Term
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Definition
| disease that goes over population in confined area |
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Term
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Definition
| disease that accumlates to pop over continent |
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Term
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Definition
drift: small changes in the virus over time. new virus strains not recognized
shift: abrupt major change, 2 strains make new subtype. |
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Term
| herpes zoster is a reactivaiton of _ |
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Definition
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Term
| _/3 ppl will get shingles |
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Definition
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Term
| more cases of herpes zoster in ages > |
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Definition
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Term
| risk factros for shingles |
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Definition
older age
immunocompro
local trauma of spine
splenecotmy
family history of shingles |
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Term
| after initial infection where does herpes zoster stay dormant in? |
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Definition
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Term
| reactivaiton of herpes zoster occurs when _ immunity loweers |
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Definition
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Term
| what 2 peripheral sensory nerves does herpes zoster travel on |
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Definition
trigeminal
thoracic ganglia |
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Term
| how long can the prodrome of herpes zoster last? |
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Definition
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Term
| symtpoms of herepes zoster prodrome- 6 |
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Definition
burning, los of sensation, or knife like pain
headache, photophobia, fever |
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Term
with acute shingles pain occurs along?
-most common sites? |
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Definition
dermatomes
chest, abs, neck, eye |
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Term
| in acute shingles the rash is _ |
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Definition
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Term
| postherpetic nueralgia defined as |
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Definition
| pain 12 days after onset of rash or after cutaneous healing |
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Term
| psot herpetic neuralgia pain descr as |
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Definition
| stabbing, burning, electric |
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Term
| incidence and duration of post herpetic nueralgia directly related to |
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Definition
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Term
| when do you treat patients for shingles? 2 |
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Definition
| mod/severe pain or age >50 |
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Term
| what type of med does NOT help post herpetic nueralgia |
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Definition
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Term
| 2 types of shingles prevention |
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Definition
variciella vaccine
herpes zoster vaccine |
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Term
varicella vaccine prophylaxis:
dead/ alive?
attenuated/non attenuated?
how mnay doses? at what times?
how effective? |
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Definition
live, attenuated
2 doses- first 12-15 months, then 4-6 years
70% |
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Term
Zostovax:
dead/alive; attenuated?
same strain but _ x higher
effectivenes? |
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Definition
live attenuatedd
14
61% reduction for effective |
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Term
do not give zostovax to?
who is it reccomednded for? |
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Definition
children
immune competent, age >60 |
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Term
| how long does zostovax last? |
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Definition
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Term
| cytomegalovirus is a _ virus |
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Definition
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Term
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Definition
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Term
| CMV lasts how long? what kind of symptoms? |
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Definition
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Term
| populations at risk for CMV |
|
Definition
newborns
HIV- retinits
stem cell/organ transplant |
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Term
| congenital CMV is one of the leadings causes of _ |
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Definition
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Term
| CMV in newborns can result in- 3 |
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Definition
| hearing loss, vision loss, retardation |
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Term
| bc fo CMV risk- _ needs to be idenitfiied of donor and receipeint of trnasplant |
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Definition
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Term
| CMV can also affect _ survivial in transplant |
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Definition
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Term
| immunization available for CMV prevention? |
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Definition
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Term
| Meds available for CMV prevention-2 |
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Definition
valganciclovir
ganciclovir |
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Term
| what virus is the 7th leading cause of deaht in US? |
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Definition
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Term
| flu peaks during what months? |
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Definition
|
|
Term
what 2 classes of the flu are most common?
which develops in childhood?
which is more severe |
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Definition
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|
Term
whcih type of flu also has surface glycoproteins?
what are they? |
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Definition
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Term
| which glycoprotein is involved in host cell binding prior to flu virus entry |
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Definition
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Term
| which glycoprotein is needed for flu virus rlease and propogation |
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Definition
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Term
flu virus is carried from _?
_ tansmission can also occur |
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Definition
respiratory droplets
contact |
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Term
|
Definition
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Term
| how long is incubation for flu virus |
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Definition
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Term
| ppl at higher risk for flu complications-6 |
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Definition
< 2 yrs
65+
preggo
AM. Indian
BMI>40
AGE<19 w/ aspirin |
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Term
| signs of the flu in 50% of patients |
|
Definition
| fever, sore throat, cough |
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Term
| influenza can also present as _ |
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Definition
|
|
Term
what are the complications of influenza
-4 |
|
Definition
exacerbation of med condtion
bacteria superinfection
cardiac, seizure, muscles
thrombosis |
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Term
what is the Lab testing for influenza
-% os sensitivity?
% of specificity? |
|
Definition
rapid point of service
60-80
90 |
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Term
| to confirm 2009 H1N1 need what test? |
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Definition
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|
Term
| when is rapid testins of flu not essential |
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Definition
| if virus prevalent in community |
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Term
| what is current recocmendation for flu vaccine? |
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Definition
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Term
| flu vaccine reccomended for ages? |
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Definition
|
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Term
| what are the 2 types of flu vaccines |
|
Definition
trivalent inactivated;
live attenuated |
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Term
for the TIV:
how is it admin?
side effect? |
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Definition
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|
Term
FLu Zone high dose is what type of vaccine?
what age group is it for?
what is a con? |
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Definition
trivalent inactivted
65+
more side effects |
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Term
brand name of the LAIV?
admin?
what pop is it given to?
side effects? (2) |
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Definition
Flu Mist
nasal spray
healthy 2-49 yrs
sore throat, nasal stuffiness |
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Term
| what is the new reccomednation about eggs allergy and the flu |
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Definition
| if had hives or rash- get TIV and monitor for 30 min |
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Term
| what drug class cannot be used to PREVENT symtpoms like pain and fever flu vaccine |
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Definition
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Term
| when is pharmacologic prophylaxis reccomended for influenza- 3 |
|
Definition
-high risk that cant get vaccine
-household w/ infected ppl
-long term care facility |
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Term
| when should you not get prophylaxis for influenza |
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Definition
| while developing response to LAIV (2 wks after admin) |
|
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Term
| what are the reccomended pharm prophylaxis for influenza |
|
Definition
TAMIflu-oselTAMIvir
relenZa-Zanamivir |
|
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Term
| which pharm agents are not recocmended for flu prophylaxis |
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Definition
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Term
How many hours of flu symtpom onset do you want to start treatment?
do you wait for lab result? |
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Definition
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|
Term
when may treatment be beneficial for flu even after the reccomended hrs
-2 |
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Definition
|
|
Term
| what are the beenfits from treatment for flu |
|
Definition
decreased duration
nasal shedding of virus
decrease severity |
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Term
patients who should get flu therapy?
(3) |
|
Definition
hospitalized
severe, complicated illness
the list of ppl at higher risk of complication |
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Term
almost all flu type _ is resistant to older agents
ALL of type _ is resistant |
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Definition
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