Term
|
Definition
| binds cyclophilins, blocks differnetiaotna dn activaiton of T cells by inhibiting calcineurin, thus preventing production of IL2 |
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Term
| nephrotoxicity preventable with mannitol |
|
Definition
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Term
|
Definition
| binds FK-binding proetin inhibiting secretion of IL2 |
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
| inhibits mROT ; inhibits T cell proliferation to IL2 |
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Term
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Definition
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Term
|
Definition
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|
Term
| precursor to 6-mercaptopurine |
|
Definition
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|
Term
| metabolized by xanthine oxidase thus toxic effects may be increased by allopurinol |
|
Definition
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Term
|
Definition
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|
Term
| cytokine release syndrome |
|
Definition
|
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Term
|
Definition
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Term
|
Definition
| anemis, expeially in renal failure |
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Term
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Definition
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Term
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Definition
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Term
|
Definition
| hept B and C, kapsois leukemias, malignant melanoma |
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
| infliximab, adalimunab, etanercept |
|
|
Term
| monoclonal ab to glycoprotein IIb/IIIa |
|
Definition
|
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Term
|
Definition
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Term
|
Definition
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Term
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Definition
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|
Term
| prevent acute transplant rejection |
|
Definition
| muromonab, daclizumab (renal) |
|
|
Term
| crohn's, psoriatic arthritis, RA |
|
Definition
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|
Term
| prevent cardiac ischemia in unstable antina |
|
Definition
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|
Term
|
Definition
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|
Term
| b cell non-hodgkin's lymphoma |
|
Definition
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Term
|
Definition
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