Term
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Definition
| viruses that enter through the digestive tract |
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Term
| What is the ultimate destination of enteric viruses? |
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Definition
| To reach the the epithelial cells of the small intestine. |
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Term
| Why is a rotavirus called a rotavirus? |
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Definition
For the Latin word for wheel. The virus looks like a wheel with spokes. |
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Term
The rotavirus's sur-name is: |
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Definition
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Term
Different flavors of rotaviruses? |
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Definition
Rotaviruses can be subgrouped and classified by the types of antibodies that bind to it. However group A is the group that actually causes most diseases. |
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Term
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Definition
| Eleven segments of double stranded RNA |
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Term
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Definition
| Three concentric protein capsids |
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Term
Outer capsid two viral proteins: |
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Definition
VP4 and VP7 VP7 makes up most of the capsid, VP4 pokes out like spikes. |
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Term
| How does a rotavirus get into a cell? |
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Definition
They don't know. It is believed that the virus uses and endosome (pinched off cell membrane) |
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Term
| How does the rotavirus get rid of its coat? |
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Definition
Again, they're not entirely sure.... But it looks as if VP4 and VP7 punch holes in the endosome. The calcium concentration within the endosome drops, and the bundles of VP7 fall apart, disintegrating the outer protein coat. |
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Term
| How do antibodies deal with a rotavirus? |
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Definition
| The clamp down on the triads of VP7, making it so that te virus, even when calcium balance is achieved, cannot disintegrate and release its genome into the cell. |
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