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Immunology
Exam One Material
28
Immunology
Undergraduate 4
09/26/2015

Additional Immunology Flashcards

 


 

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Term
Immunology definition
Definition
not just defense against microorganisms
not just defense
most fundamental definition based on distinguishing self from non-self
Term
Four classes of pathogens
Definition
1. bacteria (extracellular/intracellular)
2. viruses (intracellular)
3. parasites
4. fungi
Term
Antibody
Definition
is bounded specifically to toxins and neutralize them
Term
Adaptive Immunity
Definition
developed during the lifetime of an individual
lifeleong protective immunity
slow to develop
Term
Innate immunity
Definition
nonspecific
no long lasting immunity against specific immunity
Term
Five types of white blood cells
Definition
neutrophils
lymphocytes
monocytes
eosinophils
basophils
Term
Two types of lymphocytes
Definition
b-cells
t-cells
Term
four types of phagocytic cells
Definition
dendritic cells
macrophages
neutrophils
eosinophils
Term
dendritic cells
Definition
antigen-presenting
lymphatic tissue
presents antigens to helper-t cells, initiating a primary immune response
Term
macrophages
Definition
functions in innate immunity by destroying microbes and in acquired immunity as an antigen presenting cell
Term
neutrophils
Definition
most abundant white blood cell
circulated in blood
attracted by signals in infected tissue
phagocytic
tend to self destruct ass they destroy foreign invaders (short life span)
Term
eosinophils
Definition
destroy parasitic organisms
play major role in allergic reactions
mucosal surfaces
low phagocytic activit
destructive enzymes
Term
Mast cell
Definition
produces histamine and other molecules that trigger inflammation in response to infection and in allergic reactions
Term
natural killer cells
Definition
can kill tumor cells and virus infected cells ass part of innate immunity
detection of ABNORMAL ARRAY OF SURFACE PROTEINS
Term
lymphocytes
Definition
B cells
T cells
Term
B cell lymphocyte
Definition
mature in the bone marrow
Term
T cell lymphocyte
Definition
migrate from the bone marrow and migrate to the thymus to mature
Term
Cytokine
Definition
signaling molecule
group of small proteins secreted by number of cells types that regulate the function of other cells
Term
Cells that release cytokines
Definition
macrophages
neutrophils
helper t cells
Term
interferons
Definition
proteins that provide innate defense by INTERFERING WITH VIRAL INFECTIONS
Term
Interferon alpha and interferon beta
Definition
secreted by virus infected cells, help nearby cells resist viral infection
Term
Interferon gamma
Definition
secreted by t-cells
helps to activate macrophages
Term
Antibodies
Definition
a protein secreted by plasma cells (differenetiated B cells) that binds to a particular antigen
ANTIGEN IS ANOTHER WORD FOR IMMUNOGLOBULIN
Term
Major histocompatibility complex molecule
(MHC)
Definition
host protein that functions in antigen presentation
Term
Antigen
Definition
any sustance that elicits a response from a b cell or a t cell
Term
T cell's role in adaptive immunity
Definition
destroy infected cells to eradicate intracellular pathogens
all viruses, some bacteria
INTRACELLULAR
Term
B cell's role in adaptive immunity
Definition
B cells secrete antibodies to attack extracellular pathogens
most bacteria
EXTRACELLLAR
Term
T cell receptor (TCR) creation
Definition
V segment
D segment
J segment
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