term
Function of androgens
Definition
insignificant in males, increases sex drive in females.
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