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Introduction
Mechanisms of action
33
Pharmacology
Graduate
08/13/2012

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Term
cell wall synthesis inhibitor
Definition
amoxicillin, amoxicillin with clavulanate, and cephalexin
Term
binds 50S ribosomal subunit
Definition
azithromycin and erythromycin
Term
interferes with DNA gyrase
Definition
coprofloxacin, and levofloxacin
Term
antimetabolite
Definition
trimethoprim/sulfamethoxazole
Term
calcium channel antagonist
Definition
amlodipine, diltiazem, nifedipine, and verapamil
Term
HMGCoA reductase inhibitor
Definition
atorvastatin and simvastatin
Term
ACE inhibitor
Definition
Fosinopril and lisinopril
Term
angiotensin receptor blocker
Definition
candesartan, and losartan (II)
Term
adrenergic antagonist
Definition
metaprolol (Beta 1), propanolol (Beta 1 and 2), and terazosin (alpha)
Term
block Na reabsorption
Definition
Furosemide (TAL) and hydrochlorothiazide (EDT)
Term
block platelets
Definition
aspirin (COX and inhibits prostaglandin synthase) and clopidogrel (binds ADP-dependent receptor on platelets)
Term
Vitamin K antagonist
Definition
warfarin
Term
binds endogenous insulin receptor
Definition
insulin rapid/short acting and insulin, intermed/long acting
Term
increases insulin secretion
Definition
glyburide
Term
decreases heptic glucose and increases insulin sensitivity
Definition
metformin
Term
improves insulin action in presense of insulin
Definition
rosiglitazone
Term
DPP-4 inhibitor
Definition
sitagliptin
Term
H/K ATPase inhibitor; blocks gastric acid secretion
Definition
Esomeprazole and omeprazole
Term
Histamine-2 receptor blocker, reduce gastric acidity
Definition
famotidine and ranitidine
Term
Beta 2 agonist
Definition
albuterol and slmeterol
Term
inhibits phospholipase A2
Definition
fluticasone and prednisone
Term
nonsedating anthistamine
Definition
cetirizine
Term
cholinergic antagonist
Definition
ipratropium
Term
leukotriene antagonist
Definition
montelukast
Term
serotonin-norepinephrine reuptake inhibitor (SNRI)
Definition
dsevenlafaxine and duloxetine
Term
benzodiazepine receptor agonist
Definition
diazepam and lorazepam
Term
selective serotonin reuptake inhibitor (SSRI)
Definition
excitalopram, paroxetine and sertraline
Term
Na chnnel blocker
Definition
phenytoin and topiramate
Term
NE and dopamine reuptake inhibitor
Definition
bupropion
Term
Glutamate receptor blocker
Definition
topiramate
Term
opiate agonist
Definition
morphine, oxycodone and oxycodone sustained release
Term
inhibits COX, inhibits prostaglandin release
Definition
ibuprofen and naproxen
Term
Selective COX-2 inhibitor, inhibits prostaglandin production
Definition
celecoxib
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