Term
| Antibodies that increase phagocytosis are called |
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Definition
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Term
| Based on antigenic differences in ____chains, antibodies have been divided into the following classes |
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Definition
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Term
| Quantitatively the second largest class of immunoglobulins in human serum is |
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Definition
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Term
| IgA immunoglobin occurs in |
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Definition
| serum, mucous secretions, saliva, urine, gastrointestinal and genitourinary tracts, and human milk |
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Term
| IgM immunoglobulins are the ___ antibodies to be detected after the injection of an antigen, highly lethal to __________ bacteria in C', and play an important _____ role in the early stages of infection |
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Definition
| first; gram negative; protective |
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Term
| Antibodies are chiefly excreted by |
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Definition
| lymphocytes (b cells that have become plasma cells) |
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Term
| According to current ideas about the macrophage, its role in Ab synthesis may be to act as an ____ cell to which the Ag, B c, and Tc can act together. |
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Definition
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Term
| List 4 tests that detect Ab in serum. |
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Definition
| 1. Precipitation reaction 2. Agglutination reaction 3. Complement fixation test 4. IFA test |
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Term
| In relation to in vitro measurement of cellular immunity it can be stated that in the presence of a specific antigen, sentitized Tc release a ___; migration of MO from a capillary tube is _____by the substance, and ____ is produced only by sensitized Tc. |
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Definition
| Soluble substance; inhibited; MIF |
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Term
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Definition
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Term
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Definition
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Term
| In relation to in vivo measurement of cellular immunity, it can be stated that it aids in the ____ of many infectious diseases, an ____ is injected into the skin of a sensitized individual and the intensity of the reaction is observed, but a person who has never been in contact with the Ag will show _____. |
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Definition
| diagnosis; antigen; no reaction |
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Term
| In the presence of Ag, sensitized T lymphocytes (TdH) produce a chemotactic factor that will attract |
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Definition
| macrophages, eosinophils, mast cells, and neutrophils |
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Term
| Cellular immmunity can be passive transferred via |
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Definition
| Transfer of T lymphoctes (TF) |
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Term
| What can be used to prevent the rejection of a transplanted organ? |
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Definition
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Term
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Definition
| killed pathogenic organisms, living avirulent organisms, and formulin-treated exotoxins (??) |
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Term
| Reduction of circulating neutrophils at the time of induction of an Arthus rection |
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Definition
| leads to suppression or decrease of the reaction |
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Term
| What immunoglobulin class is concerned with sensitization of man for local and systemic anaphylactic reactions |
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Definition
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Term
| The release of vasoactive amines by antigens results from the sensitization of _________ with anaphylactic Ab bound to its cell membrane |
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Definition
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Term
| Arthus reaction can be transferred passively by |
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Definition
| serum from immune animals |
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Term
| List 4 diagnostic tests useful in establishing whether in immune deficiency state is dues to a Tc or a Bc defect: |
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Definition
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Term
| List 4 diagnostic tests useful in establishing whether an immune deficiency state is due to a Tc or Bc defect. |
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Definition
(???) 1. Serum immunoglobulin levels (Bc) 2. Skin tests for common allergies (Tdh) 3. Lymphocyte stimulation by non-specific mitogens 4. Skin tests for common fungi
the other option that I think is wrong, but don't know for sure: serum complement levels |
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Term
| An animal is immunized with an innoculum of allogenic tumor cells which are promptly rejected by an adequate immune response. When tumor cells bearing the same H2 Ag as the immunized cells are mixed in vitro, in the absence of added complement, with spleen B cells from the immunized animals, the target cells are killed by |
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Definition
| sensitized thymus derived (t) cells |
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Term
| Delayed hypersensitivity between syngenetic guinea pigs can be transferred passively from a sensitized subject to a normal subject with |
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Definition
| Thymus derived peripheral lymphocytes and Transfer factor |
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Term
| Which biological funtion(s) as a result of complement fixation is produced by the enzymatic action of C3 convertase only |
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Definition
| Opsonization and chemotaxis of neutrophils |
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Term
| The inflammatory infiltrate which characterizes delayed hypersensitivity reaction is constituted by |
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Definition
| very few specifically sensitized lymphocytes and many macrophages with few other lymphocytes |
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Term
| In the fixation of C' by the classical pathway, ___ Ab are more efficient than IgG, ___ does not fix C', ___ is recognition unit for IgM and IgG. |
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Definition
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Term
| Neonatal thymectomy in a mouse may result inmarked _______ in circulating lymphocytes, marked ____ in the population of paracortical lymphocytes, and marked ____ or homograft or allograft rejection. |
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Definition
| decrease; decrease; impairment |
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Term
