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Immunology Exam 1
questions from old exams (2001, 2002, 2006) - don't contain repeated questions from 2009 & 2010 tests
46
Immunology
Professional
09/17/2011

Additional Immunology Flashcards

 


 

Cards

Term
Ubiquitin
Definition
imporant component in the processing of endogenously produced antigens
Term
Anergic
Definition
lymphocyte receives first signal without the costimulatory second signal
Term
CD3
Definition
associated with T cell receptor, responsible for signal transduction following antigen recognition
Term
MHC II
Definition
responsible for displaying foreign antigen that is produced within cell's cytoplasm
Term
CD8
Definition
associated with cytotoxic T lymphocytes ONLY
Term
Interferon
Definition
cytokine important in virus defense by creating an antiviral state
Term
High Endothelial Venule
Definition
cellular structure associated with lymphocyte extravasion in lymph nodes
Term
Fas Ligand
Definition
mediator of cytotoxicity by Tc lymphocytes
Term
Hypertension Due To Vasodilation
Definition
condition may occur upon massive release of inflammatory mediators
Term
Leukotriene
Definition
secondary mediater of mast cell
Term
Histamine
Definition
primary mediator of mast cell
Term
Integrin
Definition
cell adhesion molecule
Term
Tumor Necrosis Factor
Definition
cytokine
Term
Granzyme
Definition
mediator of cytotoxic T cell
Term
Immunoglobulin Light Chain
Definition
variable region has multiple V & J genes; constant region has a few C genes
Term
Immunoblogulin Heavy Chain
Definition
variable reagion has V, D & J genes; constant region has genes for each isotype (G, M, E, A, D)
Term
Naive Lymphocytes
Definition
haven't encountered antigen; randomly circulate through secondary lymph tissue; need 2 signals
Term
Memory Lymphocyte (or Effector)
Definition
have encountered an antigen; differentially recirculate; need 1 signal for activation
Term
Interleukin 10
Definition
cytokine; produced by B cells, T cells, monocytes/macrophages; down regulates expression of MHC II on macrophage surface; up regulates expression of Fc receptor on macrophage surface; stimulates B cells & NK cells
Term
B Cells
Definition
mature in bone marrow
Term
T cells
Definition
mature in Thymus
Term
Constant Region
Definition
mediates biological function
Term
Bone Marrow
Definition
site of rearrangement of Ig heavy & light genes in B cells
Term
MHC I
Definition
presents antigens to cytotoxic T cells
Term
MHC II
Definition
presents antigens to T helper cells
Term
MHC I
Definition
presents endogenous antigens
Term
MHC II
Definition
presents exogenous antigens
Term
Macrophage
Definition
"professional" antigen presenting cell
Term
CD3
Definition
cell surface molecule required for signal transduction on ALL T cells
Term
T Cell Receptor
Definition
mediates antigenic specificity of the T helper cell
Term
TH1
Definition
activates cell-mediated immunity
Term
TH2
Definition
activates humoral immunity
Term
Albumin
Definition
not a mediater of inflammation
Term
Cytotoxic T Cells
Definition
destroy target cells by inducing apoptosis
Term
Perioarteriolar Lymphoid Sheath
Definition
found in spleen
Term
Germinal Center
Definition
part of lymph node
Term
M Cell
Definition
found in intestines
Term
CD4
Definition
T helper cell
Term
CD8
Definition
cytotoxic T cell
Term
CD3
Definition
T cell
Term
Neutrophil
Definition
is a phagocyte
Term
Mast Cell
Definition
is a histamine
Term
Plasma Cells
Definition
secrete antibodies
Term
Interleukin
Definition
is a cytokine
Term
Protein
Definition
most effective immunogen
Term
MHC I
Definition
are not expressed on RBC, only nucleated cells
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