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Immunology Review
Jeopardy Questions
50
Immunology
Intermediate
09/25/2016

Additional Immunology Flashcards

 


 

Cards

Term
Epitope
Definition
The part of the antigen that binds the immunoglobulin molecule
Term
IgM
Definition
The largest immunoglobulin
Term
Of IgM and IgG, which one is better at precipitation
Definition
IgM
Term
Of monomeric or dimer, the immunoglobulin that is important in secretions
Definition
Dimeric
Term
Phagocytosis
Definition
The name of the process when a cell engulfs a bacteria to destroy it
Term
The reason not to take antacids everyday
Definition
decreases pH (a natural barrier for invasion of bacteria)
Term
Cell that has CD 19, 20, & 21
Definition
B cell
Term
Of proteins, polysaccharides, and lipids which is least immunogenic
Definition
lipids
Term
A hapten is combined with this for an effective immunization
Definition
Carrier molecule
Term
What are two major families of antimicrobial peptides?
Definition
Cathelicidins and Defensins
Term
What do PAMP bind to?
Definition
PRR
Term
The thymus is biggest when?
Definition
Puberty
Term
What are three common PAMPs?
Definition
LPS, terminal mannose, unmethylated DNA, ss and dss RNA, flagella
Term
What is the immunoglobulin for allergy?
Definition
IgE
Term
Of self-antigens, what is the most antigenic?
Definition
Proteins
Term
Part of the innate system?
Definition
Sneeze
Term
MALT stands for?
Definition
Mucosal associated lymphatic tissue
Term
Term from the Greek, that means "to prepare for food"
Definition
opsonin
Term
The immunoglobulin in secretions
Definition
IgA
Term
Type of T cell with which the MHC Class I is associated
Definition
CD8
Term
Knockout mice weren't perfect for showing what a cytokine did because?
Definition
Redundant (two or more cytokines do the same job)
Term
When two molecules that are different bind the same?
Definition
Cross reactivity
Term
Of primary and secondary, which includes the bone marrow and thymus?
Definition
Primary
Term
The cell that is mostly nucleus, and is key to the acquired immune system?
Definition
Lymphocytes
Term
A paracrine response is defined as
Definition
When one cell signals a nearby cell
Term
The chain that holds IgA dimer and the IgM pentamer together
Definition
J chain
Term
The marker on an immunoglobulin that is genetically linked and inherited
Definition
allotype
Term
Parts that exist after papain digestion of IgG
Definition
2 Fab and 1 Fc
Term
Antibody pieces after pepsin digestion
Definition
(Fab)2 and fragments of the Fc region
Term
The name of the compounds that cause cells to go to a site
Definition
Chemotaxins
Term
Of class I and class II molecules, the one that binds the longer amino acid sequence
Definition
Class II
Term
The antigen-binding cleft on the class I molecule is between these regions of the molecule
Definition
Alpha-1 and Alpha-2
Term
The place where the chicken B cells mature
Definition
Bursa
Term
The name of the bag containing the bacteria that is being digested after phagocytosis
Definition
phagolysosome
Term
The efficiency of an assay when 45 people tested positive out of 50 that were positive and 40 people tested negative out of 50 that were negative
Definition
5%
Term
The lymphocyte that is not antigen specific
Definition
Natural killer cell
Term
The activated innate lymphocyte that is involved in antitumor response
Definition
LAK
Term
Mom is be HLA A10, A3, B5, B7, and Dad is A25, B8, A33, and B55. Can a child that is A10, B5, A25, B8 be theirs?
Definition
Yes
Term
If there were 100 V regions, 10 D regions, and 5 j regions on the heavy chain coding region. 20 V regions and 10 J regions on the kappa light chain coding region, the number of different antibody molecules that could be made with the kappa light chain is
Definition
1 million
100 x 10 x 5 = 5000 and 20 x 10 = 200
Then 5000 x 200 = 1 million
Term
The fluorescent-activated cell sorter measures this to determine how big a cell is
Definition
forward scatter
Term
What is the final dilution of a 1:10 dilution followed by a 1:2 dilution?
Definition
1:20
Term
The sensitivity of a test when 60 people tested positive out of 120 people that were positive?
Definition
50%
Term
The specificity of a test when there were 40 people who tested negative out off 50 people that were negative
Definition
Term
The third tube in a 2 fold-serial dilution when the first tube is 1:2
Definition
1:8
Term
An acute phase reactant that results in S. pnemonia, cardiac arrest
Definition
CRP
Term
An acute phase reactant that helps clear a bruise
Definition
haptoglobin
Term
The cell with CD4 and CD3 on its surface
Definition
T Helper cell
Term
Name of any of the secretions that are involved in innate immunity
Definition
tears, earwax
Term
Antibody pieces after urea and mercaptoethanol
Definition
heavy and light chains
Term
Of class I and class II molecules, the one that has invariant chains bound to it until it is in the lysosomal compartment
Definition
Class II
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