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Immunology MHC Classes
Table 3.2
10
Immunology
Intermediate
09/25/2016

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Term
MHC Class I molecule reacts with what type of T cell?
Definition
CD8+ cytotoxic T cells
Term
What type of antigen does MHC Class I react with?
Definition
Endogenous (from inside the cell as in an infected cell)
Term
MHC Class I molecule is on what cells?
Definition
All nucleated cells in the body
Term
MHC Class I molecule interacts with peptides of what length?
Definition
8-10 amino acids long
Term
Where is the antigen added to the MHC Class I molecule?
Definition
In the Golgi
Term
MHC Class II molecule reacts with what type of T cell?
Definition
CD4+ T Helper cell
Term
What type of antigen does MHC Class II react with?
Definition
Exogenous (picked up from the environment)
Term
MHC Class II molecule is on what cells?
Definition
APC cells such as cells of the monocyte-macrophage lineage, B cells, and dendritic cells
Term
MHC Class II molecule interacts with peptides of what length?
Definition
13-18 amino acids long
Term
Where is the antigen added to the MHC Class II molecule?
Definition
Endosomal compartment after invariant chain removal
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