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Details

Indirect acting Cholinomimetic Drugs
N/A
8
Pharmacology
Professional
11/16/2010

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Cards

Term
ACETYLCHOLINESTERASE inhibitors
Definition
Cause inhibition of Achesterase, increase ACh levels, and increase ACh action on post-synaptic nerves.
Term
EDROPHONIUM
Definition
Short-acting alcohol with a quaternary ammonium group
Blocks Cholinesterase
Used for myasthenia gravis, ileus, arrythmias
Term
NEOSTIGMINE
Definition
Carbamate with quaternary ammonium
Used to treat Myasthenia gravis, ileus
Term
DEMECARIUM
Definition
Carbamate with quaternary ammonium
used to treat glaucoma
Term
AMBENONIUM
Definition
Carbamate with quaternary ammonium
Used to treat myasthenia gravis
Term
PYRIDOSTIGMINE
Definition
Quaternary ammonium group
Used to treat myasthenia gravis
Reversibly blocks AChesterase as a prophylactic measure against soman poisoning
Term
PHYSOSTIGMINE
Definition
Carbamic acid + phenol + tertiary ammonium
Used to treat glaucoma
Term
DONEPIZIL AND TACRINE
Definition
Carbamic acid and tertiary ammonium
Can cross BBB, used to treat Alzheimer's
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