Term
| What are the B cell mitogens? |
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Definition
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Term
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Definition
Low conc. of LPS
Con A
PHA
PWM |
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Term
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Definition
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Term
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Definition
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Term
| Chemotactic for monocytes |
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Definition
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Term
| Chemotactic for eosinophils |
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Definition
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Term
| Helps converts TH0 to a/i Tregs |
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Definition
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Term
| Triggers production of enzymes that hurts virus replication |
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Definition
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Term
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Definition
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Term
| Amplification factor for TH17 |
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Definition
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Term
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Definition
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Term
| Isotype switching for IgE |
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Definition
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Term
| Decreases production of Type 1 cytokines |
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Definition
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Term
| T-cell develop. in thymus |
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Definition
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Term
| Growth factor for THp cells |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| APC that LFA-1 and MAC-1 act on? |
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Definition
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Term
| APC for LFA-1 (CD11a & CD18) by itself? |
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Definition
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Term
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Definition
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Term
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Definition
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Term
| APC for CD28 and CD152 (CTLA-4) |
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Definition
| CD80 & CD86 (B7-1 & B7-2) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Function of LFA-1 (CD11a & CD18) and MAC-1 (CD11b & CD18)? |
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Definition
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Term
| Function of P-selectin and E-selectin? |
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Definition
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Term
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Definition
| Adhesion for transmigration |
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Term
| Somatic mutation, affinity maturation, and Isotype Switching? |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Comp. pathway specific for bacteria? |
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Definition
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Term
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Definition
| Terminal (commom pathway) |
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Term
| C3b, C3, C5, Factor B, Factor D |
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Definition
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Term
| Complement and intrinsic coagulation pathway linked by? |
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Definition
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Term
| CH50 is hemolytic test for? |
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Definition
| Classical complement pathway |
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Term
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Definition
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Term
| Antibody that activates classical pathway? |
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Definition
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Term
| Antibody that activates classical pathway? |
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Definition
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Term
| Antibody activates alternative pathway |
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Definition
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Term
| Antibody with half life of 1 week? |
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Definition
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Term
| Antibody with half life of 3 weeks? |
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Definition
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Term
| Abs expressed on naive, immature B cells? |
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Definition
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Term
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Definition
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Term
| LFA-3. ICAM-1, MHC Class 2, CD80, CD86, CD40 |
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Definition
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Term
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Definition
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Term
| First Ab always secreted in immune response? |
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Definition
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Term
| Displays antigenic fragments displayed on phagolysosome |
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Definition
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Term
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Definition
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Term
| Function of CD152 (CTLA-4) |
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Definition
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Term
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Definition
| Enhanced transcription and stabilization of IL-2 , costimulation |
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Term
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Definition
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Term
| Expressed on antigen presenting cells? |
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Definition
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Term
| Expressed on all nucleated cells? |
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Definition
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Term
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Definition
| Binds iron and decreases microbial growth |
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Term
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Definition
| Destroys muramic acid in bacterial cell walls |
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Term
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Definition
| Permeablize bacterial and fungal membranes |
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Term
| Myeloperoxidase (lysosomal enzyme) does what? |
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Definition
| Needed to make hypochlorite, which halogenates bacterial cell walls |
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Term
| Main role of CD4+ T cells is? |
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Definition
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Term
| NAlP3 Inflammasome does what? |
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Definition
| Secretes matured IL-1 and IL-18 |
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Term
| Process by which one antigen is bound by two antibodies? |
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Definition
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Term
| Ab involved with J chain? |
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Definition
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Term
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Definition
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Term
| Ab invovled with isohemagluttinins? |
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Definition
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Term
| Which Ab can cross placenta? |
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Definition
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Term
| 3 characteristics of adaptive immune system? |
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Definition
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Term
| Sequence of most immunogenic antigens? |
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Definition
PPLS
Proteins, polysacc, lipids, nucleic acids |
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Term
| Site on antigen that is recognized by lymphocytes? |
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Definition
| Epitope or antigenic determinant or determinant |
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Term
| Plays an important role in inflammation |
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Definition
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Term
| Activates macrophages to secrete cytokines and chemokines |
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Definition
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Term
| Activates endothelial cells to secrete IL-8 and MCP-1 |
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Definition
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Term
| Act on hypothalamus to induce fever and lower bp, leading to shock |
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Definition
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Term
| Activate endothelial cells to de novo express ICAM-1, ICAM-2, VCAM-1, and E-Selectin? |
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Definition
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Term
| Enchances NADPH Oxidase activity |
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Definition
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Term
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Definition
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Term
| Growth factor for T cells |
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Definition
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Term
| Enhances NK cell cytotoxicity |
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Definition
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Term
| Plays a role in pCTL to CTL differentiation |
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Definition
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Term
| Required to isotype swicth to IgE |
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Definition
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Term
| Anything to do with eosinophils |
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Definition
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Term
| In presence of TGF Beta, helps in differentiation of Thp cells to TH17 cells |
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Definition
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Term
| Hematopoiesis - Role for B and T cell differentiation |
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Definition
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Term
| Activates NK cells to secrete IFN Gamma |
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Definition
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Term
| In lung mediator of allergic asthma |
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Definition
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Term
| Plays a role in helminth infections (nematodes-round worms) |
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Definition
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Term
| Chemotactic for neutrophils |
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Definition
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Term
| Role in fungal infections and extracellular bacterial infections |
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Definition
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Term
| Induces expression of proinflammatory cytokines and chemokines from a lot of cells and metalloproteinases |
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Definition
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Term
| Growth factor for TH17 cells |
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Definition
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Term
| Proinflammatory, elevated in rheumatoid arthritis and psoriasis |
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Definition
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Term
| Helps to differentiate Thp cells to Th17 cells |
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Definition
| IL-1, IL-6, IL-23, and TGF Beta |
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Term
| Made up of p19 and p40 subunits |
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Definition
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Term
| Elevated in MS, psoriasis, and Crohn's disease |
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Definition
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Term
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Definition
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Term
| Upregulated in intestinal parasite infections |
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Definition
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Term
| Member of alarmin family and released when endothelial cells or epithelial cells undergo damage |
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Definition
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Term
| In dysregulated form, contributes to asthma, arthritis, and inflammatory bowel disorder |
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Definition
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Term
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Definition
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Term
| Promotes pCTL to CTL differentiation |
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Definition
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Term
| Enhances expression of Class 1 MHC on nucleated cells and expression of Class 2 MHC on APCs |
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Definition
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Term
| Triggers prod. of enzymes that interfere with replication of some viruses |
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Definition
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Term
| Inhibits T-cell proliferation |
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Definition
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Term
| Increases prod. of Class 1 MHC on nucleated cells |
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Definition
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Term
| Most powerful down regulator of iNOS |
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Definition
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Term
| Critical for diff. of TH0 cells to a/i Tregs |
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Definition
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Term
| Role in mobilization and activation of dendritic cells |
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Definition
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Term
| Role in diff. of myeloid progenitor to GM-progenitor |
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Definition
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Term
| Role in diff. of GM progenitor to granulocyte/neutrophil |
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Definition
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Term
| Role in diff. of GM progenitor to monocyte |
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Definition
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