Term
| Difference between Ig and Ab |
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Definition
| Ab is an Ig that is made in response to and binds to a particular antigen |
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Term
| Ig in descending order of concentration |
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Definition
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Term
| Two fragments that Ig will split into if digested by papain |
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Definition
Fab - fragment, antigen binding
Fc - important in complement activation |
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Term
| difference between isotype and idiotype |
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Definition
isotype = IgG and IgA
idiotype = one IgG molec and another IgG molec (perhaps from a different B cell) |
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Term
Name that Ig!
Found in serum, great at neutralization
opsonization
complement activation
crosses placenta |
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Definition
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Term
Name that Ig:
pentamer, first formed in initial immune response, great at neutralization, complement activation, does not cross placenta |
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Definition
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Term
Name that Ig:
dimer, has a secratory component, neutralization, present in breast milk |
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Definition
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Term
Name that Ig:
Low in serum, mediates allergic reactions, defends against parasitic infections |
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Definition
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Term
Name that Ig:
low levels in plasma, found on b cell surface, antigen receptor |
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Definition
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Term
| What Ig are present on the surface of a mature B cell before isotype switching |
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Definition
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Term
| Characteristics of T dependent antigens |
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Definition
| require antigen processing, require the assistance of CD4 Tcells (type 2) |
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Term
| Th1 induces which isotype switching in which Ig? |
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Definition
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Term
| Which cytokine induces growth and isotype switching to IgG1 and IgE |
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Definition
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Term
| Which cytokine enhances differentation of B cells into plasma cells? |
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Definition
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Term
| Which cytokine shares functions with IL 4 |
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Definition
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Term
| What Ig is the first to respond in a primary T dependent Ab response? |
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Definition
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Term
| characteristics of secondary Ab response |
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Definition
| more rapid, more intense, more prolonged, IgM is not first Ab produced, affinity maturation |
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Term
| characteristics of t independent antigens |
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Definition
usually carbohydrates, dont need to be processed, bind directly to Ig receptors
no memory cells formed, only IgM is produced
children under 2 have poor response |
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