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| study of biological functions of the body |
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| cell --> tissue --> organ --> system |
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-1813-1878 -French man that discovered the milieu intérieur (inside wall of your body) |
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| the inside wall of your body |
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| discovered the milieu intérieur (inside wall of your body) |
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| one of the core concepts of physiology |
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-1871-1945) -developed the term homeostasis and studied some mechanisms of it |
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| developed the term homeostasis and studied some mechanisms of it |
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| Maintaining constancy of internal environment |
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| set point within a certain normal range |
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| some physiologic variables where there's a desired range |
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-blood pressure -blood glucose |
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| what happens when the physiological parameters increase or decrease too much? |
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| a loop is activated to reach homeostasis |
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| how a loop to reach homeostasis is activated |
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-Sensor detects deviation from set point -Integrating center, often CNS, determines the response -Effector, often muscles or glands, produces the response; this is the target tissue |
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| detects physiological deviation from set point |
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| often the CNS, this determines the response to the physiological deviation from set point |
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| often muscles or glands, this is the target tissue that produces the response to the physiological deviation from set point |
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| How does the integrating center communicate with the effector tissues? |
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| it usually boils down to signaling patways, which can be through the nervous system or through hormones, sometimes with crossover between the two types of pathways |
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| Produces change in opposite direction to reverse the deviation so that homeostasis can be reached |
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| an example of a negative feedback pathway |
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Definition
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| Homeostasis is achieved by... |
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| negative feedback inhibition |
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| Examples of physiological parameters that are regulated by negative feedback |
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| the cells that make insulin |
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| the beta cells in the pancreas |
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| what's more common? positive or negative feedback? |
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| when positive feedback is necessary |
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| when something needs to be done urgently |
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| Examples of processes that use positive feedback |
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-cervical dilation and oxytocin -clotting cascade |
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| example of a positive feedback pathway |
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| the 4 main types of tissue in the body |
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-Muscle -Nervous -Epithelial -Connective |
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| the 3 types of muscle tissue |
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| the 2 types of nervous tissue |
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| Neurons are composed of... |
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-dendrites -cell body -axons |
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| cells that form membranes and glands |
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| hollow portion of an organ |
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| spme organs that have a lumen |
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-respiratory tract -digestive tract |
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| provide barrier between external and internal environments |
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| ______ forms the functional parenchyma of organs |
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| epithelial tissue forms the ______ of organs |
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the functional tissue of an organ as distinguished from the connective and supporting tissue
for example, in the liver, the functional parenchyma is what does the metabolizing |
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| some types of connective tissue |
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Definition
-connective tissue proper -bone -cartilage -blood |
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| this is present between connective tissue cells |
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| Cells + Extracellular Matrix |
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| Extracellular Matrix (EM) composed of... |
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| -protein fibers
-ground substance |
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| at least two primary tissues |
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| organs located in different regions of the body and perform related functions |
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| molecules that usually need help crossing cell membranes |
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| molecules that contain both polar (hydrophilic) head group and non-polar (hydrophobic) tail group |
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| -RCOO-Na+
-Detergent action |
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| some important amphipathic molecules |
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-Phospholipids -Bile acids (salts) |
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| some functions of phospholipids |
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-Cell membrane structure -Transport of lipids in the blood -Functions and mechanisms of the pulmonary surfactants -Absorption of lipids into cells -Entry of steroids into cells |
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| function of bile acids (salts) |
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Definition
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| some components of the cell membrane other than phospholipids |
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-lipids -proteins -carbohydrates |
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| Membrane proteins serve as... |
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-pumps -enzymes -receptors -energy transducers |
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