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Infection and Immunity 2- Lecture 16
Upper Respiratory Tract Infections
39
Medical
Professional
04/29/2013

Additional Medical Flashcards

 


 

Cards

Term

6 viruses that can cause the common cold

+

How to treat

Definition

Rhinovirus

Coronavirus

Adenovirus

Parainfluenza

Respiratory Syncytial (RSV)

Influenza

 

Symptomatic treatment only

Term
Symptoms and treatment of Viral Pharyngitis
Definition

Fever, sore throat, red throat, cervical lymphadenopathy

 

no antibiotics

Term
2 important viruses that cause viral pharyngitis
Definition

Adenovirus (+ other common cold agents)

Epstein-Barr virus

 

(also HIV, cytomegalovirus, coxsackievirus, and herpes simplex)

Term
3 Symptoms of bacterial pharyngitis.
Definition

Bacterial:

- sore throat, pain with swallowing

- fever

- blood in secretions

Term

7 bacteria that cause pharyngitis

- Which 2 are the most common?

Definition
Streptococcus pyogenes
Mycoplasma pneumoniae
Chlamydia pneumoniae
mixed anaerobes ( Fusobacterium)
Corynebacterium diphtheriae
Neisseria gonorrhoeae
Yersinia enterocolitica (raw milk)
Term

2 most common viral causes and 2 most common bacterial causes of Exudative Pharyngitis

 

Give them in order of most to least common

Definition

Viral:

1. Adenovirus

4. Epstein-Barr virus

 

Bacterial:
2. Streptococcus pyogenes
3. Mycoplasma pneumoniae

Term
4 Differentiating symptoms of steptococcal pharyngitis
Definition

SEVERE sore throat

Headache and Abdominal pain

NEVER hoarseness or cough

Term
Which group of strep causes streptococcal pharyngitis, and how is it treated?
Definition

Group A

 

10 days of penicillin (to prevent rheumatic fever)

Term
3 complications of streptococcal pharyngitis
Definition
scarlet fever
rheumatic fever
acute glomerulonephritis
Term

Steptococci that cause scarlet fever have what special feature? What are the 2 types of this?

 

Definition
streptococci harbor a bacteriophage that
codes for an erythrogenic toxin:
–SPE A
–SPE C
Term

3 symptoms of Scarlet Fever

 

and 1 possible complication froma severe infection

Definition

rash, circumoral pallor, strawberry tongue

 

toxic shock-like syndrome : severe streptococcal infection producing SPE A or SPE B leads to shock, renal impairment and death

Term
Who gets rheumatic fever after streptococcal pharyngitis, and why?
Definition
predisposed persons make antibody to streptococcal M protein that cross-reacts with cardiac and articular antigens
Term
4 major "Jones Criteria" for diagnosing rheumatic fever
Definition
carditis, arthritis, chorea,erythema marginatum subcutaneous nodules
Term
When rheumatic fever occurs
Definition
occurs 3 weeks after streptococcal pharyngitis
Term

When post-strep acute glomerulonephritis occurs for pharyngitis vs. skin infection

 

+ 1 major sign

Definition

10 days after pharyngitis
3 weeks after skin infection

 

coca cola colored urine

Term
How to treat post-strep acute glomerulonephritis
Definition

Don't treat, it spontaneously resolves in weeks

 

No prophylaxis needed, recurrence is rare

Term
How to treat Rheumatic Fever (4)
Definition

penicillin to eradicate infection
aspirin for arthritis
prednisone for carditis

 

Also, need 20 day penicillin prophylaxis to prevent recurrence

Term
Quinsy is aka ___
Definition
Peritonsillar abscess
Term

What is Ludwig's angina? (3)

 

Definition

Abscess in:

submaxillary space
sublingual space
submandibular space

Term
Symptoms of Epiglottitis
Definition
Infections with fever, drooling, and airway obstruction
Term
Who used to get epiglottitis (before vaccines were made) and from what microbe?
Definition

Children

 

From Haemophilus influenzae type b

Term
Who gets epiglottitis today, and from what 2 microbes?
Definition

Adults

 

From:

Streptococcus pneumoniae
Streptococcus pyogenes

Term

Laryngotracheobronchitis

- is aka ___

- symptoms in children vs. adults

- when it occurs

- what microbe causes it

- how to treat (2)

Definition

- Aka croup

 

- Children: barking cough and inspiratory stridor
–Adults: laryngitis only

 

- Fall and Winter

 

- From Parainfluenza

 

Mild: symptomatic treatment, humidified air

Severe: steroids

Term
What is Tracheobronchitis?
Definition
Cough that lasts for 3 to 6 weeks without any respiratory distress.
Term
3 microbes that cause Tracheobronchitis in children
Definition
rhinovirus, parainfluenza, RSV
Term
2 microbes that cause Tracheobronchitis in adolescents
Definition
Mycoplasma pneumoniae and
Chlamydia pneumoniae
Term
5 microbes that cause Tracheobronchitis in adults
Definition
influenza, enteroviruses,
Haemophilus influenzae,
Moraxella catarrhalis
Streptococcus pneumoniae
Term
How to treat Tracheobronchitis in adults
Definition
in healthy adults -humidification and cough suppressants
in chronic disease (COPD) -antibiotics
Term
What problems does respiratory syncytial virus cause?
Definition

Bronchiolitis in infants

 

Can be fatal in premies and babies w/ cardiac/pulm problems

Term
How do we treat respiratory syncytial virus?
Definition
passive prophylaxis with monoclonal Ab (Synagis)
ribavirin used for treatment of severe case
Term
5 signs/symptoms of influenza
Definition

Acute onset

High fever

Pharyngitis

Crackles/wheezes in lungs

Low WBC count

 

NO GI SYMPTOMS

Term
2 different combination drugs used to treat influenza, and who gets it and when
Definition
Oseltamivir (Tamiflu)/zanamavir
amantidine/rimantidine in high-risk if
started within 24 hours
Term
3 microbes that cause acute sinusitis
Definition
pneumococcus, H. flu, streptococci
Term
2 microbes that cause acute sinusitis to become chronic
Definition
acute sinusitis microbes + staphylococcus and anaerobes
Term

2 acute sinusitis symptoms

 

How to treat mild vs. moderate/sever

Definition

- localized facial pain
- purulent nasal drainage (>10 days in kids)

 

mild: antihistamines
moderate to severe: antibiotics (amoxicillin or
amoxicillin/clavulanate)

Term
4 chronic sinusitis symptoms
Definition
nasal obstruction
poor appetite
night time cough
fatigue
Term
3 bacteria that cause otitis media
Definition
S. pneumoniae
H. flu
M. catarrhalis
Term
How to treat otitis media (4)
Definition
antibiotics only
–amoxicillin (80 mg/kg)
–amoxicillin/clavulanate
–cefuroxime
–clarithromycin
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