| The mode of action of antihistamines in relieving the symptoms of allergy is by |
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Definition
| blocking histamine binding to cell membranes |
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Term
| Limited digestion of the IgG molecule by pepsin results in |
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Definition
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Term
| Hybridomas are produced by union of the nuclei of a myeloma tumor cell and |
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Definition
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Term
| What organic group is not immunogenic? |
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Definition
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Term
| The stem cells for B and T lyphocytes populations are found in |
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Definition
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Term
| The male heterozygous for Rh factor mates with and Rh negative female. On the basis of genetic theory, it could be predicted that ___ of offspring would be Rh positive. |
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Definition
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Term
| Immunogenetic control determines the amount of __ formed, response to an ___, particular class of ___ formed, and ____ of receptor. |
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Definition
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Term
| The secondary antibody response to a protein differs from the primary immune response in the amount of ___ formed, ___ period between Ag injection and height of humoral response, and the ____ of Ag induced response. |
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Definition
Ab; lag; specificity
one not chosen: susceptibility of immunosuppressive agents. |
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Term
| What type of reaction is tuberculin test? |
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Definition
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Term
| What type of reaction is asthma? |
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Definition
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Term
| What type of reaction is glomerulonephritis? |
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Definition
| Type III (immune complex) |
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Term
| What type of reaction is a reaction to an insect sting? |
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Definition
| Type I (anaphylaxis) reaction |
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Term
| What kind of reaction is a transfusion reaction? |
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Definition
| Type II (Cytotoxic) reaction |
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Term
| hat kind of reaction is serum sickness? |
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Definition
| Type III (Immune Complex) reaction |
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Term
| What kind of reaction required IgE? |
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Definition
| Type I (anaphylactic) reaction |
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Term
| What type of reaction is an arthus reaction? |
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Definition
| Type III (Immune complex) Reaction |
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Term
| What type of reaction is tumor cell surveillance? |
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Definition
| Type IV (cell-mediated) reaction |
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Term
| What is the largest immunoglobulin in molecular weight? |
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Definition
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Term
| What Ab class is capable of crossing the placenta? |
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Definition
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Term
| What Ab class is in the greatest concentration in plasma? |
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Definition
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Term
| What Ab class is first produced in response to antigen? |
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Definition
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Term
| What Ab class plays an important role in blood (ABO) transfusion reactions |
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Definition
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Term
| What Ab class is involved primarily in atopy allergic disease |
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Definition
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Term
| What Ab class possesses a secretory componen? |
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Definition
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Term
| What Ab class is present in plasma only in trace amounts (B cell bound) |
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Definition
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Term
| What Ab class provides mucosal immunity? |
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Definition
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Term
| What two antibody classes activate complement by the Classical pathway? |
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Definition
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Term
| The opsonin complement fragment that causes microorganism to better adhere to neutrophiles and macrophages? |
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Definition
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Term
| Complement component found in greatest concentration in plasma? |
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Definition
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Term
| Complement fragment most important for neutrophil chemotaxis |
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Definition
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Term
| Anaphylatoxins I and II are complement fragments |
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Definition
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Term
| Alternative pathway bypasses complement components ____ |
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Definition
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Term
| ___ competes with Factor B for binding to C3b and can also dissociate C3b,Bb |
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Definition
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Term
| complement components which are bacteriocidal to Gram-negative bacteria |
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Definition
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Term
| C1 is composed of __, __, and ___ parts head together by the metal ion ___. |
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Definition
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Term
| ____ enzyme converts Factor B to Bb in Alternative pathway |
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Definition
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Term
| The complement complex for C3 convertase via the Classical complement pathway is ________ |
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Definition
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Term
| The complement complex for C5 convertase via the Alternative complement pathway is ___ |
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Definition
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