Term
| If the ___ _ ___ is removed at birth, the chicken does not make antibody |
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Definition
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Term
| The paracortical area of a lymph node is a __ area. |
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Definition
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Term
| Both T and B cells can be ___ cells. |
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Definition
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Term
| The cortical area of a lymph node is a ___ area. |
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Definition
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Term
| ____ are found on B cell surfaces. |
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Definition
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Term
| ____ secrete lymphokines like MIF and CF. |
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Definition
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Term
| T-dependent Ag are usually ___. |
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Definition
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Term
| IgE has a sedimentation coefficient of __. |
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Definition
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Term
| The immune response usually ___ distinguish "self" from "not-self" antigens. |
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Definition
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Term
| A single plasma cell can synthesize Ig for __ one antigenic specificity. |
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Definition
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Term
| In the __ __, both antigen and antibody have to be polyvalent molecules. |
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Definition
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Term
| ___ ___ are found in both IgM and secretory IgA. |
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Definition
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Term
| Endogenous Ag are presented by ___, whereas exogenous Ag are presented by MHC--Class II. |
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Definition
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Term
| The Ab half-life of IgM is _____ than that of IgG |
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Definition
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Term
| The anamestic response is a ___ Ab response by IgG. |
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Definition
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Term
| Antibodies are ____ globulins. |
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Definition
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Term
| _____ rather than Lamba light chains are most often found as part of an Ig molecule (almost 70%) |
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Definition
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Term
| Serum IgA and secretory IgA have _____ molecular weights. |
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Definition
| different (serum--160,000 mw; secretory 385,000 mw) |
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Term
| _____ involves CD28 on T-cells with B7 on Ag-presenting cells. |
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Definition
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Term
| Ab have a ___ helical as secondary protein structure. |
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Definition
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Term
| Both humoral immunity and CMI responses would be reduced by a _____ number of TH1 and TH2 cells. |
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Definition
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Term
| T-independent Ag are usually___. |
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Definition
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Term
| The ___genes of Kappa and Lambda light chains are identical. |
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Definition
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Term
| ____ genes are required to synthesize a complete Ig molecule. |
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Definition
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Term
| The amount of IgG formed after a second exposure to an Ag is ___ than that formed after a first exposure to the same Ag. |
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Definition
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Term
| Agglutination is best done by ___. |
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Definition
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Term
| Surface receptors for Ag on B-cells are ___ and ___. |
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Definition
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Term
| T-____ and T- ____ cellls recognize specific Ag. |
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Definition
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Term
| The ____ systems and ____ decline with age. |
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Definition
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Term
| ______ increase phagocytosis. |
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Definition
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Term
| Precipitation and exotoxin neutralization functions are best done by __ |
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Definition
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Term
| An IgG primary response becomes T-independent as a ______ ___. |
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Definition
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Term
| In a primary resonse, ____ is the first Ab class produced. |
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Definition
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Term
| In the Lattice Hypothesis, ___ precipation occurs in Equivalence Zone. |
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Definition
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Term
| Examples of secondary lymphnoid tissues are ___ and___ |
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Definition
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Term
| In ___, you break tolerance (immunological unresponsiveness) to "self" Ag. |
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Definition
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Term
| The C genes coding for heavy chains would ___ differ for IgG and IgM. |
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Definition
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Term
| Metchnikoff discovered ____ and __. |
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Definition
| the process of phagocytosis and cellular immunity |
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Term
| Ab are present in ___concentrations in the blood than in lymphatic system. |
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Definition
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Term
| ____ __ lies beneath mucosal surfaces and is responsible for secretory IgA production. |
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Definition
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Term
| Lymph nodes and thymus are two __- lymphoid tissues. |
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Definition
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Term
| _____ present antigenic peptides to T-lymphocytes. |
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Definition
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Term
| T and B lymphocytes require at least two ____ ___ for activation |
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Definition
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Term
| ___ and ____ require MHC moleucles to present them with Ag peptides. |
