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ID Final
STD
78
Architecture
8th Grade
12/06/2012

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Term
is sexual contact theonly mode of transmission for STDS?
Definition
NO!!!!!
Term
a person with 1 STD will probbaly also have?
Definition
another STD
Term
STDS are gnerally spread by what ppl?
(2)
Definition
asymptomatic
have symptoms but ignroing them
Term
what is a common misconception by ehalth care providers?
Definition
patient NOT at risk for STD
Term
how can STD be prevented-
(2)
Definition
-abstinence
-monogomous with uninfected aprtner
Term
2/3 of cases are what age?
which gender is more %?
which are higher % races?
Definition
teens-20s
male
african> am indian> hispanic
Term
Risk factors for STDs-6
Definition
sex active
multiple sex ppl in 6 months
previous STD
prostitues
homo sex (MSM)
sex w/ drugs
Term
prevention methods for STDs -3
Definition
edicate high risk ppl
eval, educate sexual partnerrs
pre-exposure vaccines
Term
time and sensitivity of STD diagnositc tests?
cost of tests?
Definition
take time, suboptimal sens.
higher cost than empiric therapy
Term
ideal therapy of STDs
Definition
single dose, affordable
Term
what are the congenital infections?
-4
which isn't transmitted thru birthing?
Definition
chalmydia, gonorrhea, HSV, syphillis
-syphillis
Term
which 3 infections are urethritis/cervicitis
Definition
gonorrhea
chlamydia
trichomoniasis
Term
which 3 infections are genital lesions
Definition
syphillis
genital herpes
genital warts
Term
which 3 infections are vaginosis
Definition
bacterial vaginitis
trichomoniasis
vulvovaginal candidiasis
Term
which is the 2nd most reported STD in US?
Definition
gonorrhea
Term
for gonorrhea which transmission is higher? (M-> F, F->M)
Definition
male to female
Term
pathphys of gonorrhea -3
Definition
1)G attaches to epitheial cell w/ pili
2) G is pinocytosed into cell
3)PMNs invade tissue-> purulent exudates
Term
neisseria gonorrhea is a gram?
Definition
negative diplococcus
Term
diagnosis of gonorrhea may be made by-4
which is the only one to provide resistnace data?
Definition
culture, NAATS, enzyme immunoassay, gram stain;
culture
Term
clinical presentation of gonorrhea of males
what are the complications?
Definition
urethritis, dysuria, white urethral discharge;
they are rare- proctitis
Term
what % of females are asymtpomatic for gonorrhea?
Definition
80
Term
what are the symptoms of females with gonorrhea
complications?
Definition
dysuria, vaginal discharge, uterine bleeding;
pelvic inflamm disease, infertility
Term
what disease in seen in untreated gonorrhea patients? what are the symptoms?
Definition
disseminated gonoccocal infection
systemic symptoms, skin lesions, arthrites
Term
gonorrhea med resisitance:
which meds are due to plasmid resistance? (4)
Definition
penicillins, tetracyclines, spectinomycin, FQs
Term
gonorrhea med resisitance:
which med class has a rapid resistance and so no longer reccomended
Definition
FQs
Term
gonorrhea med resisitance:
which med is no longer reccomedned to recent increaeses in resitance?
Definition
cefixime
Term
for gonorrhea treat partners within past _ days?
how long do they need to not have sex?
Definition
60
7 days after single dose of med
Term
with gonorrhea what co infection do you always treat for?
which gneder has this coninfection more?
Definition
chlamydia
females
Term
what is the most most common reported STD in US?
which gender has it more?
Definition
Chlamydia
woomen
Term
what type of organsim if clhmaydia
Definition
obligate intracellular
Term
chlamydia uses what for replication?
what does it retain thruought devlopement tho?
Definition
host material
cellular identity
Term
how is chlamydia diagnosed
Definition
nonculture technique NAAT
Term
inflammation from chlamydia can lead to 2 things?
Definition
scarring and infertility
Term
annual screening for chalmydia is reccomedned for who? -3
Definition
sex active women <20-25 yrs
preggo
older women w/ risk factors
Term
-% of males are asymp for Chlamydia
what are syomtpoms? 3
what are complications? 3
Definition
50
urethritis, dysuria, genital itching
rare-prostatitis, proctitis, reiter's
Term
-% of women are asmpyt for chlamyd?
what are symptoms? 3
complications? 3
Definition
75
itching, vaginal discharge, pain with urination/intercourse;
PID, infertitlity, ocular trachoma
Term
syphillis reach _ in 2000
Definition
nadir
Term
syphillis has _% for aquisition rate with SINGLE exposure
Definition
50-60
Term
untreated syphillis has _ % perinatal mortality
Definition
40
Term
what is the infectious agent of syphillis?
what kind of org is it?
