Term
| What is drug of choice for Stenotrophomonas |
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Definition
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Term
| Drug of choice for Candida Albicans? |
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Definition
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Term
| What are the antistaphylococcal PCNs? |
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Definition
Methicillin, nafcillin, oxacillin, dicloxacillin
Drug of choice for MSSA |
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Term
| What are the aminopenicillins |
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Definition
Ampicillin and amoxicillin
Better gram - than PCN |
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Term
| Cephalosporins do not cover what? |
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Definition
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Term
| What is the drug of choice for enterococcus |
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Definition
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Term
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Definition
Ancef
1st generation cephalosporin
Primarily gram + coverage |
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Term
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Definition
Keflex
1st generation cephalosporin
Oral |
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Term
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Definition
Mefoxin
Cephamycin (2nd generation cephalosporin)
More gram - than 1st generation
Good anaerobic coverage |
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Term
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Definition
Zinacef, Ceftin
2nd generation cephalosporin |
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Term
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Definition
Ceclor
2nd generation cephalosporin
Lots of rash |
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Term
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Definition
Omnicef
2nd generation cephalosporin
Good for kids bc it tastes good |
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Term
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Definition
Claforan
3rd generation cephalosporin
More gram - than 2nd generation |
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Term
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Definition
Rocephin
3rd generation cephalosporin
Biliary sludging, will precipitate with Ca containing foods |
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Term
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Definition
| 3rd generation cephalosporin |
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Term
|
Definition
Vantin
3rd generation cephalosporin
Oral - step down therapy for Ceftriaxone |
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Term
|
Definition
Suprax
3rd generation cephalosporin
good for gonorrhea |
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Term
|
Definition
Ceftaz
3rd generation cephalosporin
has pseudomonal coverage and lacks good step coverage |
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Term
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Definition
Maxipime
Good gram + and - including pseudomonas
SE: seizures |
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Term
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Definition
Primaxin
Carbapenem
cilastatin is a renal dihydropeptidase inhibitor |
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Term
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Definition
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Term
|
Definition
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Term
|
Definition
Invanz
carbapenem
no pseudomonas coverage and is dosed once daily |
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Term
| carbepenem coverage and SE |
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Definition
broad coverage - dose not cover MRSA or stenotrophomonas
SE: seizures (most with imipenem)
Use meropenem with meningitis patients |
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Term
|
Definition
Azactam
monobactam
used in patients with PCN allergy |
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Term
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Definition
Cubicin
Do NOT use for pneumonia
used for MRSA skin infections, bacteremia, and endocarditis
Monitor CPK weekly due to risk of myalgias, IV only |
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Term
| quinupristin/dalfopristin |
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Definition
Synercid
gram + activity only including VRE
E. faecium NOT faecalis |
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Term
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Definition
Zyvox
used for skin infections and pneumonia, not bacteremia
SE: thrombocytopenia risk increases greatly after 2 weeks
It is weak MAOI so care for serotonin sydrome with SSRIs, tyramine containing foods, etc. |
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Term
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Definition
Teflaro
Only MRSE cephalosporin
Little gram - activity and no enterococcus activity like all other cepholosporins |
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Term
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Definition
Biaxin
macrolide
keep suspension and room temp |
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Term
tetracyclines
Examples
Uses
SE |
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Definition
Ex. tetracycline, doxycycline, moinocycline
primarily used for MRSA skim infections, not great vs strep
Avoid in pregnancy and kids under 8 due to discolor teeth |
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Term
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Definition
| Vanc, linezolid, tigecycline, daptomycin, ceftaroline |
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Term
| What drugs treat pseudomonas |
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Definition
| Zosyn, aztreonam, aminoglycoside, cipro, levaquin, ceftazidime, cefepime, carbapenems (not ertapenem) |
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Term
| What drugs can increase QTc |
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Definition
| fluoroquinolones, macrolides, telavancin |
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Term
| what drugs increase photosensitivity |
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Definition
| fluoroquinolone, tetracycline, bactrim, tigecycline, voriconazole |
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Term
| what drugs have disulfiram reaction |
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Definition
| cefotetan, metronidazole, tinadizole |
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