Term
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Definition
| Gas Exchange, Perfusion, Airway |
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Term
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Definition
Anti-inflammatory
Antipyretic
Analgesic
-Used to treat mild to moderate pain, fever, and numerous inflammatory conditions
-Reye syndrome
Popular because it has all 4 A's! |
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Term
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Definition
3A's: Anti-inflammatory, antipyretic, analgesic
Widely available OTC (leads to overuse)
Produce strong effects without adverse effects associated with steriods |
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Term
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Definition
2A's: Analgesic, Antipyretic
Used to treat mild to moderate pain
USed in place of NSAIDS or salicylates
Most frequently used drugs for managing pain and fever in children
OTC
Can be extremely toxic
Extremely high doses can be toxic to the liver which can lead to death |
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Term
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Definition
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Term
Salicylates
Aspirin
Indication for use |
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Definition
| for the treatment of mild to moderate pain, fever, and numerous inflammatory conditions including rheumatoid arthritis and osteoarthritis. |
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Term
Salicylates
Aspirin
Adverse Effects |
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Definition
GI distress (nausea, dyspepsia, heartburn, epigastric discomfort) auditory toxicity (tinnitus), & bleeding (blood loss, abnormalities)
Salicylism (high levels) dizziness, ringing in the ears, difficulty hearing |
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Term
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Definition
Allergy, Renal Disease, bleeding disorders, chieckpox of flu,
Baseline
Skin
Temp
CNS
Pulse, blood pressure, and perfusion
Evaluate respirations and adventitious sounds
Perform a liver evaluation
Monitor Lab (CBC, Liver function, urinalyss, stool, clotting) |
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Term
Salicylates
Implementation |
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Definition
Administer with food
Administer drug (toxic levels)
monitor for severe reaction (gastric lavage, inducing vomit, admin charcoal)
Ensure hydration
provide teaching |
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Term
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Definition
Monitor patient response to the drug (improvement, relief of signs and symptoms of inflam)
Monitor AE
Evaluate effectiveness of teaching plan
Monitor effectiveness of comfort measures and compliance with the drug regimen |
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Term
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Definition
| -Ibuprofen, Acetaminophen |
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Term
NSAIDS
Ibuprofen
Indications for use |
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Definition
| Most NSAIDS block inflammation before all of the signs and symptoms can develop. NSAIDS also block various other functions of the prostaglandins, including protection of the stomach lining, regualtion of blood clotting and water and salt balance in the kidney. |
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Term
NSAIDS
Ibuprofen
Adverse Effects |
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Definition
common adverse reactions: GI distress(constipation, diarrhea, flatulence), CNS effects, bleeding (platelet inhibition),& hepatotoxicity
headache, dizziness, somnolence, and fatigue (related to prostglandin activity in the CNS)Bone Marrow Depression with chronic use |
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Term
| -Know NSAID drug to drug interactions |
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Definition
| : decrease effects of beta blockers, decrease diuretic effect (Loop diuretics), & lithium toxicity |
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Term
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Definition
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Term
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Definition
| Used to treat moderate to mild pain and fever and often is used in place of the NSAIDS or salicylates. Most frequently used drug for managing pain and fever in children.Can be extremely toxic. |
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Term
Acetaminophen
Tylenol
Indication |
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Definition
| For the treatment of pain and fever associated with a variety of conditions, including influenza, for the prophylaxis of children receiving diphtheria-pertussis-tatanus immunizations; and for the relief of musculoskeletal pain associated with arthritis |
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Term
Acetaminophen
Tylenol
Adverse effects |
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Definition
headache, hemolyic anemia, renal dysfunction, skin rash, and fever.
Hepatoxicity |
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Term
Acetaminophen
Tylenol
Drug to drug |
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Definition
| increased risk for bleeding with oral anticoagulants because of effects on liver; toxicity with chronic ethanol ingestion; hepatotoxicity with barbiturates |
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Term
Acetaminophen
Tylenol
Assess |
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Definition
Allergies, cardiovascular dysfunction, hypertension, and gastrointestinal bleeding or peptic ulcer
-Baseline
-blood pressure, perfusion, pulse resperations, adventitious sounds, liver, bowel, CBC |
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Term
| Know medication used in treatment of acetaminophen overdose |
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Definition
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Term
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Definition
| used for treating arthritis and aggressively affect the process of inflammation. Many rheumatollogists are selecting DMARDS early in diagnosis, before damage to the joints has occured, because it can alter the course of the arthritis. |
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Term
DMARDS
Indications for use |
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Definition
Agressive anti-inflammatory
Used in patients who have not responded to other traditional therapies |
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Term
DMARDS
Know common adverse effects: |
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Definition
local injection site reactions, pain with injection, increased risk of infection. Hepatic toxicity and rashes. Bone marrow depression
Allergic reaction
CNS problems |
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Term
| Know the nursing for patients taking these medications: |
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Definition
| similar to nursing for patients taking NSAID’s and related agents |
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Term
DMARDS
. Lifespan considerations: |
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Definition
Children are more susceptible to the GI and CNS effects of drugs.
Aspirin and choline magnesium trisalicylate are the only salicylates recommended for children.
Adults need to be caution about overdoes and toxic affects (Due to OTC)
Older adults-moer susceptible to CNS and GI effects of these drugs. Dose adjustment is not needed for many of these agents. |
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Term
| Celebrex (Cox-2 Inhibitor) |
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Definition
Cox 2 is an enzyme that's activated in response to trauma and injury. Decreases pain, inflammation
Prevents protective vasodilation, allows platelet clumping (Which could lead to myocardial infarction and cerebreovascular accident)
Myriad of skin reactions, including Steven Johnson syndrome |
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