Term
| What Nitrofurantoin is used for |
|
Definition
To treat cystitis UTIs, escpecially from E. coli and S. saprophyticus
(concentrates well in urine but not elsewhere) |
|
|
Term
| What Fosfomycin is used for |
|
Definition
| To treat uncomplicated UTIs from E. coli and Enterococcus faecalis |
|
|
Term
|
Definition
| Is an analog of PEP, blocks bacterial synthetases |
|
|
Term
| What Methenamine is used for + how |
|
Definition
| Urinary antiseptic that works by releasing formaldehyde at pH <5.5 |
|
|
Term
| What pathogen is usually resistant to Methenamine and why? |
|
Definition
| Proteus, because is alkalizes urine |
|
|
Term
| What is Pyridium used for? |
|
Definition
| Used in conjunction with antibiotics for its local analgesic effects on the urinary tract in interstitial cystitis |
|
|
Term
| What are some possible adverse effects of Pyridium? (4) |
|
Definition
| Pigment change, reddish urine, GI, hemolytic anemia in G6PD deficiency |
|
|
Term
What Fidaxomicin is used for
+
its MOA |
|
Definition
For C. difficile infections
Inhibits bacterial RNA polymerase |
|
|
Term
| Possible adverse effects from Fidaxomicin (5) |
|
Definition
GI upset
flatulence
GI obstruction
increased hepatic enzymes
Rash |
|
|
Term
| What Polymixins are used for (3) |
|
Definition
| Psuedomonas, Acinetobacter, enterobacteriaceae |
|
|
Term
|
Definition
| Detergent action on bacteria's outer membrane |
|
|