Definition
treponema pallidum
spirochete
Term
what diagnostic tests are used for syphillis
Definition
smears or serologic (RPR, VDRL)
Term
what is the name of the presentation in stage 1 of syphillis
Definition
chancre- 1 oe more nontender papulaes in genitals
Term
is chancre contagious?
how long deos it take to resolve?
Definition
yes, very
spontaneoulsy in 3-6 wks
Term
which stage of syphillis is called latent?
Definition
3
Term
2nd syph stage has what presentation- (2)
Definition
mucocutaneous eruptions, nonpruirutic rash on trunk, oral, genitals, palms/soles
Term
is the 2nd stage of syph contagious?
Definition
only the mucosal legions
Term
how long does it take for 2nd stage syph to appear
Definition
if not treated 2 wks after chancre
Term
which syph stage is asymptomatic?
Definition
3rd
Term
early latent(syph( defined as?
is late latent infectious?
Definition
1 yr from onset (contagious)
no, but still host
Term
symtpoms of syph stage 4- (2)
Definition
inflamm of organ system
Gummas- benign grnalumatous lesion on bone, skin, URT, heart
Term
stage 4 syph occurs in _% untreated
occurs _ yrs after onset
Definition
25-30
2-3
Term
neurosyphillis occurs at what stage?
symtpoms- 4
Definition
any
hemiplegia, seizures, pain in back/legs, blader disturbed
Term
patients with just syphillis need serologic follow up _ months after theray?
what if HIV patient?
Definition
6 & 12;
every 3
Term
whcih infection has jarisch-herxheimer rxn?
what is it?
when does it occur?
Definition
syphillis
febrile rxn- fever, chills, tachycardia
24 hrs after intital treatment
Term
genital herpes last how long?
Definition
lifelong
Term
genital herpes is what type of org?
Definition
doube stranded DNA vrius
Term
what are the two serotypes of genital herpes?
which causes recurrence? which causes 30% of 1st episodes?
Definition
HSV-1, HSV-2;
HSV-2
HSV-1
Term
diagnosis of genital herrpes is done 2 ways
Definition
PCR or cell culture
Term
presentaiton of primary genital herpes-3?
which gender has more severe symptoms, and whats a common one?
Definition
fever, headache, fatigue
women-cervicitis
Term
genital lesions appear _ days after contact of GSV?
painful ulceration last?
viral shedding lasts?
Definition
2-7
7-14 days
11-12 days
Term
secondary genital herpes:
_ % in first year
are vesicle few/more heal faster/slower?
viral shedding lasts?
Definition
80
fewer, fasterr(3-10 days)
4 days
Term
if preggo has active genital herpes, what should be done during birth?
Definition
c-section
Term
effective therapy for genital herpes requires therapy within-
Definition
1 day of lesion onset
Term
what is prodrome and when is it present?
Definition
burning,tingling 18-36 hrs before lesion;
secodnary genital herrpes
Term
HPV is associated with increased _ cancer
Definition
cervical
Term
what type of organism is HPV
Definition
nonenveloped, DS DNA virus
Term
which STD cannot be cultured
Definition
HPV
Term
presentation of HPV-2
Definition
anogenital warts, condylomota
Term
is HPV usually asypmtomatic?
Definition
yes
Term
treatment for HPV-3
Definition
removal of lesion by cryotherapy, topical acids, surgery
Term
HPV vaccine is reccomended for?
Definition
females/males 9-26 yrs
Term
what HPV strains are most cancerous?
which cause genital warts
Definition
16,18
6,11
Term
HPV admin
Definition
3 Sq IM in 6 mos
Term
what are the two HPV vaccines, and what strains do they coverr
Definition
Gardisil- 6,11,16,18
Cervarix- 16,18
Term
vaginosis cover infections with-
whihc is the only strict STD
Definition
vaginal discharge
trichomonaisis
Term
what species causes bacterial vaginosis
Definition
gardnerella vaginalis
anaerobe bacteria
Term
what type of org causes trichomoniasis
Definition
anaeorobe, flagela, protozoan
Term
what species (and type of org) causes vulvovaginal candidasis
Definition
candida albicans
budding yeast
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