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Hypothalamus
Test 4 Material
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Graduate
03/30/2011

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Term
Name 3 regions of the hypothalamus
Definition
Supraoptic
Tuberal
Mammillary
Term
Part of hte diencephalon that is closely related to the pituitary gland.
Definition
Hypothalamus
Term
Regulates autonomic reactions: HR, BP, water metabolism, general metabolism, sexual behavior, temperature, GI activity, etc.
Definition
Hypothalamus
Term
The hypothalamus helps with elaboration of emotional responses. Name 4.
Definition
Aggression
Anger
Rage
Placidity
Term
Modulates both sympathetic and parasympathetic responses
Definition
Hypothalamus
Term
Anterior and medial hypothalamus
Definition
Parasympathetic
Term
Posterior and lateral hypothalamus
Definition
Sympathetic
Term
What is the anterior boundary of the hypothalamus?
Definition
Lamina Terminalis
Term
What is the superior boundary of the hypothalamus?
Definition
Hypothalamic Sulcus
Term
What is the inferior boundary of the hypothalamus?
Definition
Optic chiasm and tracts; posterior edge of mammillary bodies
Term
What is the posterior boundary of the hypothalamus
Definition
Mammillary bodies
Term
The inferior border of the hypothalamus, between the optic chiasm and the mammillary bodies is referred to as what?
Definition
Tuber Cinereum
Term
Which region of the hypothalamus is just above the optic chiasm?
Definition
Anterior region (supraoptic)
Term
Which region of the hypothalamus is just above the tuber cinereum?
Definition
Tuberal Region
Term
Which region of the hypothalamus is just above and includes the mammillary bodies?
Definition
Posterior region (mammillary)
Term
Each region of the hypothalamus is subdivided into medial and lateral areas by what?
Definition
Fornix
Term
What runs through the hypothalamus and subdivides the regions into medial and lateral areas?
Definition
Fornix
Term
Each area of the hypothalamus contains many ___ which subserve a variety of functions.
Definition
Nuclei
Term
Name 2 places that afferent input to the hypothalamus comes from.
Definition
Forebrain
Brain Stem / Spinal Cord
Term
Includes afferents from the limbic system, retina, and other areas
Definition
Afferents from forebrain
Term
Information comes from the hippocampus to the hypothalamus via what?
Definition
Fornix
Term
Information comes from the amygdala to the hypothalamus via what?
Definition
Stria terminalis
Term
The amygdala and the hippocampus come from what system?
Definition
limbic
Term
Sensory input from a variety of areas/nuclei - much reaches the hypothalamus via the Dorsal Longitudinal fasciculus
Definition
Afferents from Brain Stem / Spinal Cord
Term
The hypothalamus sends information to the brain stem to control the ANS via what?
Definition
Dorsal Longitudinal Fasciculus
Term
Lesions of the hypothalamic efferents (DLF) to the brain stem/spinal cord yield what?
Definition
Horner's Syndrome
Term
Information coming from the limbic system/ spinal cord is also going back to the limbic system/ spinal cord.
Definition
Reciprocal connections
Term
Sends efferents to the same area from which received afferents.
Definition
Reciprocal Connections
Term
There is 1 exception to hypothalamic efferents. What is it?
Definition
Hypothalamus sends information to the thalamus - mammillary bodies to thalamus via mammillothalamic nuclei
Term
Efferent information can go from the hypothalamus to the thalamus via what?
Definition
Mammillothalamic tract
Term
The most functionally important efferent connections of the hypothalamus are with what?
Definition
Pituitary Gland
Term
What is another term for the pituitary gland?
Definition
Hypophysis
Term
Name 2 things the Pituitary Gland is composed of.
Definition
Posterior Portion - Neurohypophysis
Anterior Portion - Adenohypophysis
Term
What is the name for the posterior portion of the pituitary gland?
Definition
Neurohypophysis
Term
What is the name for the anterior portion of the pituitary gland?
Definition
Adenohypophysis
Term
How is the hypothalamus connected to the neurohypophysis?
