Term
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Definition
| include changes in the plasma proteins, sketela muscle catabolism, and increased leukocytes. |
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Term
| what do cytokines affect? |
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Definition
| the thermoregulatory center in the hypothalamus to produce fever. |
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Term
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Definition
| severe bacterial infection |
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Term
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Definition
| regeneration of tissue cells |
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Term
| what happens during connective tissue replacement and regeneration? |
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Definition
| cell migration, proliferation, and differentiation. (also, interaction with extracellular matrix) |
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Term
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Definition
| contain the functioning cells of an organ. (renal tubules, heptocytes) |
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Term
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Definition
| consist of the supporting connective tissues, blood vessels, extracellular matrix, blood vessels, and nerve fibers |
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Term
| body cell types are divided into 3 types, what are they? |
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Definition
| labile, stable, or permanent. |
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Term
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Definition
| continue to divide and replicate through life. ex. skin |
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Term
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Definition
| normally stop developing when puberty ceases. they will regerate when confronted with a proper stimulus |
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Term
| what are examples of stable cells? |
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Definition
| liver cells, kidney, smooth muscle... |
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Term
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Definition
| cannot undergo regeneration and mitotic division. nerve cells, cardiac, skeletal muscles. They will get replaced with scar tissue. |
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Term
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Definition
| glitening red, moist connective tissue. |
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Term
| what is involved with the formation of granulation tissue? |
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Definition
| new capillaries (angionesis), fibrogenesis, and the involution of scar tissue. |
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Term
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Definition
| involves the generation and sprouting of new blood vessels from pre-existing vessels |
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Term
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Definition
| the influx of activated fibroblasts that secrete ECM. (fibronectin, hyaluronic acid, proteoglycans and collagen.) |
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Term
| what makes a scar waterproof? |
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Definition
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Term
| how does scar formation occur? |
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Definition
| emigration and proliferation of fibroblasts, deposisting of ECM. collagen deposits. vascular degeration makes the scar appear pale. |
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Term
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Definition
| surgical insision that is closed. |
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Term
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Definition
| slower healing. it heals with an open wound. larger amount of scar tissue. |
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Term
| vascular phases of healing |
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Definition
| brief constriction, vasodilation, increased permiability, plasma leakage. |
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Term
| cellular phase of inflammation |
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Definition
| migration of phagocytotic WBC's tht digest foreign and broken material. |
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Term
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Definition
| phagocytosis. release of growth factors that stimulate epitheleal growth, angiogenesis, and attract fibroblasts. |
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Term
| T or F: a wound can heal without neutrophils but it can't heal without macrophages |
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Definition
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Term
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Definition
| tissue building, fibroblast is the key cell-it makes collagen and it secretes angionesis and skin cell proliferation and migration |
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Term
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Definition
| the migration, proliferation, and differentiation of skin cells to form a new layer. |
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Term
| what are the 3 pahses of wound healing? |
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Definition
| inflammatory phase, proliferation phase, remodeling phase. |
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Term
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Definition
| the wound will continue to have fibroblasts and collagen deposits to increase tensile strength. |
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Term
| how does secondary intention heal during the remodeling phase? |
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Definition
| it will undergo wound contraction which will shrink the scar size. |
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Term
| how does hypoxia affect the cell? |
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Definition
| hypoxia causes cell swelling |
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Term
| what is an example of systemic? |
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Definition
| swollen ankles from edema causes by cardiac problems |
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Term
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Definition
| swollen ankles from a broken ankle |
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Term
| what is a very good example of cellular hypertrophy? |
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Definition
| heart cells will expand due to hypertension to have more strength to pump blood. cardiac cells cant divide so it has to swell to get stronger. |
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Term
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Definition
| increased numbers of circulating leukocytes |
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Term
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Definition
| it shows where the inflammation is |
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Term
| is c reactive proteins are elevated it means that....? |
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Definition
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Term
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Definition
| layers of the skin have separated |
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Term
| what are the stages in the proliferative phase? |
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Definition
| granulation tissue, epitheliazation, collagen tissue formation, fibrous scar formation |
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