Term
IgG
How many classes?
Primary function?
Complement binding?
Opsonic?
Agglutination/precipitation? |
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Definition
How many classes? 4
Primary function? Predominant immunoglobulin in serum; passes from mom to baby through placenta
Complement binding? Yes
Opsonic? Yes
Agglutination/precipitation? Yes |
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Term
IgA
How many classes?
Primary function?
Complement binding?
Opsonic?
Agglutination/precipitation? |
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Definition
How many classes? 2
Primary function? Protection at mucosal surfaces, dimers held together by J chain, secretory chain wrapped around Fc regionns, makes IgA less susceptible to proteolytic cleavage
Complement binding? No- classical pathway, Yes-alternative pathway
Opsonic? Yes
Agglutination/precipitation? Yes |
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Term
IgM
How many classes?
Primary function?
Complement binding?
Opsonic?
Agglutination/precipitation? |
|
Definition
How many classes? No subclasses
Primary function? First antibody produced, low affinity, but multiple binding sites allow for higher avidity
Complement binding? Yes
Opsonic? Yes
Agglutination/precipitation? Yes |
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Term
IgD
How many classes?
Primary function?
Complement binding?
Opsonic?
Agglutination/precipitation? |
|
Definition
How many classes? No subclasses
Primary function? B cell maturation marker
Complement binding? No
Opsonic? No
Agglutination/precipitation? No |
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Term
IgD
How many classes?
Primary function?
Complement binding?
Opsonic?
Agglutination/precipitation? |
|
Definition
How many classes? No subclasses
Primary function? antiparasitic/ allergy
Complement binding? No
Opsonic? No
Agglutination/precipitation? No |
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