Definition
Neural Pathways
Term
How is the hypothalamus connected to the adenohypophysis?
Definition
Hypophyseal portal vessels
Term
Contains many well-delineated nuclei which make connections with, and provide control over, the hypophysis
Definition
Hypothalamus
Term
Name the nuclei that connect with the posterior pituitary (neurohypophysis)
Definition
Supraoptic (SON)
Paraventricular (PVN)
Term
What 2 nuclei contain large neurons and send their axons into the neurohypophysis, releasing their products into the vasculature of the neurohypophysis, and thus into the general circulation?
Definition
SON
PVN
Term
Releases corticotropin-releasing hormone as well as oxytocin, and vasopressin.
Definition
PVN
Term
Causes the release of ACTH (adrenocorticotropic hormone) by anterior hypophysis.
Definition
Corticotropin-releasing hormone
Term
Stimulates the adrenal gland to produce steroids
Definition
ACTH
Term
What 2 hormones do BOTH SON and PVN release?
Definition
Oxytocin
Vasopressin
Term
Causes uterine contraction during labor and initiates milk secretion from mammary glands.
Definition
Oxytocin
Term
What is another term for vasopressin?
Definition
ADH (Antidiuretic Hormone)
Term
Alters membrane permeability of collecting ducts and convoluted tubules of kidney so that their membranes become more permeable to water. Causes decreased urine volume, increased body water, and increased BP.
Definition
Vasopressin
Term
Secretes hormones into the hypophyseal portal vessels in the median eminence.
Definition
Hypothalamus
Term
Hormones made by the anterior pituitary are carried by __ to secretory cells of the adenohypophysis which then release, or stop releasing, hormones in response to the factors released by the hypothalamus.
Definition
Portal veins
Term
Name the nuclei that connect to the adenohypophysis.
Definition
Arcuate
Periventricular
Suprachiasmatic
Ventromedial
Lateral
Term
What hormones does the arcuate nucleus release?
Definition
Growth Hormone - Releasing Hormone
Gonadotropin-Releasing Hormone
Term
Causes the release of the growth hormone from the anterior pituitary.
Definition
Growth Hormone - Releasing Hormone
Term
Stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary.
Definition
Gonadotropin-Releasing hormone
Term
Promotes growth of the ovarian follicles
Definition
FSH
Term
Induces ovulation; in males, it stimulates the production of testosterone.
Definition
LH
Term
What hormones does the periventricular nucleus release?
Definition
Thyrotropin-Releasing Hormone
Somatostatin
Term
Stimulates the release of thyroid stimulating hormone (TSH) by the anterior pituitary.
Definition
Thyrotropin-Releasing Hormone
Term
Inhibits the release of growth hormone by the anterior pituitary.
Definition
Somatostatin
Term
Has direct connections with the retina; controls circadian rhythms (sleep/wake cycles)
Definition
Suprachiasmatic Nucleus
Term
Involved with the regulation of food intake. Lesions of these will produce the opposite effect.
Definition
Ventromedial and Lateral Nuclei
Term
Decreases appetite.
Definition
Stimulation of VMN
Term
Increases appetite.
Definition
Stimulation of Lateral Nucleus
Term
What occurs with a VMN lesion?
Definition
Increased appetite
Term
What occurs with a lateral nucleus lesion?
Definition
Decreased appetite
Term
Maintenance of set-point for body temperature.
Definition
Posterior hypothalamus
Term
Name 2 symptoms of diabetes insipidus
Definition
polydipsia
polyuria
Term
Due to decreased or absent production of vasopression. Or lesions to the supraoptic/paraventricular nuclei.
Definition
Diabetes Insipidus
Term
What 2 things is the optic chiasm close to?
Definition
Thalamus
Pituitary gland
Term
A tumor that can cause loss of visual field, appetite changes, and likely to have diabetes insipidus.
Definition
Craniopharyngoma
Term
Releases products directly into the general circulation through the vasculature of the posterior pituitary
Definition
Neurohypophysis
Term
Secretes hormones into the hyopophyseal portal vessels in the median eminence.
Definition
Adenohypophysis
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