| Term 
 
        | What are the classifications of HTN? |  | Definition 
 
        | - Normal - under 120/80 - Pre-HTN - Systolic 120-139 and Diastolic 80 - 89
 - HTN stage 1 - Systolic 140-159 and diastolic 90-99
 HTN stage 2 - Systolic over 160 and Diastolic over 100
 |  | 
        |  | 
        
        | Term 
 
        | How does and increase in BP increase CVD risk? |  | Definition 
 
        | For ages 40-70, every 20 mmHG systolic increase and 10 mmHg diastolic increase doubles CVD risk |  | 
        |  | 
        
        | Term 
 
        | Why is ambulatory BP monitoring used? |  | Definition 
 
        | To measure white coat HTN, assess drug resistance, hypotension, and other dysfunction |  | 
        |  | 
        
        | Term 
 
        | What are major CV risk factors? |  | Definition 
 
        | HTN Cigarette smoking
 Obesity (BMI >/ 30)
 Physically inactive (desk job)
 Dyslipidemia of DMII
 Microalbumin or GFR < 60
 Age over 55 in men or 65 in women
 Family history of CVD (under 55 in men or 65 in women)
 |  | 
        |  | 
        
        | Term 
 
        | What are the areas of target organ damage? |  | Definition 
 
        | - Heart - LV hypertrophy, angina, CHF - Brain - stroke or TIA
 - Chronic Kidney Disease
 - Peripheral Artieries
 - Retinopathy
 |  | 
        |  | 
        
        | Term 
 
        | What are causes of secondary HTN? |  | Definition 
 
        | - Sleep apnea due to obesity or metabolic syndrome - Drug induced
 - Chronic Kidney disease - RAAS malfunctions
 - Primary Aldosteronism
 - Steroid therapy/Cushing syndrome
 - Renovascular disease
 |  | 
        |  | 
        
        | Term 
 
        | What lifestyle modifications lower BP? |  | Definition 
 
        | Weight reduction DASH diet
 Sodium reduction - 2400 mg/day
 Increased physical activity to 30 min/day at least 3x/week
 moderation of alcohol to 1-2 drinks/day
 |  | 
        |  | 
        
        | Term 
 
        | What is the goal BP for people with hypertension? |  | Definition 
 
        | LESS than 140/90 or 130/80 with diabetes/CKD |  | 
        |  | 
        
        | Term 
 
        | What is the basis of HTN therapy? |  | Definition 
 
        | Thiazide-type diuretics. Use as initial therapy unless there is a compelling indication |  | 
        |  | 
        
        | Term 
 
        | What is the only class of medication not appropriate for Heart Failure? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Which drugs are recommended for initial treatment of post-MI? |  | Definition 
 
        | Beta-blockers, AceI, and aldosterone antagonists |  | 
        |  | 
        
        | Term 
 
        | Which 2 drugs are not appropriate for initial treatment of high coronary disease risk? |  | Definition 
 
        | ARBs and Aldosterone antagonists |  | 
        |  | 
        
        | Term 
 
        | What is the only class of medication not appropriate for initial treatment of diabetes? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Which two drugs can be used for initial treatment of CKD? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Which two drugs can be used for initial treatment of stroke prevention? |  | Definition 
 
        | A diuretic(thiazide) and AceI |  | 
        |  | 
        
        | Term 
 
        | What is the difference between hypertensive urgency and emergency? |  | Definition 
 
        | Presence of target organ damage in emergency |  | 
        |  |