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Immunology and Serology
Discusses immunology and serology as it pertains to the lab
13
Medical
Undergraduate 2
04/25/2010

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Cards

Term

 

 

 

 

Immunology

 

 

 

Definition

 

 

defined as the study of the molecules, cells,

organs and systems responsible for the

recognition and disposal of nonself substances.

Term

 

 

 

Serology

 

Definition

 

 

a division of immunology that specializes in

laboratory detection and

measurement of specific antibodies

that develop in the blood during a

response to exposure to a disease

producing antigen.

Term

 

 

 

Immunohematology

Definition

- Blood Banking

- uses serologic methods to

determine blood groups and

unexpected antibodies in the blood of persons

donating or receiving blood.

Term

 

 

 

The function of the immune system

is ___________

 

Definition

 

 

to recognize "self" from "nonself" and to defend

the body against nonself substances

Term

 

 

The first line of defense

is ___________

Definition

 

-unbroken skin and mucosal membrane surfaces.

- "Physical barrier"

-Normal Flora found in certain parts of the body

(throat, intestines, ect..) facilitate the

elimination of foreign microorganisms from the body

-Other first lines: secretions (mucus, earwax,

lactic acid in sweat, stomach acid,

saliva and tears)

Term

 

 

Natural Immunity

Definition

 

one of the two ways body resists infection after the first line has been penetrated.

Term

 

 

Components of Nonspecific Natural Immunity

Definition

 

- phagocytic neutrophils and macrophages engulf invading foreign material.

-Complement proteins are the major fluid component

- Lysozymes and interferons are sometimes natural antibiotic.

*interferon is a family of proteins produced

rapidly by many cells in response of viral

infection and blocks replication of viruses in cells.

Term

 

 

Acquired or Adaptive Immunity

Definition

 

-allows the body to recognize, remember and respond to a specific stimulus (antigen).

Term

 

 

2 Types of Acquired immunity

Definition

 

 

1. Active- natural infection or artificial vaccination

2. Passive- natural transfer in vivo or clostrums

or artificial infusion of serum or plamsa.

Term

 

 

Cellular components of Acquired 

immunity 

Definition

 

Lymphocytes (T and B) selectively respond to nonself substances, which leads to immune memory and a permanent pattern of response.

Term

 

 

Humoral components of

Acquired immunity

Definition

 

antibodies and cytokines.

Term

 

 

Humoral Mediated Immunity

Definition

 

- acts as primary defense against bacterial infection.

- if the infection is natural the person builds antibodies

if the reaction is natural and passive a newborn recieves antibodies from the mother.

Term

 

 

Cell mediated immunity is responsible

for the body defense in what

immunologic events?

 

Definition

 

-contact sensitivity.

-immunity to viral and fungal antigen.

-immunity

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