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Immunology and Inflammation
module 2.1
11
Pharmacology
Graduate
11/22/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Bone Marrow
Definition
makes white blood cells, red blood cells, and platelets 
Term
granulocytes
Definition

Made by trilineage myeloid stemcells-

and produces...

neutrophils-main bacteria defence

eosinophils-parasitic defense

basophils/masts-allergic

Term
lymphocytes
Definition

come from bone marros to lymphoid stem cells and then

makes bcells

tcells

Term
megakaryocyte
Definition

from trilineage myleoid stems

precursor to platelets

Term
erythroblast
Definition

from trilineage myseloid stem

precursor to erthyrocytes

Term
Innate immune system
Definition

First response

for bacterial/parasitic infx

 

Innate system consists of:

granulocytes, mast cells, antigen presenting cells (macrophages, dendritic cells)

Term
Antigen Presenting Cells
Definition

role: phagocytosis of bacteria or parasite producing

antigens with MHC protein on surface

 

result: MHC class II causes cd4+t cells respond  for bacteria

 

-Nucleated cells /MCH I attract CD8+t cells for viruses (proteins displayed to differentiate from self)

 

-Adaptive immune system activated 

Term
ADAPTIVE Immune System
Definition

-specific response 

-generated MHC protein and displayed antigen causing B/T cell interaction

-Knows native/foreign

 

Term
Humoral Immunity
Definition
produce B cells (antibodies)
Term
Cellular Immunity
Definition

Produce...

 

Cytoxic T cells: CD8+ T cell that mediate cell death (Virus MHCI)

 

T-helper: CD4+ T cell that regulates cytokines-->B cell release(bacteria MHC II)

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