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Definition
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Term
| Peyer's patches lymphoid tissue is found in ____. |
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Definition
| ileum of the small intestine |
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Term
| MHC molecules display ___ |
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Definition
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Term
| ____ immunity does not hve a memory response. |
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Definition
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Term
| ___ and ___ are both Ag-presenting cells of T-dependent Ag. |
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Definition
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Term
| AB are synthesized and secreted principally by this cell type |
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Definition
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Term
| Ab class having the greatest molecular mass |
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Definition
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Term
| Receptor recognizes both self (MHC) and nonself AG determinants |
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Definition
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Term
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Definition
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Term
| substance when mixed with Ag increases an immune response |
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Definition
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Term
| Fragment of Ig molecule containing only heavy chains |
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Definition
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Term
| Ig class found in greatest concentraction in human serum |
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Definition
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Term
| Ab class that predominates in saliva and breast milk |
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Definition
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Term
| Important characteristic of adaptive immune response |
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Definition
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Term
| Fragment of Ig molecule taht binds Ag determinant |
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Definition
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Term
| Bond most important in holding L and H chains together in Ig molecule |
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Definition
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Term
| Lymphocyte that recognizes peptide Ag presented by MHC, Class I |
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Definition
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Term
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Definition
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Term
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Definition
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Term
| B memory response is mainly of what Ab class |
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Definition
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Term
| Chemical force important in the Ag/Ab union |
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Definition
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Term
| IgM, a 19S macroglobulin, exists in this structure |
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Definition
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Term
| Ag found on surfaces of all mammalian cells except RBC |
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Definition
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Term
| Interleukin01 produced by this specific cell type |
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Definition
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Term
| Interleukin-2 produced by this specific cell type |
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Definition
| T-delayed hypersensitivity |
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Term
| Multiple Myeloma involves unregulated proliferation of this cell type |
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Definition
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Term
| Considered master organ of immune system |
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Definition
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Term
| Antigens used in precipitin type reactions are referred to as being |
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Definition
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Term
| What organic molecule class is not immunogenic? |
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Definition
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Term
| An opsonizing Ab has the function of |
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Definition
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Term
| An opsonizing Ab has the function of |
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Definition
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Term
| An Ab molecule has teh distinguishing characteristic of being |
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Definition
| monospecific and multivalent |
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Term
| In the indirect immunofluorescent test for identification of a specific human infectious organism,fluorescein (FITC) is conjugated to __ |
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Definition
| Ab specific to human gamma globulin |
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Term
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Definition
| cann collaborate with T-cells if needed |
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Term
| The clonal selectrion theory of Ab formation implies that |
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Definition
| the B-lymphocyte is genetically programmed with a surface receptor pattern complementary to the specifice Ag, and the Ag combines with the Ig receptor that has teh right complementary pattern |
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Term
| A lack of T-suppressor cells my explain |
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Definition
| the formation of Ab against self Ag and auto immune disease |
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Term
| List the 5 subpopulations of Thymic Lymphocytes |
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Definition
| Hint: The hyper helper remembers to regulate the toxins. 1. T-delayed hypersentivity 2. T-helper 3 T-memory 4. T-regulatory/suppressor 5. Cytotoxic T-lymphocyte |
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Term
| Th1; CD4+ ; produces IL2 which produces lymphokines that directed CMI, MO; MHC presents T-dependent Ag |
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Definition
| T-delayed hypersensitivity |
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Term
| Th2; CD4+; Helper for B-cell cooperation; Antibody response; MHCII presents Ag to it |
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Definition
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Term
| CD8+; primary roles is to kill virus infected cells and tumor cells; MHCI presents T-dep Ag thru DC |
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Definition
| Cytotoxic T-lymphocyte aka. CTL aka. T-cytotoxic |
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Term
| CD4+ and CD25+; supresses TH1, TH2, and CTL/ |
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Definition
| T-regulatory or T-suppressor |
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Term
| CD4+ or CD8+; long term memory response |
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Definition
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