Term
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Definition
Inhibits enolase
Stops conversion of 2-phosphoglycerate to PEP. |
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Term
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Definition
| 1. Incorporates into G-3-P instead of phosphate. Hydrolyzed to 3-BPG and NO substrate level phosphorylation occurs = no net synthesis of ATP. |
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Term
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Definition
| 1. Inhibits Lipoic Acid Enzymes such as E2 in PDH and AKG-DH |
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Term
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Definition
| Inhibits Complex IV (Cytochrome Oxidase) |
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Term
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Definition
1. Inhibits Complex I (Direct ETC)
2. Decrease O2 use and ATP formation
Insecticides and fish poison |
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Term
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Definition
1. Inhibits Complex I
2. Decrease O2 use and ATP formation
3. Barbituates |
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Term
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Definition
1. Inhibits Complex I
2. Decrease O2 use and ATP formation
Synthetic Heroin |
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Term
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Definition
1. Inhibits Succinate in Complex II
2. Decrease O2 use and ATP formation |
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Term
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Definition
1. Inhibits Complex III
2. Decrease O2 use and ATP formation
Bacterial product |
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Term
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Definition
1. Blocks Complex IV
2. Decrease O2 use and ATP formation
Almond pits and fruit pits
Burning plastics
Gas chamber |
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Term
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Definition
1. Blocks transport of ADP from cytosol to mito matrix via Adenine Nucleotide Translocase
2. ATP builds up in mito but can't escape, and ADP can't enter.
3. ETC Slows
4. Depend on coupled PMF and ETC |
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Term
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Definition
1. Blocks ATP Synthase proton channel
2. H+ builds up in IM space
3. Depend on tightly coupled PMF and ETC |
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Term
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Definition
1. Uncoupler through opening UCP1 channel
2. Makes heat, NOT ATP |
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Term
| Hydrophobic Weak Acids (1) |
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Definition
| Uncoupler through facilitating proton transport across IMM into matrix |
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Term
| Aspirin or Pentachlorophenol (1) |
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Definition
| Uncoupler through facilitating proton transport across IMM into matrix |
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Term
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Definition
| Uncoupler through facilitating proton transport across IMM into matrix |
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Term
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Definition
1. Increases Basal Metabolic rate
2. Decreases efficiency between ETC and ATP formation |
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Term
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Definition
Bacterial Ionophore
1. Forms transmembrane pore that allows cations but not anions to travel. |
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Term
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Definition
1. Promote membrane permeability of K+, H+, and Na+.
2. Messes up ion gradient which forces Na-K-ATPase to waste ATP |
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Term
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Definition
Bacterial ionophore
1. Forms cage around K+ that allows it to freely travel across membrane |
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Term
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Definition
1. Blocks biotin absorption in intestine
2. Inhibits pyruvate carboxylase
1. Egg whites |
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Term
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Definition
| Cause RBC lysis through increasing ROS levels |
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