Term
| Normal functions of the immune system |
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Definition
| protect from infectious disease, prevent access of microorganisms, inhibit microorgo growth, neutralize toxins, ect. |
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Term
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Definition
| Cells are specific to a target. For example, immune cells that attack the flu virus dont attack bacteria that cause strep |
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Term
| Name 2 abnormal/aberrant functions of the immune system |
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Definition
autoimmunity
immune pathology - when immune response causes collaterl damage to the host tissue |
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Term
define primary lymphoid tissue
give two examples |
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Definition
tissues that give rise to leukocytes
Bone marrow - major site of hematopoiesis
thymus - produce T cells |
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Term
What happens in secondary lymphoid tissues?
Give example of such tissues |
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Definition
Places where lymphocytes can interact with antigens
Spleen - responsive to blood borne pathogens
lymph nodes - responsive to antigens in the skin, mucous membranes, or internal organs
MALT (mucosal associated lymphoid tissue) - nonencapsulated, found in submucosal areas |
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Term
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Definition
| protein molecules that bind to specific receptors and cause changes in the activation state of a cell or induce certain actions |
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Term
Function of:
basophil
mast cell
eosinophils |
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Definition
mediates allergic response, inflam
mediates allergy and inflam
phago and inflam |
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Term
Function of:
neutrophils
macrophages
NK cells |
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Definition
phago and inflam - most important in adaptive immunity
antigen presentation
killing infected cells
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Term
| Characteristics of innate immunity |
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Definition
| first line of defense, do not change or adapt, can include mechanical, chemical, and structural factors in addition to lymphocytes |
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Term
| Name endogenous pyrogens produced by macrophages |
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Definition
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Term
| characteristics of adaptive response |
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Definition
| can distinguish between self and non self, take longer to respond (7-10 days), have memory, self-regulating |
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Term
| Example of passive and active immunity |
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Definition
passive - mother passes immunity to child during breat feeding
active - person gets a disease and overcomes it |
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Term
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Definition
| substance that can inducue a specific immune response |
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Term
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Definition
| molec that binds with products of immune response but may or may not induce an immune response |
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Term
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Definition
| substance administered with an immunogen that enhances the immune response |
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Term
How do these properties affect immunogenicity:
charge
shape
size
complexity |
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Definition
charge - none
shape - none
size - bigger = more immunogenic
complexity - more complex = more immunogenic |
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Term
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Definition
| subtance which non specifically activates lymphocytes to undergo cell division |
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