Term
|
Definition
| ACTH stimulation test; no response to ACTH with cortisol = adrenal insuf. |
|
|
Term
| may need to perform a 3day rolonged ACTH stimulation in these pts |
|
Definition
| pts on long term steroid therapy; have to wake the sleeping bear |
|
|
Term
| describe low dose dexamethasone supression test |
|
Definition
| admin low does dexamethasone at night then measure cortisol. cortisol should be supressed. elevated cortisol = cushings OR false + from obesity/depression. |
|
|
Term
| high dose dexamethasone suppression test |
|
Definition
| high dose dexamethasone suppression will supress cortisol production in PITUITARY cushings disease but not adrenal tumor |
|
|
Term
| the only two endocrine disorders that can classicaly suppressed are |
|
Definition
| Prolactinomas and PITUITARY cushings |
|
|
Term
| bitemporal hemianopsia: think |
|
Definition
| expanding pituitary neoplasm |
|
|
Term
|
Definition
| pituitary necrosis post-partum. presents most commonly as ammenorrhea. but can present years later as hypopituitary (addison's, hypothyroid, etc.) |
|
|
Term
|
Definition
1. post-partum hemmorrhage
2. DIC
3. HELLP
4. amniotic fluid embolism |
|
|
Term
| 2 causes of nephrogenic diabetes insipidus |
|
Definition
1. hypercalcemia
2. lithium |
|
|
Term
| somatomedin C levels, macroglossia, HTN, CHF, DM = |
|
Definition
|
|
Term
| prolactinomas can be suppressed with: |
|
Definition
| dopamine analog; bromocriptine |
|
|
Term
| 4 causes of hyperprolactimemia: |
|
Definition
1. prolactinoma
2. hypothyroid
3. cimetidine
4. spirinolactone |
|
|
Term
| amiodarone causes hypothyroid in __-__% |
|
Definition
|
|
Term
| fever, sed rate, thyrotoxicosis with low RAIU |
|
Definition
|
|
Term
|
Definition
|
|
Term
| anti-microsomal ab, thyroglobulin ab |
|
Definition
|
|
Term
|
Definition
| radio-iodine for most PTU in pregnancy |
|
|
Term
|
Definition
1. BB
2. steroids
3. PTU
4. super saturated potasium iodide |
|
|
Term
| tx for symptomatic euthyroid goiters |
|
Definition
| levothyroxone to TSH <1 to shrink goiter |
|
|
Term
| several distinct syndromes featuring tumors of endocrine glands, each with its own characteristic pattern |
|
Definition
| Multiple Endocrine Neoplasia; MEN1-MEN2b |
|
|
Term
|
Definition
1. pit adenoma
2. parathyroid
3. PUD (ZE syndrome)
4. pancreatic tumor |
|
|
Term
| most common cause of hypercalcemia in out-patient population |
|
Definition
| hyperparathyroid from adenoma |
|
|
Term
| symptoms of hypercalcemia |
|
Definition
1. abd moans (constipation)
2. psychic groans
3. kidney stones
4. hungry Bones |
|
|
Term
| malignancies that produce PTH-like peptide |
|
Definition
|
|
Term
| is PTH-like peptide measured as PTH in the lab? |
|
Definition
|
|
Term
| 3 causes for hypercalcemia other than malignancy and hyperparathyroid |
|
Definition
1. thiazides
2. sarcoid (produce Vit D)
3. vit D toxicity |
|
|
Term
| most common cause of secondary hyperparathyroidism: |
|
Definition
| chronic renal failure; highest PTH levels of all. caused by consistently low levels of Calcium from < production of active Vit D by the kidneys |
|
|
Term
| how does hypomag cause hypocalcemia |
|
Definition
| mag is coenzyme required for PTH synthesis |
|
|
Term
| what etiology of Cushings produces the highest ACTH levels of all. |
|
Definition
| lung CA producing ectoopic ACTH |
|
|
Term
| 3 etiologies for cushings |
|
Definition
1. pituitary
2. adrenal
3. lung ca |
|
|
Term
|
Definition
1. buffalo hump
2. moon facies
3. striae
4. osteoporosis
5. hirsuitism |
|
|
Term
| borderline hypernatremia, hypokalemia, metabolic alkalosis, HTN, high urine K+ |
|
Definition
| Conn's (primary hyperaldosteronism) |
|
|
Term
| 6 P's associated with Pheo |
|
Definition
1. Pallor (vasoctx)
2. Pressure >
3. palpitations (tachy)
4. panic (anxiety)
5. perspiration
6. Pain with HA |
|
|
Term
|
Definition
1. plasma free metanephrines
2. 24h urine for metanepherines vanilmandelic acid |
|
|
Term
|
Definition
| Alpha (clonidine) and BB... BB only will leave alpha receptors unapposed and cause HTN |
|
|
Term
| endocrine disorder associated with eosinophilia: |
|
Definition
| Addisons disease; only in about 15% of cases possible autoallergic cause |
|
|
Term
|
Definition
1. hypoNa
2. HperK
3. HypoGly
4. Met Acidosis
5. eosinophilia
6. hyperpigmentation |
|
|
Term
| mechanism of hyperpigmentation in addisons |
|
Definition
| ACTH has similar structure to MSH |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| a disease of the adrenal glands most commonly caused by the bacterium Neisseria meningitidis. The infection leads to massive hemorrhage into one or (usually) both adrenal glands.[1] It is characterized by overwhelming bacterial infection meningococcemia, low blood pressure and shock, disseminated intravascular coagulation (DIC) with widespread purpura, and rapidly developing adrenocortical insufficiency. |
|
Definition
| Waterhouse-Friderichsen syndrome (WFS) or hemorrhagic adrenalitis |
|
|
Term
| most common cause of congenital adrenal hyperplasia |
|
Definition
| 21-OH deficiency. early onset puberty |
|
|
Term
|
Definition
1. ACTH in sm cell lung CA
2. ADH in small cell lung C
3. B-hCG in choriocarcinoma
4. Calcitonin in medullary CA of thyroid
5. EPO in Renal or hepatic CA
6. PTH-like peptide in SCLungCA, BCA
7. Serotonin in carcinoid syndrome |
|
|
Term
| syndrome includes flushing and diarrhea, and, less frequently, heart failure and bronchoconstriction.[2] It is caused by endogenous secretion of mainly serotonin and kallikrein. |
|
Definition
|
|
Term
|
Definition
| 24h urine for 5HIAA (marker for serotonin metabolism) |
|
|
Term
| most common location for carcinoid tumors |
|
Definition
|
|
Term
| erectile dysfunction evaluation |
|
Definition
| if no morning wood; TSH, prolactin, testosterone level, screen for PAD |
|
|
