Term
|
Definition
|
|
Term
| 1st Generation Adrenergic Antagonists |
|
Definition
| Propranolol, Pindolol, Nadolol |
|
|
Term
| 2nd Generation Adrenergic Antagonists |
|
Definition
| Atenolol, Metoprolol, Esmolol |
|
|
Term
| 3rd Generation Adrenergic Antagonists |
|
Definition
|
|
Term
| Labetalol and Carvedilol targets |
|
Definition
| This drug targets Alpha-1, Beta-1, Beta 2 receptors |
|
|
Term
| Propranolol, Pindolol, Nadolol targets |
|
Definition
| This drug targets Beta-1, Beta-2 receptors |
|
|
Term
| Atenolol, Metoprolol, Esmolol targets |
|
Definition
| This drug targets Beta-1 receptors |
|
|
Term
| Phentolamine and Phenoxybenzamine targets |
|
Definition
| This drug targets Alpha-1, Alpha-2 receptors |
|
|
Term
| Terazosin and Tamsulosin targets |
|
Definition
| This drug targets Alpha-1 receptors |
|
|
Term
|
Definition
| This drug targets Alpha-2 receptors |
|
|
Term
| Alpha-blockers for treating Hypertension |
|
Definition
| Terazosin is helpful in treating |
|
|
Term
|
Definition
| This drug blocks alpha-1 adrenoceptors on vascular smooth muscle, and inhibits sympathetic nerve mediated vasoconstriction |
|
|
Term
| Drug for treating Benign prostatic hyperplasia |
|
Definition
| Tamsulosin is helpful in treating |
|
|
Term
| Drug for treating Peripheral Vascular Disease |
|
Definition
| Phentolamine is helpful in treating (1) |
|
|
Term
| Drug for treating Raynaud's Disease and Frosbite |
|
Definition
| Phentolamine is helpful in treating (2) |
|
|
Term
| Drug for treating Impotence |
|
Definition
| Phentolamine and Yohimbine is helpful in treating |
|
|
Term
| Cardiovascular adverse effects of alpha-blockers |
|
Definition
| Orthostatic hypotension (first dose), reflex tachycardia, palpitations, fluid retention, weight gain, peripheral edema is an adverse effect of these |
|
|
Term
| CNS adverse effects of alpha-blockers |
|
Definition
| Dizziness, drowsiness, fatigue, headache is an adverse effect of these |
|
|
Term
| GI adverse effects of alpha-blockers |
|
Definition
| Abdominal pain, constipation/diarrhea, nausea is an adverse effect of these |
|
|
Term
| Beta-blocker for treating Hypertension |
|
Definition
| Labetalol, Propranolol, Atenolol is helpful in treating |
|
|
Term
| Beta-blocker antihypertensive mechanisms |
|
Definition
| Decreased CO, decreased renin-angiotensin release, possibly CNS effects |
|
|
Term
| Drug for treating Angina Pectoris |
|
Definition
| Metoprolol is helpful in treating (1) |
|
|
Term
| Drug for treating arrhythmias |
|
Definition
| Propranolol is helpful in treating (1) |
|
|
Term
| Drug for Congestive Heart Failure |
|
Definition
| Carvedilol is helpful in treating |
|
|
Term
| Beta-blocker mechanism to protect heart during CHF |
|
Definition
| These blockers take away the sympathetic drive on the heart which would hasten the heart failure |
|
|
Term
| Drug for recurrent myocardial infarction |
|
Definition
| Metoprolol is helpful in treating (2) |
|
|
Term
| Drug for treating glaucoma |
|
Definition
| Propranolol is helpful in treating by reducing aqueous humor formation |
|
|
Term
| Drug for treating muscle tremor |
|
Definition
| Propranolol is helpful in treating (3) |
|
|
Term
| Drug for treating migrain headache |
|
Definition
| Propranolol is helpful in treating (4) |
|
|
Term
| Cardiac adverse effects of beta-blockers |
|
Definition
| Bradycardia, AV nodal block, decreased cardiac work is an adverse effect of these |
|
|
Term
| CNS adverse effects of beta-blockers |
|
Definition
| Lethargy, depression, fatigue, altered sleep is an adverse effect of these |
|
|
Term
| Respiratory adverse effects of beta-blockers |
|
Definition
| Wheezing and bronchoconstrition in asthma is an adverse effect of these |
|
|
Term
| Reboud/withdrawal adverse effects of beta-blockers |
|
Definition
| Cardiac ischemia, and increased BP is an adverse effect of these |
|
|
Term
| Clonidine, Guanfacine, guanabenz MOA |
|
Definition
| This stimulates alpha-2 adrenoceptors in CNS activating inhibitory nerves, decreasing sympathetic nerve outflow from the CNS |
|
|
Term
|
Definition
| This blocks the vesicular transporter, inbhits uptake of dopamine and NE into storage vesicles, depletes NE from nerves |
|
|
Term
| Adrenergic neuron blockers for treating hypertension |
|
Definition
| Clonidine, guanabenze (secondary), Reserpine (last-resort) are helpful in treating |
|
|
Term
| Adrenergic neuron blockers for treating ADHD, autism, Tourettes, EtOH/nicotine/opiate withdrawal, pain |
|
Definition
| Clonidine, guanfacine are helpful in treating these CNS disorders |
|
|
Term
| Adverse effects of clonidine, guanfacine, guanabenze |
|
Definition
| Sedation, fatigue, altered sleep, impaired ejaculation, dry mouth is an adverse effect of these drugs |
|
|
Term
| Adverse effects reserpine |
|
Definition
| Diarrhea, postural hypotension, Na+ retention, sedation, nightmares, depression, suicide is an adverse effect of these drugs |
|
|
