Term
| gram negative, rod shaped, stain poorly with gram; Transmitted by dog tick |
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Definition
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Term
| headache, fever, malaise, respiratory insufficiency, renal failure and shock with 40% having a rash |
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Definition
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Term
| major cause of death in Rickettsial infection induced Rocky Mountain fever |
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Definition
| Non-cardiogenic pulmonary edema causing adult respiratory distress syndrome |
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Term
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Definition
| rickettsia prowazekii (from body lice) |
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Term
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Definition
| orienta tsutsugamushi (chiggers) |
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Term
| cytoplasmic inclusions occasionally shaped like mulberries, morula, and composed of masses of bacteria seen in leukocytes |
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Definition
| Ehrlichia chaffeensis (recently discovered tick transmitted disease caused by Rickettsiales) predominantly infect neutropils. |
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Term
| cells infected in Rickettsiae causing RMSF and typhus |
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Definition
| usually vascular endothelial cells, especially in lungs and brain. Enter by endocystosis but escape before formation of phagolysosome. |
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Term
| what causes the severe manifestations of rickettsial infection? |
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Definition
| vascular leakage secondary to endothelial cell damage. Causes hypovolemic shock with peripheral edema, pulmonary edema, renal failure, and CNS (coma) |
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Term
| what is the difference between typhus and spotted fever rickettsia |
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Definition
| typhus lyse the cell, SF spread through actin-mobilized motion. |
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Term
| rash and small hemorrhages to necrosis of skin and gangrene of tips of fingers, nose, earlobes, scrotum, penis and vulva; Cuff of mononuclear inflammatory cells surrounds affected vessels; Necrosis of vessel unusual |
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Definition
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Term
| hemorrhagic rash over entire body including palms and soles. Necrosis, fibrin extravasation and thrombosis of small blood vessels. Sever forms have necrotic skin leisons of fingers, toes, elbows, ears, and scrotum. Perivascular inflmaation seen; vascular leisons produce microinfarcts in brain |
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Definition
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Term
| focal microglial proliferations with inflitrates of mixed T lymphos and mac's (in brain) |
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Definition
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