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Lab Med T3 - Endocrin I
pa school
31
Health Care
Graduate
07/27/2010

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Cards

Term
3 hypothalmic disorders
Definition
1. secondary hypopituitarism
2. centtral Diabetes insipidus
3. growth disorders from lack of GHRH
Term
most common pituitary tumor
Definition
prolactinoma
Term
lab findings in prolactinoma
Definition
elevated prolactin and decreased FSH/LH
Term
IGF-1
Definition
insulin like growth factor from GH release; stimulates bone growth
Term
lab test for decreased gonadotropins
Definition
GnRH stimulation test; hypopituitarism yields no increase in FSH/LH... eventual increase in FSH/LH in hypothalmic disorder
Term
lab test for low levels of GH
Definition
arginine-insulin stimulation test
Term
how does secondary hypocortisolism affect ADH
Definition
increased ADH levels due to loss of inhibitory effects of cortisol on ADH
Term
metyrapone test
Definition
stimulation test of the pituitary ACTH
Term
test distinguishes btwn central and nephrogenic diabetes insipidus
Definition
water depravation test; injection of ADH and look at OSM of urine (increase in uosm = central DI)
Term
increase/decrease in TBG changes the ____ but not the ___
Definition
changes the total T4 levels but not the Free T4
Term
best overall screening test for thyroid function
Definition
TSH
Term
thyroglobulin
Definition
marker for thyroid cancer
Term
radioactive iodine 131 uptake: hypo vs. hyper thyroid
Definition
hypoactive = decreased uptake
hyperactive - increased uptake
Term
iodine uptake of pt w initial phase of thyroiditis
Definition
decreased uptake due to inflammation
Term
131 uptake of pt taking xs hormone
Definition
decreased uptake
Term
part of the adrenal cortex that releases glucocorticoids
Definition
zona fasciculata
Term
part of the adrenal cortex that releases mineralocorticoids
Definition
zona glomerulosa
Term
part of the adrenal cortex responsible for the release of sex hormones
Definition
zona reticularis
Term
ectopic cushings dz:
Definition
usually small cell carcinoma
Term
excelenct screening test for cushings
Definition
urine free cortisol
Term
which cushings is suppressed by the high dose dexamethasone supression test?
Definition
pituitary
Term
which cushings has increased ACTH
Definition
pituitary and ectopic
Term
24hr urine for VMA & metanepherines
Definition
pheochromocytoma
Term
CBC in pheochromocytosis reveals
Definition
neutrophilic leukocytosis; due to inhibition of neutrophil adhesion molecules
Term
most common cause of acute adrenal insufficiency
Definition
rapid withdrawal of corticosteroids
Term
most common cause of chronic adrenal insufficiency
Definition
autoimmune (addisons)
Term
serum glucose is __% higher than Whole blood glucose
Definition
15%
Term
criteria for DM dx
Definition
2 fasting glu >126
2hr GTT >200
Term
when does gestational screening occur for gestation diabetes
Definition
24-28wks
Term
what is a positive level for the 1hr GTT in gestational screening
Definition
>140
Term
define positive screen for 3hr GTT
Definition
if 2 or more of the values are above criteria: Fasting>95, 1hr>180, 2hr>155, 3hr>140
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