Term
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Definition
- Meds for Peptic Ulcer Disease
- Laxatives
- Anti-diarrheals
- Anti-emetics
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Term
|
Definition
- hypersecertion of acid and pepsin damages, mucosa, dec bicarb
- abnormality in mucosa-> inc permeability of mucosa to H+ -> histamine release -> inc acid
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Term
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Definition
- confirmed infection with H. pylori
- 2-3 Abx used, 10-14 days
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Term
| Histamine 2 Receptor Blockers |
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Definition
- Promotes ulcer healing by suppressing secretion of acid
- Types:
- cimetidine/Tagamet
- ranitidine/ Zantac
- famotidine/Pepcid
- nizatidine/Axid
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Term
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Definition
- MOA: blocks H2 receptors on parietal cells-> suppresses secretion of acid, dec H+
- IND: tx gastric and duodenal ulcers, prophylaxis of ulcers, GERD (heartburn), Zollinger-Ellison syndrome, prevent aspiration pneumonitis
- AE: antiandrogenic, GI
- DI: warfarin, dilantin,theophylline, antacids
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Term
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Definition
- promote ulcer healing by suppressing acid secretion
- Types: omeprazole/Prilosec, esomeprazole/Nexium, pantoprazole/Protonix, lansoprazole/ Prevacid, raberazole/Aciphex
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Term
|
Definition
- MOA:suppresses acid secretion by inhibiting enzyme that generates acid
- IND: PUD, GERD, hypersecretory conditions
- AE: GI, inc.risk of gastric acid CA
- DI:atazanavir, itraconazole
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